Clinical trials: Low-Birth-Weight
Iron Deficiency Anemia
Donor Breast Milk 2
The goal of this clinical trial is to determine the serum ferritin level and hematocrit level in very preterm infants receiving donor breast milk(DBM) with an early iron supplementation protocol .
- Trial name
- NCT07816601
- Testing
- Ferrous Sulfate Oral Product
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- AdventHealth
Infant, Newborn, Infant, Small for Gestational Age
Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants
The Milk Trial seeks to determine the effect on neurodevelopmental outcomes at age 22-26 months of donor human milk as compared to preterm infant formula as the in-hospital diet for infants whose mothers choose not to provide…
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Extremely Low Birth Weight
- Trial name
- NCT01534481
- Testing
- Donor Milk, Preterm Formula
- Where
- 17 sites in United States
- Volunteers
- 483 people
- Sponsor
- NICHD Neonatal Research Network
Very Preterm Maturity of Infant, The Risk Factors for Improving the Prognosis of VLBW Infants
Analyses of Anemia in Very Low Birth Weight (VLBW) Infants.
To study and analyze the association of the severity of anemia with neonatal morbidity and the risk factors of anemia in ealry life (less than 3 days of life) among the very low birth weight (VLBW) infants.
- Trial name
- NCT05949788
- Testing
- No intervention
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Shenzhen Bao'an Maternal and Child Health Hospital
Birth Asphyxia, Very Low Birth Weight Baby
Naushero Feroze Neonatal Survival Project
The present study will be carried out in close collaboration with the National Program for Lady Health Workers, a Ministry of Health program with 100,000 Lady Health Workers covering 60% of the rural population of Pakistan.
- Conditions
- Birth Asphyxia, Very Low Birth Weight Baby, Neonatal Sepsis
- Trial name
- AKU (NCT01350765)
- Testing
- Intervention, Control
- Where
- Pakistan
- Volunteers
- 37,201 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Prematurity, Respiratory Distress Syndrome
Autologous Umbilical Cord Blood Transfusion for Preterm Neonates
This is a pilot study to test feasibility of collection, preparation and infusion of a baby's own (autologous) umbilical cord blood in the first 14 days after birth if the baby is born premature <35 weeks of gestation.
- Conditions
- Prematurity, Respiratory Distress Syndrome, Anemia of Prematurity, Intraventricular Hemorrhage
- Trial name
- NCT01121328
- Testing
- Autologous cord blood transfusion for preterm neonates, Autologous cord blood transfusion
- Where
- Egypt
- Sponsor
- Sahar M.A. Hassanein, MD
Infertility, Obesity
Weight Management Intervention for Obese Women and the Live Birth Outcome of in Vitro Fertilization (IVF)
The primary aim of the study is to evaluate if weight management intervention for obese women (BMI≥30<35 kg/m2) prior to IVF improves the outcome assessed as live birth per participating woman, as compared to women where no…
- Trial name
- NCT01566929
- Testing
- Low calorie diet treatment
- Where
- 9 sites in Denmark, Iceland and 1 more
- Volunteers
- 317 people
- Sponsor
- Sahlgrenska University Hospital
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Thromboembolism, Postpartum DVT
Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery
The aim of this study is to evaluate the efficacy of two dosing regimens of low molecular weight heparin (LMWH) to reach prophylactic anti-factor Xa levels in post-cesarean delivery women.
- Conditions
- Thromboembolism, Postpartum DVT, Thrombosis
- Trial name
- NCT04305756
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Utah
Low Birth Weight Babies, Kangaroo Mother Care Scale up
Implementation Research on Scaling up Kangaroo Mother Care (KMC)
This implementation research aims to accelerate effective and high coverage of Kangaroo Mother Care in district Sonipat in the state of Haryana, India. The project is being led by government of Haryana.
- Trial name
- KMC-Scaleup (NCT03098069)
- Where
- India
- Volunteers
- 911 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Birth Weight
Effect of Energy Dense Biscuits in Undernourished Women on Birth Weight of Their Neonates
A nutrition trial which is based on the evidence that multivitamins \& micro nutrients provided during pregnancy in malnourished women will improve neonatal birth weight. There will be two arms.
- Trial name
- NCT02294240
- Testing
- Energy dense biscuits, Wheat Flour, oil, iron & Folic acid
- Where
- 2 sites in Pakistan
- Volunteers
- 224 people
- Sponsor
- Aga Khan University
Neonatal Sepsis, Low Birth Weight
Safety of Skin Cleansing With Chlorhexidine in Preterm Low Birth Weight Infants
The purpose of this study is to examine if single skin cleansing with 0.25% chlorhexidine affects skin condition, temperature, and bacterial colonization in stable preterm (28-36 weeks gestational age) low birth weight (1001-2000…
- Trial name
- NCT00947518
- Testing
- Chlorhexidine, Normal saline
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Very Low Birth Weight Infant
Olfactory Stimulation for Very Low Birth Weight Infants
This is a RCT study examining whether odor administration to mothers of very low birth weight infants promotes stabilization of vital signs compared with common nursing care.
- Trial name
- NCT05406804
- Testing
- Olfactory stimulation, Routine nursing care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Apnea of Prematurity
Caffeine for Apnea of Prematurity-Sleep (CAP-S) Study
Apnea of prematurity is a common condition that is usually treated with methylxanthines. Methylxanthines are adenosine receptor blockers that have powerful influences on the central nervous system.
- Trial name
- CAP-S (NCT01020357)
- Testing
- Caffeine citrate injection
- Where
- 4 sites in Australia, Canada
- Volunteers
- 201 people
- Sponsor
- McMaster University
Very Low Birth Weight Infants
Safety and Tolerability of Lactoferrin in Very Low Birth Weight Infants
To evaluate the safety and tolerability of three different lactoferrin doses in preterm infants
- Trial name
- NCT02731092
- Testing
- Lactoferrin
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Extremely Low Birth Weight
Humidity Strategy to Decrease Morbidity and Mortality in Extremely Low Birth Weight Infants
The purpose of this study is to apply a different incubator humidity strategy at birth to decrease morbidity and mortality in extremely low birth (1000 g or less) infants.
- Trial name
- NCT00850902
- Testing
- High Humidity (HH), Moderate Humidity
- Volunteers
- 700 people
- Sponsor
- King Fahad Medical City
Pregnancy, Weight Gain
Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women
This project will increase knowledge about how a simple intervention, grocery delivery, impacts weight gain and diet among low-income pregnant young women. Results can then be used to support other pregnant young women.
- Trial name
- NCT05000645
- Testing
- Grocery delivery, Unsweetened beverage delivery
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of Michigan
Premature Birth, Extreme Prematurity
The Pilot Experimental Study of the Neuroprotective Effects of Exosomes in Extremely Low Birth Weight Infants
To study the safety and efficacy of intranasal administration of exosomes derived from mesenchymal stromal cells on long-term neurodevelopmental outcome in extremely low birth weight infants born at gestational age 25/0-27/6…
- Conditions
- Premature Birth, Extreme Prematurity, Preterm Intraventricular Hemorrhage, Hypoxia-Ischemia, Cerebral
- Trial name
- NCT05490173
- Testing
- Exosomes derived from mesenchymal stromal cells (MSCs)
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare
Low Birth Weight Infants
Alkaline Phosphatase Level in Pregnancy and Its Association With Birth Weight
Alkaline phosphatase is known to be produced by syncytiotrophoblasts in the placenta and its levels are normally increased in pregnancy.
- Trial name
- NCT03187938
- Testing
- Testing of Alkaline Phosphatase Levels
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Hemodynamic Instability
Dobutamine Versus Placebo for Low Superior Vena Cava Flow in Newborns
Low systemic flow as measured by Doppler-echocardiography has been associated with poor neurological outcome. Yet, it has not been systematically evaluated whether the treatment of this hemodynamic condition is beneficial or not.
- Trial name
- NCT01605279
- Testing
- Dobutamine
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Adelina Pellicer
Bronchopulmonary Dysplasia, Very Low Birth Weight
Preterm Infant Inhaled Albuterol Dosing
The purpose of this study is to help determine the best dose of inhaled albuterol sulfate in premature babies at risk of developing bronchopulmonary dysplasia (BPD).
- Trial name
- NCT02447250
- Testing
- Varied albuterol dose response
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University