Clinical trials: Low-Level Laser Therapy
Genitourinary Syndrome of Menopause, Vaginal Atrophy
Vaginal Laser Therapy in Breast Cancer Survivors
This study evaluates the efficacy of vaginal CO2 laser therapy in breast cancer survivors with symptoms of Genitourinary Syndrome of Menopause.
- Conditions
- Genitourinary Syndrome of Menopause, Vaginal Atrophy, Breast Cancer, Dyspareunia
- Trial name
- NCT03738605
- Testing
- Microablative Fractional CO2 Laser Therapy
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Prostate Cancer, Low-risk or Favorable Intermediate Risk Prostate Cancer Who Are on an Active Surveillance Regimen
Investigator Initiated Trial to Further Evaluate the Safety and Efficacy of Trans-perineal Focal Laser Ablation of Localized Prostate Cancer Using High Frequency Micro-ultrasound Imaging
Trans-perineal focal laser ablation represents a promising alternative focal therapy option for patients with low-risk or favorable intermediate risk prostate cancer.
- Trial name
- NCT05826470
- Testing
- TRANBERG®|Thermal Therapy System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Genesis Research LLC
Postoperative Pain, Dental Implant
Laser Photobiomodulation After Dental Implant Surgery: A Comparison of 650 nm and 810 nm Diode Lasers
The goal of this clinical trial is to evaluate the effectiveness of laser light therapy, known as photobiomodulation (PBM), in reducing pain after dental implant surgery.
- Trial name
- NCT06988722
- Testing
- 650 nm Diode Laser PBM, 810 nm Diode Laser PBM
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Institute of Laser Enhanced Sciences
Chronic Shoulder Pain
The Effect of High-intensity Laser Therapy in Patients With Chronic Shoulder Pain
The aim of this study was to investigate the effects of biostimulating, analgesic and noninvasive high intensity laser therapy on pain, functionality and quality of life in patients with chronic shoulder pain.
- Trial name
- NCT05062941
- Testing
- Conventional physiotherapy, High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Head and Neck Cancer
The Management of RT-induced Hyposalivation Using LLLT
The primary purpose is to evaluate the effectiveness of photobiomodulation laser application in the management of patients with radiotherapy-induced hyposalivation.
- Trial name
- REACH-LLLT (NCT05538169)
- Testing
- low-level laser diode (Pioon Laser)
- Where
- Saudi Arabia
- Volunteers
- 10 people
- Sponsor
- King Saud University
Brain Tumor, Brain Tumor, Recurrent
Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors
The main purpose of this study is to evaluate the safety and performance of the AutoLITT system for the treatment of recurrent/progressive glioblastoma multiforme tumors (GBM).
- Conditions
- Brain Tumor, Brain Tumor, Recurrent, Brain Neoplasm, Brain Cancer
- Trial name
- NCT00747253
- Testing
- AutoLITT system
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Monteris Medical
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Mucositis Oral
Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young Adults
To assess the efficacy of preventive Low-Level Laser Therapy (LLLT) for reducing the incidence of WHO's grade 3-4 oral mucositis in children and young adults receiving chemotherapy regimens associated with a high rate of…
- Trial name
- MUCILA (NCT03983369)
- Testing
- Low-Level Laser Therapy
- Where
- 5 sites in France
- Volunteers
- 315 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Supraspinatus Tendinitis
HILT vs ESWT in Supraspinatus Tendinitis
This randomized controlled trial aims to compare the effectiveness of High-Intensity Laser Therapy (HILT) and Extracorporeal Shock Wave Therapy (ESWT) in patients with supraspinatus tendinitis.
- Trial name
- NCT07615920
- Testing
- High-Intensity Laser Therapy, Extracorporeal Shock Wave Therapy, Conventional Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
KERATOCONJUNCTIVITIS SICCA, XEROSTOMIA
Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome
This study was designed to test the efficacy and safety of low laser therapy to treat the xerostomia of patients with primary Sjogren's Syndrome.
- Conditions
- KERATOCONJUNCTIVITIS SICCA, XEROSTOMIA, SICCA SYNDROME, PRIMARY SJOGREN SYNDROME
- Trial name
- NCT02066896
- Testing
- Lasertherapy
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of São Paulo
Vulvar Lichen Sclerosus
Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser
Vulvar lichen sclerosus (VLS) is a lymphocyte-mediated disease of unknown etiology that can cause intense itching as well stenosis, hindering the evacuation and urination.
- Trial name
- VLSCBCPPTLIL (NCT02416531)
- Testing
- Clobetasol propionate, Photodynamic therapy, Low level laser therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Daniela de Fátima Teixeira da Silva
Knee Osteoarthritis
The Effectiveness of Low Level Laser Therapy on Particular Joint Points and Acupuncture Points on Knee Joints in Grade III Knee Osteoarthritis
LLLT is in use to treat different musculoskeletal condition. Osteoarthritis is one of the conditions needing LLLT for therapeutic effects.
- Trial name
- LLLT OA (NCT05403931)
- Testing
- Low level laser therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Universiti Teknologi Malaysia
Colles' Fracture
Low-level Laser Therapy in Wrist Fractures
Approximately 15,000 persons in Norway suffer from wrist fractures during a year, making it the most prevalent fracture in this country. Treated conservatively, a cast is used for 4-6 weeks before removal.
- Trial name
- NCT02749929
- Testing
- Low level laser therapy
- Where
- Norway
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Myofascial Pain, Trigger Points
Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain
Myofascial Pain is a clinical condition of myalgic pain characterized mainly by the presence of Myofascial Trigger Points. Trigger points can be active or latent and they are described as a hypersensitive spot within a taut band…
- Trial name
- NCT03375229
- Testing
- Dry Needling, Low-Level Laser Therapy
- Where
- Brazil
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Knee Arthritis Osteoarthritis
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis.
- Trial name
- HILT-CM (KOA) (NCT07551245)
- Testing
- High-Intensity Laser Therapy (HILT), Conventional Physical Therapy Modalities
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erbil Polytechnic University
Acute Coronary Syndrome
Class IV Laser Therapy on Ejection Fraction, Cardio Biomarkers and Functional Outcomes
A total of 60 Individuals with Acute coronary Syndrome who underwent angioplasty with or without stent will be recruited by purposive sampling method in a randomized double-blinded sham controlled trial.
- Trial name
- NCT05160519
- Testing
- Class IV Laser
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Asir John Samuel
Molar, Third, Low-level Laser Therapy
"Effectiveness of Dual-Wavelength Laser Therapy in Third Molar Extraction Pain, Swelling, and Trismus"
Objective: To investigate the effects of single session dual wavelength low dose laser therapy to be applied after third molar tooth extraction on postoperative pain, edema and physical activities.
- Trial name
- NCT05992233
- Testing
- Dual wavelength low level laser
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Non-curative Resectable Bile Duct Carcinoma
Single-arm Study of Photodynamic Laser Therapy Using Foscan for Non-curatively-resectable Bile Duct Carcinoma
The purpose of this study is to assess efficacy and safety of Foscan (temoporfin) photodynamic therapy in the treatment of locally advanced perihilar bile duct carcinoma without distant metastases.
- Trial name
- NCT01016002
- Testing
- Temoporfin
- Where
- 2 sites in Austria, Germany
- Volunteers
- 35 people
- Sponsor
- University of Salzburg
Hyperopia
Safety and Effectiveness Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Hyperopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of hyperopia, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762281
- Testing
- MEL 80 Hyperopic LASIK Treatment
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Onychomycosis
Study of Erchonia Low Level Laser Light Therapy to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser light therapy is effective in the treatment of toenail onychomycosis.
- Trial name
- NCT02242019
- Testing
- Erchonia LUNULA
- Where
- Ireland
- Volunteers
- 109 people
- Sponsor
- Erchonia Corporation