Clinical trials: Low-Level Laser Therapy
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoporosis
Effect of Class IV Laser Therapy and Pilates Exercises on Bone Density and Pain in Primary Osteoporosis: A Randomized Controlled Trial
the current study was to investigate the effect of class IV laser therapy and Pilates exercises on bone density in Osteoporosis.Sixty patients with osteoporosis (T-score values below -2.5) in lumbar spine with no evidence of…
- Trial name
- NCT04646863
- Testing
- laser therapy, exercise, combination
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Jaw, Edentulous, Partially
Pain Severity in Flapless Dental Implant Placement Using Laser
The goal of this split-mouth randomized clinical trial study was to investigate the effect of using a laser on pain and discomfort following flapless dental implant surgery.
- Trial name
- NCT06294249
- Testing
- Laser-induced Incision, Punch Incision, Implant Placement
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Metabolism Disorder
Metabolism Enhancement by Laser Therapy
This is a single-center, open-label pilot study to determine the effect of large area fractional laser treatment (LAFLT) on adults' metabolic profile.
- Trial name
- MELT (NCT06899958)
- Testing
- Fractional Laser
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Myofascial Pain Syndrome (MPS)
High-Intensity Laser Therapy for Trapezius Myofascial Pain (HILT-TRAP Study)
This study aims to evaluate the effectiveness of optimized High-Intensity Laser Therapy (HILT) compared with sham treatment in patients with trapezius myofascial pain syndrome.
- Trial name
- HILT-TRAP Stud (NCT07352787)
- Testing
- High-Intensity Laser Therapy
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- Neveen Abd El Maksoad Kohaf
Temporomandibular Joint Disorders
Clinical and Electromyographic Assessment of Occlusal Splint Therapy
Temporomandibular disorders (TMDs) cause pain and dysfunction in the masticatory system, often managed with occlusal splint therapy. However, splint therapy alone may yield inconsistent results.
- Trial name
- NCT07878247
- Testing
- Low Level Laser Therapy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Future University in Egypt
Phobias, Claustrophobia
Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training
There are two specific aims for this study. Aim 1 is to test whether low-level laser therapy (LLLT) can enhance the efficacy of fear extinction training in the modification of pathological fear.
- Conditions
- Phobias, Claustrophobia, Social Phobia
- Trial name
- NCT02926352
- Testing
- Extinction Training, Low-Level Laser Therapy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Burn Injury
Potential Benefits of Laser Treatment on Skin Blood Flow and Sweating in Burn Survivors
The purpose of this study is to examine effects of laser therapy on blood flow and sweating responses in burn-injured skin.
- Trial name
- NCT04947449
- Testing
- fractional CO2 laser
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Texas Southwestern Medical Center
Head and Neck Cancer, Lymphedema
Low-Level Laser in Head and Neck Chronic Lymphedema
The purpose of this study is to evaluate the effect of low-level laser treatment (LLLT) on the severity of lymphedema, symptom burden, functional status, and quality of life in HNC survivors.
- Conditions
- Head and Neck Cancer, Lymphedema, Fibrosis
- Trial name
- NCT04482855
- Testing
- Low-level laser
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Blood Flow Restriction Therapy, Neuromuscular Electrical Stimulation (NMES)
The Enhancement Effect of Low-Level Laser Therapy for Muscle Training with Combined NMES and BFR
Blood flow restriction training (BFR) with neuromuscular stimulation (NMES) is employed for individuals with limited mobility and joint issues.
- Conditions
- Blood Flow Restriction Therapy, Neuromuscular Electrical Stimulation (NMES), Laser Therapy, Low-Level, Muscle Strength
- Trial name
- NCT06739148
- Testing
- Low Level Laser Therapy, blood flow restriction, Neuromuscular Electrical Stimulation
- Where
- Taiwan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Actinic Keratosis
Comparative Study of Photodynamic Therapy vs. CO2 Laser Therapy in Treatment of Actinic Keratoses
The purpose of this study is to determine whether photodynamic therapy or CO2 laser therapy is superior in the treatment of actinic keratoses with respect to efficacy and side effects.
- Trial name
- NCT01481155
- Testing
- ablative CO2 laser therapy, photodynamic therapy
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Ruhr University of Bochum
Stroke
Low Level LASER Therapy in Chronic Stroke Patients With Spastic Planter Flexors.
Low-intensity LASER therapy on the spastic muscle, would result in improving muscle performance and improving the functional capacity of individuals under the exercises imposed by physical therapy.
- Trial name
- NCT05425225
- Testing
- Low level LASER therapy, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Diabetic Macular Edema
Laser vs Bevacizumab Injection Alone in Treatment of Diabetic Macular Edema
Currently, diabetic macular edema is treated is through injection of a medications such as off-label bevacizumab, which decreases the swelling in the retina.
- Trial name
- NCT02229175
- Testing
- bevacizumab, PASCAL Endpoint Management (EpM) laser treatment
- Where
- United States
- Sponsor
- University of California, San Francisco
Subacromial Impingement Syndrome, Shoulder Pain
High-Intensity Laser Therapy Versus Multimodal Physiotherapy in Subacromial Impingement Syndrome
This randomized controlled trial aimed to compare the short-term effectiveness of high-intensity laser therapy (HILT) and a multimodal physiotherapy program in patients with subacromial impingement syndrome (SIS).
- Conditions
- Subacromial Impingement Syndrome, Shoulder Pain, Rotator Cuff Disease
- Trial name
- NCT07586800
- Testing
- High-Intensity Laser Therapy, Multimodal Physiotherapy
- Volunteers
- 94 people
- Sponsor
- Tulay Yildirim
Stress Disorder, Sleep Disorder
Vascular Photobiomodulation on Sleep Qualityand Stress
Randomized clinical trial to evaluate the effect of vascular photobiomodulation on sleep quality, relaxation and stress when compared to placebo.
- Trial name
- NCT05415163
- Testing
- vascular photobiomodulation
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Nove de Julho
Crowding of Anterior Maxillary Teeth
Clear Aligner Treatment With and Without Low Level Laser Therapy for Upper Incisor Crowding
The goal of this clinical trial is to assess the effect of Low Level Laser Therapy (LLLT) on Upper Incisor Crowding using Clear Aligner Treatment (CAT).
- Trial name
- NCT06493721
- Testing
- Clear Aligner Treatment, Low level laser
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Chronic Fatigue Syndrome (CFS), Quality of Life
Photobiomodulation in Chronic Fatigue Syndrome
The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS).
- Trial name
- NCT07546539
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Rhinosinusitis
Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents
Chronic rhinosinusitis (CRS) is common disorder which affects up to 13% of the US population. CRS affects numerous Quality of Life (QOL) factors including smell, sleep and communication.
- Trial name
- NCT00948519
- Testing
- Laser + ICG, Laser only
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Low Back Pain
The RELIEF Study - Researching the Effectiveness of Lumbar Interventions for Enhancing Function
Low back pain (LBP) is one of the most common reasons for seeking medical care and accounts for over 3.7 million physician visits/year in the U.S. alone.
- Trial name
- NCT01854892
- Testing
- Manipulation, Mobilization, Laser Therapy
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Ohio University
Diabetic Foot Ulcer, Diabetic Foot
Use of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers
Diabetes mellitus (DM) is currently an important cause of morbidity and mortality. Global estimates indicate that 382 million people live with diabetes (8.3%), and that number could reach 592 million in 2035.
- Trial name
- NCT04246814
- Testing
- LG1, LG2, LG3
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Piaui