Clinical trials: Low-Level Laser Therapy
Knee Osteoarthritis
Combined Effect of Laser Acupuncture and Electroacupuncture in Knee Osteoarthritis Patients
Background: Knee osteoarthritis (KOA) is a common degenerative joint disorder affected 250 million people globally. It can not only result in disability, but also associated with cardiovascular disease and mortality.
- Trial name
- NCT04188925
- Testing
- Laser Acupuncture
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Lateral Epicondylitis, High Intensity Laser Therapy
High and Low Dose High-intensity Laser Therapy Lateral Epicondylitis
High-intensity laser therapy has gained increasing attention in recent years as a therapeutic modality. It is a non-invasive treatment that can reduce pain, increase local blood circulation, and promote tissue repair.
- Conditions
- Lateral Epicondylitis, High Intensity Laser Therapy, Tennis Elbow, High Intensity Laser
- Trial name
- NCT07342426
- Testing
- High intensity laser therapy, Infarred ray therapy system, Transcutaneous electrical nerve stimulator
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hypomineralization Molar Incisor
Laser Therapy and Flouride Therapy in Desensibilization Hypomineralized Teeth
To investigate the efficacy of laser therapy associated with fluorotherapy in the desensibitization of hypomineralized teeth in children 8 to 12 years of age. A randomized blinded clinical trial will be conducted.
- Trial name
- LTAFTIDHT (NCT03823170)
- Testing
- Laser therapy, Fluorotherapy, Laser therapy and Fluorotherapy
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Knee Osteoarthritis, Total Knee Replacement
The Effect of Laser Acupuncture Intervention to the Prognosis After TKR Surgery
This study protocol is mainly focus on the patients, who suffer pain, swelling, or range of motion limitation after total knee replacement (TKR) surgery procedure,would be relieved by use non-invasive laser acupuncture to stimuli…
- Trial name
- NCT05263856
- Testing
- laser acupuncture
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
DENT IMPLANTS, LASER
Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation
The purpose of this study is to compare clinical outcomes (change in bleeding sites (BOP) and probing depth reduction (PPD) after mechanical debridement of implant surfaces at sites exhibiting plaque induced inflammation with or…
- Trial name
- NCT04187053
- Testing
- Conventional mechanical therapy, Saline, Methylene Blue
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center, Houston
Prosthesis-Related Infections, Equipment Failure
Medico-economic Evaluation of Strategies for the Lead Extraction of Implantable Defibrillator and Pacemakers
The growing use and the expanding indications for cardiovascular implantable electronic devices (CIEDs) have been associated to an increase of device removal.
- Conditions
- Prosthesis-Related Infections, Equipment Failure, Heart Failure, Arrhythmias
- Trial name
- GAINE LASER (NCT03121183)
- Testing
- Laser sheath, Implantable Cardiac Device lead extraction
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Back Pain
Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients.
- Trial name
- NCT03859505
- Testing
- Active PBMT
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Universidade Cidade de Sao Paulo
Orthodontics, Periodontal Diseases
The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients
The aim of the study is to evaluate the effects of low-level laser therapy (LLLT) on patients with chronic periodontitis during a post-orthodontic period for 12 months. Following aspects will be assessed: 1.
- Trial name
- NCT03765151
- Testing
- low-level laser therapy, orthodontic retention
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The University of Hong Kong
Chronic Shoulder Pain
The Effect of High-intensity Laser Therapy in Patients With Chronic Shoulder Pain
The aim of this study was to investigate the effects of biostimulating, analgesic and noninvasive high intensity laser therapy on pain, functionality and quality of life in patients with chronic shoulder pain.
- Trial name
- NCT05062941
- Testing
- Conventional physiotherapy, High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Circumference Reduction
Study of the Combined Effect of Low Level Laser Therapy and Manual Lymph Drainage on Reducing Body Circumference
The purpose of this study is to determine whether low level laser light therapy applied using the Erchonia Verju Laser combined with manual lymph drainage applied using the Iskra Medical Green PRESS 8 Lymph Drainage System is…
- Trial name
- NCT02591056
- Testing
- Erchonia® Verju™ Laser, Green PRESS 8
- Where
- 3 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Stress Urinary Incontinence
IUL Study A Randomized Sham - Controlled Clinical Study
Primary aim of the study is to compare the impact of SUI on the VAS (visual analogue scale) 3 months after laser therapy versus sham laser therapy.
- Trial name
- NCT04707690
- Testing
- Intraurethral laser therapy
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cystocele, Pelvic Organ Prolapse
Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
The objective of the study is to retrospectively collect the data on patients who underwent pelvic organ prolapse treatment using a non-ablative Er:YAG laser with SMOOTH mode and to conduct an objective evaluation of safety and…
- Conditions
- Cystocele, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT04417413
- Testing
- Fotona ProlapLase
- Where
- Serbia
- Volunteers
- 41 people
- Sponsor
- Aleksandra Novakov Mikic
Pigmentation Disorder
Fractional Laser as Treatment Option for Various Pigment Disorders (Fractional-3)
The purpose of this study is to determine whether the use of non-ablative fractional laser is safe and effective in the treatment of melasma.
- Trial name
- NCT01085279
- Testing
- Fraxel Restore, Solta Medical Inc. (Non-ablative fractional laser), Modified Kligman's formula (Triple topical therapy)
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Netherlands Institute for Pigment Disorders
Scar
Comparison of the Efficacy of Fractional Er:YAG Laser for Acne Scar
Compare the efficacy of frational Er:YAG laser and that of bipolar frequency with diode laser treatment.
- Trial name
- NCT01958450
- Testing
- Er:YAG laser, Bipolar radiofrequency with diode laser
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cancer
Evaluate the Effectiveness of Low Level Laser Therapy (LLT) Combined With Acupuncture
evaluating The Investigational Therapy effects on quality of life, pain and patient's clinical status in adult cancer patients with solid tumors who are no longer candidates for active oncological therapies.
- Trial name
- NCT02686203
- Testing
- B-Cure Laser Pro and needles
- Volunteers
- 30 people
- Sponsor
- Erika Carmel ltd
Retinitis Pigmentosa (RP)
Subthreshold Micropulse Laser Therapy (SML) in Retinitis Pigmentosa
Introduction Retinitis pigmentosa (RP) is the most common form of genetic retinal degenerative disease. The disease is progressive and leads to blindness and permanent disability within a few years of diagnosis.
- Trial name
- NCT07088705
- Testing
- SML 577 nm, SML 810 nm
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Marta P. Wiącek
TMJ Disc Disorder
Comparison Between Splint and Laser in Patients Without Disc Displacement With Reduction
Stabilization splint therapy and Low-level laser therapy may serve as non-invasive intervention for painful temporomandibular disorders, but its efficacy is still debated.
- Trial name
- NCT05548894
- Testing
- stabilization splint, laser therapy, stabilization splint and laser therapy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
Myofascial Pain Syndrome
New Generation Low Level Laser Effect in Myofacial Pain Syndrome
Low level laser treatments have been used to treat painful trigger points in myofascial pain syndrome (MPS), but the effectiveness of the appropriate laser type and parameters is still uncertain.
- Trial name
- NCT06442553
- Testing
- GRR laser, Nd:YAG laser
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Lumbar Radiculopathy
Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy
To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.
- Trial name
- NCT06240845
- Testing
- High-level laser therapy, Low-level laser therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University