Clinical trials: Low-Level Laser Therapy
Depression, Depressive Disorder
Near-infrared Transcranial Laser Therapy in Subjects With Major Depressive Disorder
Major depressive disorder (MDD) is a leading cause of disability worldwide, and many patients do not achieve adequate benefit from current treatments.
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- ELATED-4 (NCT06934135)
- Testing
- Bilateral Near-Infrared Transcranial Photobiomodulation (tPBM)
- Where
- 2 sites in Peru
- Volunteers
- 50 people
- Sponsor
- NeuroThera DE
Malocclusion, Orthodontic Tooth Movement
Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction
Orthodontic treatment often requires moving the upper canine teeth (the pointed teeth) into the spaces left after removing premolar teeth.
- Conditions
- Malocclusion, Orthodontic Tooth Movement, Maxillary Canine Retraction
- Trial name
- MOP-PBMT (NCT07658235)
- Testing
- Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction
- Where
- Iraq
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kufa University
Overweight, Obese
Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
Currently in the United States about 97 million adults are considered obese, accounting for about 33% of the American adult population (compared to 22.9% in 1988).
- Trial name
- NCT02129608
- Testing
- LLLT, Lorcaserin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Posterior Tibial Tendon Insufficiency
Low-Level Laser Therapy and Orthotic Insole in Tibialis Posterior Tendon Insufficiency
The purpose of this study is to compare low-level laser therapy and insole interventions on pain, function and muscle strength in subjects with posterior tendon insufficiency.
- Trial name
- NCT03363074
- Testing
- Orthotic Insole, Low-Level Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Ulnar Nerve Entrapment at Elbow
Evaluation of the Efficacy of Low Level Laser Therapy in Ulnar Neuropathy at the Elbow
The purpose of this study is, to demonstrate the effectiveness of low-level laser therapy on symptoms, clinical and electrophysiological parameters in elbow ulnar neuropathy.
- Trial name
- NCT06086210
- Testing
- Low-level laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Gulsah Celik
Myofascial Pain Syndrome
Efficacy of Different Low Level Laser Therapy Sessions
Myofascial pain dysfunction syndrome is one of the common causes of non-odontogenic pain in the head and neck region. It accounts for 40-60% of the adult population.
- Trial name
- NCT06327204
- Testing
- 940-nm diode laser / one session, 940-nm diode laser / two session, 940-nm diode laser/ three session
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- October 6 University
Fatty Liver, Nonalcoholic, Liver Function
Enhanced Liver Function in Non-alcoholic Obese Fatty Liver Patients by Low Level Laser Therapy
Non-alcoholic fatty liver disease is excessive fat build-up in the liver with insulin resistance due to causes other than alcohol use.The obesity epidemic is closely associated with the rising prevalence and severity of…
- Trial name
- NCT04452409
- Testing
- low level laser, Mediterranean diet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Wound-healing
Low-Level Laser Therapy vs. Saline for Wound Healing After Primary Molar Extraction.
To evaluate the effect of low level laser therapy versus the saline on wound healing after extraction of primary Molars
- Trial name
- NCT06917599
- Testing
- Low-level laser, Saline Solution (NaCl 0,9%)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Levels of Pain
Effect of Low Level Laser Therapy on Pain Induced by Placement of Orthodontic Separators in Pediatric Patients
The primary goal of the study is to determine if there is a difference in pain levels following the use of low level laser therapy versus placebo and control after placement of elastomeric orthodontic separators in pediatric…
- Trial name
- NCT02211547
- Testing
- Epic 10 Diode Laser by Biolase Inc.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Skin Diseases
Laser Therapy Versus Narrow Band Ultraviolet B for the Treatment of Acne Vulgaris
Forty-five participants with facial AV were assigned randomly to three groups of fifteen subjects each. Each group received various therapies.
- Trial name
- LLLT-NBUB (NCT04254601)
- Testing
- Narrow band ultraviolet B., topical erythromycin cream 2% (Akne-Mycin- Egypt)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Hemodialysis
Low-Level Laser Therapy Versus Isometric Handgrip Exercise On Arteriovenous Fistula Maturation in Hemodialysis Patients
The purpose of this study is to evaluate the effectiveness of low-level laser therapy (LLLT) compared with isometric handgrip exercise and standard care in promoting vascular remodeling of arteriovenous fistulas (AVFs) among…
- Trial name
- NCT07787195
- Testing
- Low-level laser therapy, Isometric handgrip exercises, Standard postoperative care
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Dentofacial Deformity
Lower Laser Therapy in Orthognathics Surgery
This study will examine the use of lower laser therapy to reduce edema and pain in orthognathics surgery.
- Trial name
- NCT01530100
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Low-Level Laser Therapy
Therapeutic Effect of Intravascular Laser Irradiation of Blood
The investigators' previous studies results showed that the non-invasive treatment effects of low-energy lasers with the period of 5 consecutive days, could significantly improve the local function of static and dynamic motion…
- Trial name
- NCT03724799
- Testing
- Intravascular laser irradiation of blood for the patients with cerebral infarction
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Chronic Low-back Pain
The ECEALT Chronic Low Back Pain Study
The primary objective of this double-blind randomized control trial (RCT) is to evaluate the clinical effectiveness of LLLT as adjunctive therapy to standard exercise treatment in patients with non-specific chronic LBP.
- Trial name
- NCT05040633
- Testing
- BTL 4110 Smart Laser Therapy Equipment (BTL Industries Ltd, United Kingdom (UK)), Standard Exercise Therapy
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Health Rehab and Research Clinic
Dentin Sensitivity
Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may prevent dental sensitivity.
- Trial name
- NCT03044171
- Testing
- Low Level Laser Therapy, 1.1% Sodium Fluoride, In-office dental bleaching
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Leprosy Neuropathy
Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.
We are going to investigate leprosy patients with neuropathies. This problem can lead to changes in nerve function and lead to disability.
- Trial name
- NCT03072004
- Testing
- LLLT
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Federal University of Uberlandia
Chronic Pain
Low-level Laser Therapy in Patients With Chronic Fibromyalgia
The purpose of this study is to examine the use of low level therapeutic laser (LLLT) for its effects on pain, fatigue, and physical function in individuals with fibromyalgia.
- Trial name
- NCT02948634
- Testing
- Active Phoenix Laser Treatment
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Texas Southwestern Medical Center
the Presence of Subretinal Fluid (SRF)
Green Subthreshold Laser Therapy for Chronic Central Serous Chorioretinopathy.
Chronic Central Serous Chorioretinopathy (CSCR) is a vision-threatening retinal disorder characterized by persistent subretinal fluid due to choroidal vascular hyperpermeability and retinal pigment epithelium (RPE) dysfunction.
- Trial name
- NCT07020793
- Testing
- green subthreshold laser therapy
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Federico II University
Adhesive Capsulitis of Shoulder
HILT and US Therapies in Adhesive Capsulitis
Background: Adhesive capsulitis (AC) is a common musculoskeletal disease characterized by pain and limitation of movement in the shoulders of patients.
- Trial name
- NCT05210036
- Testing
- Ultrasound Therapy (US), High-Intensity Laser Therapy (HILT)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
TMD
Ozonated Olive Oil and Low-Level Laser Therapy in TMD Treatment
The aim of the present study was to determine the efficacy of ozonated olive oil and low-level laser therapy (LLLT) in treating pain in individuals with TMD.
- Trial name
- NCT05660343
- Testing
- Ozonized Olive Oil Solutions, Low Level Laser LLL Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University