Clinical trials: Low-Level Laser Therapy
Varicose Veins
The BRILLIANT Study
This trial was designed as a prospective, multi-center, randomized clinical trial of the FDA-cleared Vari-Lase Bright Tip Fiber compared to commercially available standard bare-tip laser fiber (control) to demonstrate the safety…
- Trial name
- BRILLIANT (NCT00618514)
- Testing
- Bright Tip Laser Fiber, Bare Tip Laser Fiber
- Where
- 7 sites in United States
- Volunteers
- 93 people
- Sponsor
- Vascular Solutions LLC
Diabetic Foot Ulcer
Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers (LLL&DIAB-03)
The global prevalence of diabetes is on the rise and with it increase in prevalence of diabetic foot ulcers (DFU). These recalcitrant wounds are difficult to manage and pose a heavy economic burden.
- Trial name
- NCT04796649
- Testing
- B-Cure laser pro
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Erika Carmel ltd
Diabetic Peripheral Neuropathy
Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain
The purpose of this study is to determine whether low level laser therapy is effective in the reduction of foot pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT02461225
- Testing
- Erchonia® FX-635™
- Where
- 2 sites in United States, Ireland
- Volunteers
- 30 people
- Sponsor
- Erchonia Corporation
Genitourinary Syndrome of Menopause
Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women
This is a prospective, multi-centre, double blinded, randomized controlled trial, which will be conducted under a common protocol.
- Trial name
- LASER_2022 (NCT05305209)
- Testing
- Intervention group, Control Group
- Where
- Spain
- Volunteers
- 189 people
- Sponsor
- University of Malaga
Striae; Albicantes
LLLT and Fractional CO2 Laser in the Treatment of Stria Alba
Stria alba (aka white or atrophic stretch marks) is a very common dermatologic condition that causes major psychological distress to those afflicted.
- Trial name
- NCT04165226
- Testing
- Low level light therapy, Fractional CO2, Combined fractional CO2 laser and low level light therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Primary Tooth Pulpotomy, Vital Pulp Therapy
Evaluation of the Success of TheraCal PT in Pulpotomy Treatment of Primary Teeth Using Low-Level Laser Therapy
This randomized clinical study aimed to compare the clinical and radiographic outcomes of TheraCal PT and Biodentine in pulpotomy treatment of primary teeth and to evaluate the influence of low-level laser therapy (LLLT) on…
- Trial name
- NCT07276685
- Testing
- Biodentine Pulpotomy, Low-Level Laser Therapy + Biodentine, TheraCal PT Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NECIBE DAMLA ŞAHIN
Bipolar Disorder
Oxygenating the Brain With Laser Therapy
Investigating the application of transcranial infrared laser stimulation in individuals with bipolar disorder.
- Trial name
- NCT05354895
- Testing
- Transcranial infrared laser stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Texas at Austin
COVID-19
Photobiomodulation Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease
The aim of this study is to evaluate the effectiveness of MLS laser therapy as a treatment for pulmonary complications due to COVID-19 infection.
- Trial name
- NCT04391712
- Testing
- MLS Laser, Regular Inpatient Medical Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lowell General Hospital
Orthodontic Appliance
Effect of Low Level Laser Therapy on Orthodontic Miniscrew Displacement
EFFECT OF LOW LEVEL LASER THERAPY ON ORTHODONTIC MINISCREW DISPLACEMENT
- Trial name
- Miniscrew (NCT05092633)
- Testing
- Miniscrew
- Where
- 2 sites in Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Back Pain, Obesity
Effect of Motor Control Exercise Combined With Laser Or TENS on Pain, Range of Motion, and Functional Disability on Obese Patients With Low Back Pain
This randomized study aimed to assess the impact of MCE in conjunction with LLLT and MCE in conjunction with TENS on pain levels, ROM, and functional disability in obese patients with LBP.
- Conditions
- Back Pain, Obesity, Motor Control Exercises, Laser Therapy
- Trial name
- NCT06545578
- Testing
- low-level laser therapy, TENS, motor control exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Tendinopathy
Efficacy of Therapeutic Percutaneous Electrolysis Simple vs Multiple vs Laser Therapy in Supraspinatus Tendinopathy.
Supraspinatus tendinopathy is one of the main pathologies that cause functional alterations in the glenohumeral joint. It reduces the quality of life of the population suffering from this injury.
- Trial name
- NCT07695792
- Testing
- Simple electrolysis percutaneous, Multifiliar Electrolysis percutaneus, Laser
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Pontificia de Salamanca
Scar, Laser Therapy
Treatment of Surgical Scars Using the Pulsed Dye Laser
The purpose of this study is to determine whether treatment of fresh surgical scars with a pulsed dye laser using purpura-inducing settings will improve clinical appearance better than one using non-purpura-inducing settings or…
- Trial name
- NCT00970671
- Testing
- Laser treatment with Purpuric settings, Laser treatment with Nonpurpuric settings, No treatment
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Diego
Healthy
Comparison of the Effects of Injectable Platelet-rich Fibrin and Low-dose Laser Applications on Palatal Wound Healing.
The investigators will evaluate the findings related to pain and bleeding, quality of life after surgery, and wound healing in participants who received injectable platelet-rich fibrin (i-PRF) and low-dose laser therapy to the…
- Trial name
- NCT06744270
- Testing
- i-PRF group, low-dose laser group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Esra Bozkurt
Healthy
Comparative Effect of High-Level Versus Low-Level Laser Therapy on Nerve Root Function Among Healthy Young Adults: A Randomized Controlled Trial
Study title: Comparative Effect of High-Level Versus Low-Level Laser Therapy on Nerve Root Function Among Healthy Young Adults: A Randomized Controlled Trial You are invited to participate in a research study to investigate the…
- Trial name
- NCT07260994
- Testing
- High-intensity laser therapy, Low-level laser therapy
- Where
- United Arab Emirates
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Taif A. M. Omran
Angle Class II
Which is Better Piezosurgery or Piezosurgery With Laser in Accelerating Orthodontic Tooth Movement
Sixty patients who need extraction-based treatment of the maxillary first premolars with subsequent retraction of the maxillary anterior teeth will be divided randomly into three groups: piezocision group, piezocision with…
- Trial name
- NCT05655169
- Testing
- Piezosurgery and GaALAs diode laser, Piezosurgery, Fixed orthodontic appliance
- Where
- Syria
- Volunteers
- 63 people
- Sponsor
- Damascus University
Circumference Reduction
Study of Low Level Laser Light Therapy on Circumference Reduction
The purpose of this study is to determine whether low level laser light therapy is effective in reducing circumference of the waist, hips, thighs and upper abdomen over a 6 week period.
- Trial name
- NCT02109107
- Testing
- Erchonia EZ6 Laser
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Radiation Dermatitis
Low Level Laser Therapy for Radiation Induced Dermatitis in H & N Squamous Cell Carcinoma
This study will assess the efficacy of LLLT to mitigate and ameliorate the acneiform-rash, radiation dermatitis, and pain, while assessing its impact on patient reported quality of life.
- Trial name
- NCT02384434
- Testing
- THOR Laser System for Low Level Laser Therapy (LLLT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Heath Skinner
Diabetes Mellitus, Type 2
Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy
The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms.
- Trial name
- NCT04436900
- Testing
- Panretinal Photocoagulation (PRP)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Baqiyatallah Medical Sciences University
Laser Effect Around Dental Implant
Evaluation of the Effect of Low Level Laser Therapy on Crestal Bone Changes and Secondary Stability Around Delayed Implant
Although implant survival and success rates are prominent, there is still progress to be made in both survival and success rates, as well as in improving implant stability at implant placement in order to accomplish…
- Trial name
- NCT06666062
- Testing
- implant placement and low level laser therapy, implant placement
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Lina Amr Talaat
Low Level Laser Therapy, Canine Retraction
Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
- Conditions
- Low Level Laser Therapy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- NCT05811728
- Testing
- Low level laser therapy, without beam emission
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly