Clinical trials: Low-Level Laser Therapy
Head and Neck Neoplasms
Evaluation of Two Methods of Administration of Photobiomodulation in the Context of the Prevention and Treatment of Mucositis Induced by Radiotherapy, During the Treatment of Head and Neck Cancers
The aim of this feasibility, prospective, single-center trial is to compare an intra-oral Photobiomodulation (PBM) via the Caremin650TM device (NeoMedLight) and a transcutaneous PBM via the ATP 38® device (Swiss Bio Innov) in…
- Trial name
- RADIO-PBM (NCT06458517)
- Testing
- Photobiomodulation session - intraoral, Photobiomodulation session - transcutaneous
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Paul Strauss
Aggressive Periodontitis, Generalized
Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
The aim of this project is to compare the efficacy and the local effect of the association of single or repeated application of photodynamic therapy (PDT) with antibiotic agents using Amoxicillin + Metronidazole or Clarithromycin…
- Trial name
- NCT03132714
- Testing
- Full-mouth ultrasonic debridement, Amoxicillin 500mg, Metronidazole 400mg
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Diabete Type 2, Diabetic Foot Ulcer
Effects and Feasibility of Photobiomodulation at 830nm Nanometers in the Treatment of Diabetic Ulcers
Diabetic foot ulcers (DFU) are among the late complications of DFU, defined as skin lesions that involve the dermis to deeper structures, such as muscles and bones.
- Conditions
- Diabete Type 2, Diabetic Foot Ulcer, Photobiomodulation, Low Level Laser Therapy
- Trial name
- NCT07043868
- Testing
- Low Level Laser Therapy
- Volunteers
- 136 people
- Sponsor
- Federal University of Piaui
Overweight, Obese
Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
Currently in the United States about 97 million adults are considered obese, accounting for about 33% of the American adult population (compared to 22.9% in 1988).
- Trial name
- NCT02129608
- Testing
- LLLT, Lorcaserin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetic Foot Ulcer
Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds
This is a randomized, double blind, placebo-controlled study to evaluate the safety of the low level laser MC-8XL device treatment in subjects with an unsuccessfully treated Diabetic Foot Ulcer (DFU) that has been present for at…
- Trial name
- NCT03204149
- Testing
- MC-8XL low level laser device and Standard wound care
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Medical Coherence LLC
Healthy
Use of Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance
The study hypothesis is a improved muscle fatigue resistance induced by low-level laser therapy applied between sets of intense exercises.
- Trial name
- NCT01972100
- Testing
- Low-level laser therapy (808nm), isokinetic exercise
- Where
- Brazil
- Volunteers
- 7 people
- Sponsor
- Cleber Ferraresi
Carpal Tunnel Syndrome (CTS)
Low-Level Laser Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy, caused by compression of the median nerve within the carpal tunnel at the wrist.
- Trial name
- NCT07788248
- Testing
- Low-Level Laser Therapy (LLLT), Paraffin Bath Therapy, Standard Conservative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Knee Osteoarthritis
HILT Dose Optimization for Knee Osteoarthritis Pain
This study aims to find the best settings (dose) for High-Intensity Laser Therapy (HILT) to reduce pain and improve function in people with moderate knee osteoarthritis.
- Trial name
- NCT06916676
- Testing
- Low-Dose High-Intensity Laser Therapy (10 J/cm²), Medium-Dose High-Intensity Laser Therapy (15 J/cm²), High-Dose High-Intensity Laser Therapy (20 J/cm²)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al Hayah University In Cairo
Disk Herniated Lumbar
Compare Effects of Ultrasound Therapy With High Intensity Laser Therapy for Treatment of Lumbar Disc Herniation.
The aim of this study is to assess and compare the effects of ultrasound therapy and High Intensity Laser Therapy, as the treatment option in case of lumbar disc herniation.
- Trial name
- NCT05261815
- Testing
- Ultrasound Therapy, High Intensity Laser Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Acceleration of Tooth Movement
The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement and Reducing Pain During Orthodontic Treatment
Orthodontic treatment is a common and effective approach to correcting dental malocclusions and improving oral function and aesthetics.
- Trial name
- LLLT (NCT07591948)
- Testing
- Low level laser therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Cystocele, Pelvic Organ Prolapse
Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
The objective of the study is to retrospectively collect the data on patients who underwent pelvic organ prolapse treatment using a non-ablative Er:YAG laser with SMOOTH mode and to conduct an objective evaluation of safety and…
- Conditions
- Cystocele, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT04417413
- Testing
- Fotona ProlapLase
- Where
- Serbia
- Volunteers
- 41 people
- Sponsor
- Aleksandra Novakov Mikic
Skin Aging
Reduction in Symptoms After Laser Therapy With Acorn aHFS
This study evaluates the severity and duration of symptoms experienced after laser therapy comparing four post-procedure topical products.
- Trial name
- NCT06336135
- Testing
- autologous hair follicle derived secretome
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Osteoarthritis, Knee
Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis
This randomized, double-blind, sham-controlled clinical trial evaluated the effectiveness of high-intensity laser therapy (HILT) in patients with early-stage symptomatic knee osteoarthritis.
- Trial name
- HILT-ESCOA (NCT07859878)
- Testing
- High-Intensity Laser Therapy (HILT), Standardized Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ege University
Pelvic Floor Disorders, Vaginal Atrophy
Effect of Laser Therapy on Vaginal Tissue
Pelvic floor disorders, including prolapse, incontinence, and vulvovaginal atrophy decrease the quality of life of every fourth woman.
- Trial name
- NCT05898191
- Testing
- vaginal laser treatment
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Hemodialysis
Efficacy of of Acupuncture Laser Therapy on Hemodialysis Patients
This expected prospective randomized control trial study will involve 60 haemodialysis patients with neck pain. The patients in the experimental group (E) will subject, medical treatment besides acupuncture laser therapy.
- Trial name
- NCT07099352
- Testing
- Acupuncture Laser Therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sinai University
Impacted Mandibular Third Molar Extraction
Effect of Titanium-Prepared Platelet-Rich Fibrin and Low-Level Laser Therapy on Postoperative Morbidity After Mandibular Third Molar Surgery
This randomized double-blind clinical trial aims to evaluate the effects of titanium-prepared platelet-rich fibrin (T-PRF), low-level laser therapy (LLLT), and their combination on postoperative outcomes following surgical…
- Trial name
- NCT07748585
- Testing
- Titanium-Prepared Platelet-Rich Fibrin (T-PRF), Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Sacroiliac Joint Pain
Efficacy of Adding LLL Therapy to Postural Correction Exercises on Postnatal SIJ Pain
the purpose of the study will be to to examine the effect of low level laser therapy on pain and function disability in postnatal women with sacroiliac joint pain.
- Trial name
- NCT05306236
- Testing
- LLL therapy , postural correction ex
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Carcinoma, Cancer Survivor
Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia
- Trial name
- NCT03307044
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Periodontal Disease
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: a Relation to Periodontal Inflammaging
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
- Trial name
- NCT06677736
- Testing
- conventional scaling and debridement, Diode laser as adjunctive to conventional scaling and debridement
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Rawda Saleh Saad Alashmawy
Forward Head Posture
High Intensity Laser Therapy Versus Scapular Stabilization Exercises on Ventilatory Function in Forward Head Posture
The purpose of the study is to compare between the efficacy of high intensity LASER therapy and scapular stabilization exercises on ventilatory functions in forward head posture patients
- Trial name
- NCT06270563
- Testing
- Postural advice, Traditional exercise treatment, Scapular stabilization exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University