Clinical trials: Low-Level Light Therapy
Adhesive Capsulitis of Shoulder
Using Large-area Low-level Light Therapy for Treating Adhesive Capsulitis of the Shoulder
Adhesive capsulitis, is a common problem characterized by the insidious onset of glenohumeral pain and limitation of shoulder motion in all planes.
- Trial name
- NCT06004609
- Testing
- Low-level laser therapy (LLLT), Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Respiratory Failure
Effects of PBMT-sMF in Mechanically Ventilated Patients
The goal of this clinical trial is to evaluate the effectiveness of photobiomodulation therapy combined with static magnetic field (PBMT-sMF) in adult patients who require mechanical ventilation.
- Trial name
- NCT06454006
- Testing
- Active PBMT-sMF
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- University of Nove de Julho
Pain Management, TKA
Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study
A pilot study to assess the efficacy and feasibility of PBMT for pain control in patients undergoing a TKA and are discharged the same day from an ambulatory surgery center.
- Conditions
- Pain Management, TKA, Post Operative Analgesia, Low Level Laser Therapy
- Trial name
- NCT07750912
- Testing
- LightForce XLI
- Volunteers
- 15 people
- Sponsor
- Mohammad Burney, MD
Wound Heal, Vestibular Abnormality
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional…
- Conditions
- Wound Heal, Vestibular Abnormality, Low-level Light Therapy, Surgical Wound
- Trial name
- NCT05252260
- Testing
- Diode Laser, Conventional Surgery, Low level laser therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Photobiomodulation, Dental Hypersensitivity
Evaluation of Tooth Sensitivity After Scaling and Root Planing Treated With Photobiomodulation
One hundred twenty patients with dentin sensibility after non-surgical scaling and root planning (SRP) will be randomly included in 2 groups: Experimental Group: SRP+ Photobiomodulation (PBM) (660nm, 100W, area 0,5cm2, 200w/cm2…
- Trial name
- NCT05946265
- Testing
- Photobiomodulation, simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- University of Nove de Julho
Dermatitis
Use of Low-level Laser Therapy in the Treatment of Incontinence-associated Dermatitis in the Elderly
Incontinence-associated dermatitis (IAD) is defined as skin inflammation resulting from prolonged exposure to feces and/or urine, found in individuals with urinary incontinence, fecal incontinence, or both.
- Trial name
- NCT05699122
- Testing
- Gentle intimate hygiene and skin protective barrier application - Persistent erythema with intact epidermis, Gentle intimate hygiene and skin protective barrier application - Erythema with signs of epidermis loss, Low Level Laser Therapy - Persistent erythema with intact epidermis
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Myopia, Repeated Low-level Red Light
Real-world Registry Study of Red Light Treatment on Myopia Control: a Focus on Non-responders to Conventional Treatments
This real-world observational registry study aims to assess the effectiveness of Repeated Low-Level Red Light (RLRL) therapy in controlling myopia progression among children aged 8 to 16 who have not responded to conventional…
- Trial name
- NCT06569810
- Testing
- Repeated Low-Level Red Light (RLRL) therapy
- Volunteers
- 2,500 people
- Sponsor
- The Hong Kong Polytechnic University
Oral Mucositis
Prevention of Oral Mucositis Using Photobiomodulation Therapy
Oral mucositis is a significant and common toxicity experienced by patients who receive high-dose chemotherapy as a preparatory regimen for a hematopoietic cell transplant (HCT).
- Trial name
- NCT04227340
- Testing
- Photobiomodulation Therapy (PBM), Pain and Oral Function Assessment, Parent-Reported Satisfaction Survey
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- St. Jude Children's Research Hospital
Chemotherapy-induced Alopecia
Photobiomodulation Therapy in the Prevention and Management of Chemotherapy-Induced Alopecia
This study aims to investigate the effectiveness of photobiomodulation therapy (PBM) in the prevention and management of chemotherapy-induced alopecia (CIA).
- Trial name
- HairLight (NCT05177289)
- Testing
- Theradome® LH80 pro, Scalp cooling
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Jessa Hospital
Ulcerative Colitis, Proctitis
Assessment of Photopill Capsule Treatment for Safety and Feasibility in Ulcerative Proctitis
Low Level Light therapy (LLLT) has been used for tissue healing in many mucosal diseases that involve wounds, ulcers and inflammation, oral chemotherapy-induced mucositis in particular.
- Trial name
- Photopill (NCT01837615)
- Testing
- Photopill treatment
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Myopia
Study on Safety and Efficacy of Focused LED-Based Red-Light Therapy in Myopic Adults
This research project is a prospective, single-arm, open-label pilot study designed to evaluate the efficacy and safety of focused LED-based repeated low-level red-light (fLED-RLRL) therapy in myopic adults.
- Trial name
- NCT07369804
- Testing
- fLED-based red-light therapy
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The Hong Kong Polytechnic University
Muscle Fatigue
Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue
800-nm laser light has been shown to delay muscle fatigue when applied before exercise. The effect of illumination during the aerobic phase of strenuous exercise has not been studied.
- Trial name
- NCT03461731
- Testing
- Control, 800 nm laser, combination laser
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- College of Charleston
Healing Surgical Wounds, Pain Measurement
Effects of Laser Stimulation on Wound Healing of Human Palatal Tissue
The purpose of this study is to assess the effects of photobiomodulation (PBM) with an Er:YAG laser on the palatal donor site following subepithelial connective tissue graft (SECTG) surgery.
- Trial name
- NCT03741062
- Testing
- J. Morita AdvErl Evo Er:YAG laser, Control
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Intraventricular Hemorrhage of Prematurity, Hydrocephalus
Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4
The primary purpose of this study is to serve as a pilot study of the EFIL device treatment feasibility of IVH grades 3,4 to guide development of a larger trial.
- Trial name
- EFIL (NCT06797219)
- Testing
- Low Level Laser Therapy for Intraventricular Hemorrhage of Prematurity
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Dry Eye Disease (DED)
Photobiomodulation in Combination With Topical Cyclosporine A or Tacrolimus
The objective of the study is to evaluate the effectiveness of Low-level light therapy (LLLT) in combination with either topical Cyclosporine A (CsA) or topical Tacrolimus, using each non-steroidal immunosuppressant as an active…
- Trial name
- NCT07239128
- Testing
- Low-level light therapy (LLLT), Topical Cyclosporine A, Topical tacrolimus
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- University of Seville
Circumference Reduction
Study of Low Level Laser Light Therapy on Circumference Reduction
The purpose of this study is to determine whether low level laser light therapy is effective in reducing circumference of the waist, hips, thighs and upper abdomen over a 6 week period.
- Trial name
- NCT02109107
- Testing
- Erchonia EZ6 Laser
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Red Laser Light-Induced Retinopathy of Both Eyes (Diagnosis)
Fundus Effects of Repeated Low-Level Red-Light Therapy in Chinese Myopic Minors: A Randomized Controlled Clinical Trial
1. Research Objective: The primary objective is to investigate the short-term effects of repetitive low-intensity red light therapy on the fundus of the eyes of underage individuals with myopia. 2.
- Trial name
- NCT06034912
- Testing
- Low-Intensity Red Light Therapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Lasers, Resistance Training
Photobiomodulation (PBM) Therapy on Muscle Performance in Elderly Women
The present project aims to investigate the acute and chronic effects of laser photobiomodulation (PBM) at 808 nm on muscle performance in physically active elderly women.
- Conditions
- Lasers, Resistance Training, Muscle Strength, Aged
- Trial name
- NCT04241991
- Testing
- Active laser
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Healthy
Effects of Phototherapy by Low-level Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical, Biomechanical, Histologic and Genetic Responses of Muscle Performance of Young Males Submitted to Physical Strength Training
Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, light-emitting diode therapy (LEDT) has been used to improve muscle performance in experimental models and human…
- Trial name
- NCT01770938
- Testing
- Effective light-emitting diode therapy
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Mild Cognitive Impairment (MCI), Amyloid Pathology
Using Light Therapy for Mild Cognitive Impairment
The goal of this clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and…
- Trial name
- LTMC (NCT07651787)
- Testing
- Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Oklahoma