Clinical trials: Low-level Laser Therapy
Infertility
Effect of Low Level Laser Therapy on Endometrial Cells: An In Vitro Study
The human endometrium is an extremely sensitive target. LLLT can enhance the proliferation rate of various cell lines, it produces higher rates of ATP, RNA, and DNA synthesis in stem cells and other cell lines.
- Trial name
- LLLT (NCT02764034)
- Testing
- Low level Laser diode machine
- Where
- Egypt
- Sponsor
- Cairo University
HPV-Related Cervical Carcinoma, Low-Grade Squamous Intraepithelial Lesions
Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection
Non-RCT clinical trial comparing 5-ALA photodynamic therapy and CO2 laser for persistent high-risk HPV-related low-grade cervical lesions.
- Conditions
- HPV-Related Cervical Carcinoma, Low-Grade Squamous Intraepithelial Lesions, HPV Infection, Photodynamic Therapy
- Trial name
- NCT06052033
- Testing
- CO2
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Plantar Fascitis
Low-Level Laser Therapy for Plantar Fasciitis
Plantar fasciitis (PF), a degenerative injury of the connective tissue in the foot, results in pain-related disability in Service Members and contributes to decreased physical activity and excessive healthcare costs.
- Trial name
- NCT05763381
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- The Geneva Foundation
Periodontal Disease
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: a Relation to Periodontal Inflammaging
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
- Trial name
- NCT06677736
- Testing
- conventional scaling and debridement, Diode laser as adjunctive to conventional scaling and debridement
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Rawda Saleh Saad Alashmawy
Osteoarthritis, Knee
Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis
This Phase I study is being conducted to examine the efficacy of the Light Sciences LLC (LSLLC) phototherapy device for home (self) treatment of knee osteoarthritis (OA).
- Trial name
- NCT00375544
- Testing
- Low level light therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Light Sciences LLC
Sacroilitis
Efficacy of Extracorporeal Shock Wave Therapy, LASER Therapy and Cryotherapy in Patients Having Sacroiliitis
This research aimed to determine the effect of extracorporeal shock wave therapy, LASER therapy and cryotherapy on PPT, Pain and functional disability in patients having Sacroiliitis.
- Trial name
- NCT06569615
- Testing
- shock wave therapy, LASER Therapy, Cryotherapy
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Najran University
Postoperative Facial Nerve Dysfunction
Comparison of Two Photobiomodulation Systems for Facial Nerve Dysfunction Following TMJ Surgery
This randomized clinical trial compared two photobiomodulation systems for the management of postoperative facial nerve dysfunction following temporomandibular joint surgery.
- Trial name
- NCT07771933
- Testing
- GRR Laser Photobiomodulation System, SiroLaser Advance Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara University
Low Back Pain
LLLT to Reduce Low Back Pain
The purpose of this research study is to gather information on the effectiveness of the Trident low-level laser therapy (LLLT) in combination with clinical patient education manuals to reduce lower back pain.
- Trial name
- NCT06007976
- Testing
- Erchonia® Trident
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Baldness
Impact of Low-Level Laser Therapy on Hair Regrowth Post PRP Treatment
Low-level laser stimulates cells in the hair follicles, which promotes hair growth. The patient's own blood platelets are used in platelet-rich plasma treatment to encourage hair growth.
- Trial name
- NCT07048626
- Testing
- PRP treatment, low level laser therapy post prp treatment
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Superior University
Prostate Cancer, Low-risk or Favorable Intermediate Risk Prostate Cancer Who Are on an Active Surveillance Regimen
Investigator Initiated Trial to Further Evaluate the Safety and Efficacy of Trans-perineal Focal Laser Ablation of Localized Prostate Cancer Using High Frequency Micro-ultrasound Imaging
Trans-perineal focal laser ablation represents a promising alternative focal therapy option for patients with low-risk or favorable intermediate risk prostate cancer.
- Trial name
- NCT05826470
- Testing
- TRANBERG®|Thermal Therapy System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Genesis Research LLC
Orthodontic Appliance Complication
Low Level Laser Therapy Applied in Orthodontic Tooth Movement
Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time.
- Trial name
- NCT05695053
- Testing
- Low Level Laser Therapy
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Temporomandibular Disorder
Standard Care With LLLT & Myofascial Release Versus Standard Care Alone in Pregnant Women With Temporomandibular Disorder
This study will investigate a novel approach to treat pregnant women with tempromandibular disorder using a combined method of low level laser therapy, myofascial release and standard care versus standard care alone.
- Trial name
- NCT05138354
- Testing
- Low Level laser therapy, Myofascial release, Standard care
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Plantar Fascitis, Achilles Tendon Pain
Effect of HILT vs LLLT in Treatment of Patients With Achilles Tendinitis or Plantar Fasciitis
The aim of this study is to evaluate and compare the changes of heel pain, functional health and well-being after high-intensity and low-level laser therapy for plantar fasciitis or Achilles tendinopathy
- Trial name
- NCT03873961
- Testing
- High-intensity laser therapy, Low-level Laser therapy
- Where
- Lithuania
- Volunteers
- 155 people
- Sponsor
- Lithuanian University of Health Sciences
Pain Threshold, Pain Tolerance
Acute Effects of LLLT on Pain Threshold and Pain Tolerance
Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser…
- Conditions
- Pain Threshold, Pain Tolerance, Acute Pain, Low-level Laser Therapy
- Trial name
- NCT07422272
- Testing
- Low-Level Laser Therapy (LLLT)
- Where
- Cyprus
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- European University of Lefke
Obstructive Sleep Apnea
Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea
This study was conducted on 26 patients with obstructive sleep apnea. The patients were divided randomly and equally into two equal groups.
- Trial name
- NCT06427161
- Testing
- LLLT application, dextrose injection
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Mansoura University
Lentigo, Hyperpigmentation
Efficacy and Tolerance of D-pigment Versus Moisturizer in Hands' Lentigo Lesions With or Without Laser Therapy
Pierre Fabre Dermo-Cosmétique has commercialized a cosmetic product (D-pigment rich texture) for treatment of hyperpigmentation.
- Trial name
- NCT03457246
- Testing
- D-Pigment rich texture, Hydrance optimale riche
- Volunteers
- 40 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Laser Therapy, Exosomes
Enhancing Skin Rejuvenation Using Laser and Exosomes
Enhancing Skin Rejuvenation A Single-Blind, Randomized Control Study on the Combined Efficacy of Aerolase 1064 nm YAG Laser and Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells
- Trial name
- NCT07281690
- Testing
- 1064-nm Nd:YAG Laser Treatment, Topical Umbilical Cord-Derived Exosomes (UC-MSC Exosomes)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laser Beamer Skincare
Diabetic Foot Ulcer (DFU)
Low-level Laser Therapy Versus Offloading Exercises on Foot Ulcer Healing in Patients with Type 2 Diabetes
The goal of this clinical trial is to evaluate the effect of extravascular Low-level laser therapy (LLLT) versus offloading exercises on foot ulcers healing (DFUs) in type 2 diabetic patients.
- Trial name
- NCT06670417
- Testing
- Low level laser therapy watch: The laser watch device was a semiconductor LLL therapeutic apparatus, (model:SL-03 GaALAs semiconductor) Domer Laser Therapy Watch class 3B 650nm low-level laser light, Buerger Allen exercise, Regular wound care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Wound - in Medical Care
Evaluation of Skin Stiffness Changes in Wounds Before and After Low-Level Laser Therapy
Chronic wounds and impaired healing remain a major clinical challenge, particularly in patients with diabetes, vascular disease, or age-related skin fragility.
- Trial name
- NCT07177274
- Testing
- Low Level Laser Therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Asia University