Clinical trials: Lower Back Pain, open to volunteers
Chronic Low-back Pain, Herniated Disc
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
The study is a post-market surveillance study of the Lumbar Implant for Stiffness Augmentation (LISA), a medical device, which is used to treat low-back pain that accompanies degenerative lesions of grades II, III, and IV…
- Conditions
- Chronic Low-back Pain, Herniated Disc, Degenerative Disc Disease, Lumbar Canal Stenosis
- Trial name
- LISA-PMCF (NCT04631133)
- Testing
- Lumbar Implant for Stiffness Augmentation (LISA)
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 136 people
- Sponsor
- BACKBONE
Low Back Pain
Graston Versus Active Release Technique in Females With Non Specific Low Back Pain
Non-specific Low Back Pain defined by tension, soreness, and/or stiffness of the lower back with unknown origins of pain. Reduction in hamstrings flexibility has found to be one of the causes for development of low back pain.
- Trial name
- NCT06877767
- Testing
- Graston Technique, Active Release Technique
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
TECAR Therapy, Low Back Pain
TECAR Therapy and Chronic Low Back Pain
The goal of this clinical trial is to learn whether adding TECAR therapy to traditional physiotherapy is more effective than traditional physiotherapy alone for reducing pain and functional disability and improving physical…
- Trial name
- NCT07825298
- Testing
- Control Group, TECAR therapy
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Cairo University
Low Back Pain
Massage Therapy for Healthcare Staff
The piriformis muscle can be a contributing factor to low back pain (LBP) due to its anatomical proximity to the sciatic nerve and sacroiliac joint.
- Trial name
- NCT07094997
- Testing
- Guidline-basaed massage therapy, Swedish massage
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Chronic Low-back Pain, Back Disorder
Movement Performance in Persons With Chronic Back Pain
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance…
- Trial name
- NCT06891625
- Testing
- SMT, ET, OLP
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Chronic Non-Specific Low Back Pain, Low Back Pain
Comparison of Traditional, Synchronous, and Asynchronous Telerehabilitation in Office Workers With Chronic Nonspecific Low Back Pain
Chronic Nonspecific Low Back Pain (NLBP) is a common condition that occurs without a specific underlying pathology, resulting in muscle tension, pain, and a decreased quality of life.
- Trial name
- NCT07700589
- Testing
- Face-to-Face Clinic-Based Exercise, Synchronous Telerehabilitation Exercise, Asynchronous Telerehabilitation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Aydın University
Acute Back Pain, Emergency Department Patient
Treatment of Acute Low Back Pain With Transcutaneous Electrical Neurostimulation at the Emergency Department: a Randomized Controlled Trial
Acute low back pain is a frequent cause of emergency department admissions (4.39% [95% CI: 3.67-5.18])1. Drug therapeutic options are limited and ineffective.
- Trial name
- TENS BACK PAIN (NCT07183176)
- Testing
- Chattanooga CEFAR Tens
- Volunteers
- 250 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Chronic Nonspecific Low-back Pain, CNSLBP
Effects of Virtual Reality Exergames Versus Spinal Manipulation in Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to compare the acute effects of virtual reality exergames (VR-EXG) and spinal manipulation on pain, kinesiophobia, mood states, functional disability and lumbar range of motion in individuals…
- Trial name
- NCT07876960
- Testing
- Virtual Reality, Spinal manipulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Lumbosacral Radiculopathy, Sciatica
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy.
- Conditions
- Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar
- Trial name
- Move-MORE (NCT07125027)
- Testing
- Move-MORE
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Low Back Pain, Back Pain
Acute Effects of Hot-Pack Therapy in Low Back Pain
This single-centre, parallel-group randomized controlled trial will test whether one session of moist hot-pack therapy produces immediate improvements in pain intensity and lumbar erector spinae muscle stiffness in adults with…
- Trial name
- HOTPACK-LBP (NCT07242183)
- Testing
- Hot-Pack
- Volunteers
- 24 people
- Sponsor
- Erzurum Technical University
Low Back Pain
PNF Technique on Iliopsoas and Hamstring Muscle on Chronic Low Back Pain
The aim of the study to evaluate the effects of PNF in terms of decreasing low back pain, increasing range of motion and improving flexibility of the hamstrings and iliopsoas.
- Trial name
- NCT06656156
- Testing
- Proprioceptive neuromuscular facilitation technique, Conventional treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Acute Non-specific Low Back Pain
Kinesiology Taping in Patients With Acute Low Back Pain
This prospective, randomized controlled trial will investigate the effectiveness of adding Kinesiology Taping (KT) to a standard physiotherapy program in individuals with acute non-specific low back pain.
- Trial name
- Taping (NCT07731269)
- Testing
- kinesiologic taping, standard physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Rumeli University
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Chronic Low-back Pain, Vertebrogenic Pain Syndrome
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
Compile real-world outcomes of commercially approved Intracept™ Intraosseous Nerve Ablation Systems in the treatment of patients diagnosed with vertebrogenic pain.
- Trial name
- IMPROVE (NCT06827262)
- Testing
- Intracept™ Intraosseous Nerve Ablation
- Where
- 22 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Scientific Corporation
Chronic Low Back Pain (CLBP)
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure.
- Trial name
- ASTRAL (NCT07222462)
- Testing
- Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Lower Back Pain, Obesity (BMI>30)
Semaglutide for Low Back Pain
Low back pain is the leading cause of disability in the United States, and obesity is a major risk factor for its development. GLP-1 receptor agonists such as Semaglutide have emerged as effective weight loss agents that may also…
- Conditions
- Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 Agonist
- Trial name
- NCT07731256
- Testing
- Semaglutide (administered by PDS290 pen-injector)
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Washington University School of Medicine
Chronic Low Back Pain
Effect of Passive Versus Active Aquatic Therapy Compared With Conventional Physiotherapy for Chronic Low Back Pain
This study is designed to help people with chronic low back pain, which is pain in the lower back that persists for more than three months and can affect daily life, including sitting, standing, walking, lifting, and other…
- Trial name
- AQUA-LBP (NCT07196826)
- Testing
- Active Aquatic Therapy, Passive Aquatic Therapy, Conventional Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 12 people
- Sponsor
- Gulf Medical University
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki