Clinical trials: Lower Extremity Amputation, open to volunteers
Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation
People with leg amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb problems like pain or skin breakdown.
- Trial name
- NCT05124652
- Testing
- Auto Adjusting Prosthesis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
Amputation of Lower Extremity, All Causes
Gait and Energy Expenditure in Children With Lower Limb Amputation (MAPEDE)
In lower limb amputation, prosthetic gait has been shown to be particularly energy-intensive. While energy expenditure has been the focus of many studies in adult amputees, this area of research is less developed for paediatric…
- Trial name
- MAPEDE (NCT07076602)
- Testing
- Gait and energy expenditure
- Where
- 8 sites in France
- Volunteers
- 48 people
- Sponsor
- Rennes University Hospital
Amputation, Gait Disorders, Neurologic
Usability of the Smart Hallway System in Clinical Setting
The aim of the study is to examine suitability of data and processed reports acquired from the Smart Hallway system for clinical settings in terms of user acceptability and accuracy for use in clinical practice.
- Trial name
- SmartHallway (NCT06645054)
- Testing
- Standard rehabilitation, Lower-limb prosthesis, Lower-limb orthosis
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Amputation
Prosthetic Socket Fit Testing System
Ensuring a well fitting prosthetic socket is a major challenge in the care of people with amputation. Poor fit causes pain, skin issues, reduced mobility, and lower satisfaction, affecting daily activity and quality of life.
- Trial name
- NCT07491614
- Testing
- Prosthetic socket fit testing system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Washington
Fall Prevention, Balance, Falls
Evaluating Methods to Replicate Stumbles and Slips During Walking
This protocol outlines a study designed to investigate three different methodologies for inducing gait perturbations. Subjects will be divided into two groups: prosthetic users and able-bodied individuals.
- Conditions
- Fall Prevention, Balance, Falls, Amputation of Lower Limb
- Trial name
- NCT07175714
- Testing
- Methodologies to induce gait perturbations
- Where
- 2 sites in Iceland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Össur Iceland ehf
Amputation, Lower Limb
Reliability and Validity of Continuous Inter-limb Stability
To date, there is no valid and reliable measure of continuous inter-limb stability available to healthcare teams treating people with lower limb loss.
- Trial name
- CS (NCT06987019)
- Testing
- 3D motion capture, wearable devices, and functional outcome measures
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Transtibial Amputation, Lower Limb Amputation Below Knee
Clinical Evaluation of the Access Socket Flexible Socket for Transtibial Prosthesis
Transtibial amputation significantly impacts patient autonomy and quality of life, primarily due to the limitations of conventional rigid sockets, which restrict comfort and joint range of motion.
- Trial name
- AS-TT (NCT07592325)
- Testing
- Access Socket (AS), Rigid Socket (RS)
- Where
- 5 sites in France
- Volunteers
- 25 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est