Clinical trials: Lower Extremity Fracture, active
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Fracture of Tibia
Conservative Versus Intramedullary Nailing for Pediatric Tibial Shaft Fractures
Tibial shaft fracture is a common fracture in the pediatric and adolescent population. The outcomes of both conservative and operative treatment are not clear and to date there is no randomized prospective trial comparing…
- Trial name
- CINPED (NCT05501496)
- Testing
- intramedullary nailing, casting
- Where
- 2 sites in Finland
- Volunteers
- 66 people
- Sponsor
- Turku University Hospital
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will be enrolled prospectively in this registry.
- Trial name
- FROST (NCT03598530)
- Testing
- Surgery
- Where
- 15 sites in United States, Belgium and 7 more
- Volunteers
- 1,000 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Hip Fracture, Hip Fracture Surgeries
External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture
This study aims to externally validate ten existing prediction models with a low risk of bias for 30-day mortality following hip fracture.
- Trial name
- PROTECT (NCT06961253)
- Where
- Netherlands
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- JointResearch
Hip Fractures
Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life
Hip fractures often lead to functional limitations, loss of independence, weight loss and decreased well-being. Only half of the patients regain their functional level and 24% die within the following year.
- Trial name
- ProBUS (NCT07036341)
- Testing
- Protein-enriched diet, Progressive resistance exercise
- Where
- 2 sites in Netherlands
- Volunteers
- 102 people
- Sponsor
- Wageningen University
Fracture Femur, Fracture Tibia
Oral Supplementation With a Formulation Based on Cetylated Fatty Acids for Post-fracture Long Bone Healing
This clinical study aims to evaluate the potential benefits of a formulation based on Cetylated Fatty Acids in improving fracture healing of long bones in the lower limbs.
- Trial name
- CETIULTRA-BONE (NCT07299851)
- Testing
- CFA-based food supplement
- Where
- 6 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Pharmanutra S.p.a.
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Ankle Fractures
Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture
The goal of this clinical trial is to compare two different standardized physical therapy rehabilitation programs on outcomes after an ankle fracture.
- Trial name
- AMP (NCT07173088)
- Testing
- Ankle Muscle Power (AMP) program, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brian W. Noehren
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Fracture of Neck of Femur
Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures
The goal of this clinical trial is to verify the safety and effectiveness of orthopaedic surgical navigation system in the treatment of fresh femoral neck fractures.
- Trial name
- NCT06713018
- Testing
- Three cannulated compression screws by navigation system, Traditional three cannulated compression screws
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Distal Femur Fracture
Dual Implant Versus Single Implant Distal End of Femur
The investigators overall study objective is to determine the difference in outcomes for patients over 60 years of age with a displaced distal femur fracture treated with dual distal femur implants (dual plate or IMN/plate) vs.
- Trial name
- NCT05292313
- Testing
- Single distal femur implant, Dual distal femur implants
- Where
- 5 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Dementia, Hip Fracture
Communication for Early Mobilisation of People Living With Dementia Following Surgery for Hip Fracture
This goal of this study is to identify ways that healthcare professionals communicate that are effective in helping a person living with dementia to stand or walk after surgery for a broken hip (hip fracture).
- Conditions
- Dementia, Hip Fracture, Early Mobilisation, Communication Research
- Trial name
- VOICE-HF (NCT07418268)
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
Sarcopenia in Elderly, Sarcopenic Obesity
Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort
Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study Introduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle…
- Conditions
- Sarcopenia in Elderly, Sarcopenic Obesity, Frailty, Femoral Fractures
- Trial name
- NCT06705166
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Pseudarthrosis, Ununited Fracture
Tuebingen Register of Union Failure After Fractures of the Upper and Lower Extremities
TRUFFLE is a register of clinical patient data of failed bone healing and bone non-union after fracture. All patients suffering from a long bone delayed or non-union after fracture and undergoing revision surgery are registered…
- Trial name
- TRUFFLE (NCT06098157)
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Femur Fracture
Dual Implant Versus Single Implant Distal End of Femur
This research study is being conducted to examine the effect of two versus one fixation device for fixation of distal femur fractures.
- Trial name
- NCT06032299
- Testing
- Single Distal Femur Implant, Dual Distal Femur Implant
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Orthopaedic Disorders, Neck of Femur Fracture
Effects of Individualized Physical Therapy and Group Physical Therapy on Functional Outcomes in Patients With Femoral Neck Fracture in Gaza Strip
The research explores how individualized, one-on-one physical therapy programs versus group-based therapy sessions influence recovery in terms of functional mobility, pain reduction, muscle strength, balance, and overall quality…
- Trial name
- neck of femure (NCT07168070)
- Testing
- physical therapy and exercise, group physical therapy vs individualized physical therapy, Group Physical therapy
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University - Gaza
Hip Fracture
Population-based Registry Study on Primary Hip Fracture Surgery
This study aims to describe primary hip fracture surgeries and to identify patient-related and perioperative risk factors affecting outcomes.
- Trial name
- NCT06773884
- Testing
- "Observational Analysis of Primary Hip Fracture Surgery Outcomes"
- Where
- Sweden
- Volunteers
- 90,000 people
- Sponsor
- Region Örebro County
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
The goal of this clinical trial is to learn whether suzetrigine (Journavx®), when added to standard multimodal pain management, can reduce opioid use while providing adequate pain control in adults undergoing surgery for an acute…
- Trial name
- STRIDE-HIP (NCT07905404)
- Testing
- Suzetrigine (Journavx)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Beth Israel Deaconess Medical Center