Clinical trials: Lower Extremity Fractures, open to volunteers
Myocardial Injury
Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study
1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway. 2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow. 3.
- Trial name
- Sipwlefsmdfs (NCT06808841)
- Testing
- Sufentanil injection
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Femoral Neck Fractures
This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of…
- Trial name
- NCT05023369
- Testing
- Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Fracture Healing, Treatment Duration
Smart Crutch Tips for Guided Weight-Bearing in Patients Recovering From Extra-Articular Distal Tibia Fractures
The goal of this clinical trial is to learn whether personalized weight-bearing prescriptions using Smart Crutch Tips™ can improve recovery after surgery for extra-articular distal tibia fractures.
- Conditions
- Fracture Healing, Treatment Duration, Distal Tibia Fracture
- Trial name
- NCT07138066
- Testing
- Smart Crutch Tips™, Finite Element Analysis (FEA), Iterative walking
- Where
- 18 sites in Ukraine
- Volunteers
- 30 people
- Sponsor
- Comeback Mobility Inc
Hip Arthroplasty, Hip Fracture Surgeries
Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia
Sacral erector spinae plane block(S-ESPB) has been recently described. Case reports are showing that it is useful in various types of surgery.
- Conditions
- Hip Arthroplasty, Hip Fracture Surgeries, Femoral Neck Fractures, Postoperative Pain
- Trial name
- NCT07442721
- Testing
- Sacral erector spinae plane block, PENG block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital
EOS
Study of Residuals Deformities After Diaphyseal Femoral Fracture in Children Treated by Skin Traction
Diaphyseal femoral fracture in children <6 years old are treated by the skin traction technique. As demonstrated by numerous studies, given the significant potential for bone remodeling in young children, remodeling (excluding…
- Trial name
- FRAFEMKID (NCT06245993)
- Testing
- EOS imaging
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Femoral Neck Fractures, Internal Fixation
Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation
This study is a prospective randomized controlled clinical study. Patients with femoral neck fracture (AO classification 31-B) will be randomly divided into three-screw fixation group and four-screw fixation group.
- Trial name
- NCT04869332
- Testing
- three cancellous screws, four cancellous screws
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Tibial Fractures
Prosthesis Versus Osteosynthesis in Proximal Tibia Fractures
The aim of this study is to compare knee function and pain one year after treatment of intra-articular proximal tibia fracture using either osteosynthesis with a locking plate (ORIF) or primary total knee replacement (TKR) in…
- Trial name
- POSITIF (NCT03172715)
- Testing
- Locking plate, TKR
- Where
- 8 sites in Finland
- Volunteers
- 98 people
- Sponsor
- Central Finland Hospital District
Tibial Fractures, Lower Extremity Fracture
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
This study will look at the effect of using a blood flow restriction device during low load strengthening exercises on patients with tibial shaft fractures, compared to patients performing exercise without the device.
- Trial name
- NCT06496035
- Testing
- Blood Flow Restriction with low load exercise, Therapeutic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Tibia Fracture, Humerus Fracture
A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects
This project consists of a prospective case design. Study candidates will include all patients ages 18 and over who were evaluated at UCSD and found to have a critical-sized humerus, femur, or tibia segmental defect that would be…
- Conditions
- Tibia Fracture, Humerus Fracture, Femoral Fracture, Long Bone Segmental Defect
- Trial name
- NCT05668182
- Testing
- TRUMATCH Graft Cage
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Diego
Fracture, Lengthening; Leg
Pediatric Orthopaedic Implant Safety & Efficacy
Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.
- Conditions
- Fracture, Lengthening; Leg, Orthopedic Disorder, Deformity of Limb
- Trial name
- Global POISE (NCT05361980)
- Testing
- Pediatric orthopaedic implant
- Where
- Canada
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia