Clinical trials: Lower Extremity Fractures
Hip Fracture, Stroke
Implementation of the MOX Activity Monitor in Hospitalized Geriatric Rehabilitation
Staying active is essential for healthy aging, but hospitalized older adults in rehabilitation often move very little. This study explores how much physical activity these patients actually get and how it relates to their…
- Conditions
- Hip Fracture, Stroke, Fraility
- Trial name
- NCT07124247
- Testing
- Activity registration for one week with an activity monitor (MOX1)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Cancellous Bone Autograft, Bone Substitute
Cancellous Bone Autograft, Bone Substitute, Local Antibiotic, and Fresh Blood for Ununited Fixed Femoral and Tibial Fractures
This study aimed to assess the clinical and radiological outcomes of the usage of autogenous bone graft mixed with bone substitute, fresh blood of patient and local antibiotic used as an onlay graft in treatment of nonunion or…
- Conditions
- Cancellous Bone Autograft, Bone Substitute, Local Antibiotic, Fresh Blood
- Trial name
- NCT07561788
- Testing
- Revision using a composite graft
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Tanta University
Femoral Neck Fractures
Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
RATIONALE: Collecting and storing bone samples from patients with osteoporotic and nonosteoporotic fracture to study a special vessel subtype in the laboratory may help surgeon learn more about the relationship between bone…
- Trial name
- NCT02750046
- Testing
- total hip arthroplasty or proximal femoral nails
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Ankle Fractures, Osteoarthritis, Ankle
Stability of Distal Tibiofibular Syndesmosis With or Without Fixation of Posterior Fragments in Bimalleolar Fractures
Background and Rationale: Injury to the tibiofibular syndesmosis in ankle fractures is a major prognostic factor for the development of post-traumatic osteoarthritis.
- Trial name
- SYNDESMOSE (NCT07755462)
- Testing
- Surgical management of bimalleolar ankle fractures with osteosynthesis of the posterior fragments., Surgical management of bimalleolar ankle fractures without osteosynthesis of the posterior fragments
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Hip Fractures, Surgical Blood Loss
Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures
The objective of this study is to evaluate the effect of Tranexamic Acid (TXA) on blood loss and need for perioperative blood transfusion following intertrochanteric and subtrochanteric femur fractures.
- Trial name
- NCT02580227
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Hip Fracture
Comparative Study of Analgesic Effect of Ultrasound Guided PENG Block vs FEMORAL BLOCK in Hip Fracture
To study the analgesic effect of ultrasound guided PENG Block vs Femoral nerve block in patients with Hip fracture presenting to Emergency department
- Trial name
- NCT06311630
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Femoral Fractures
Standard Reaming Versus Reaming/Irrigating/Aspirating for Intramedullary Nailing of Femoral Shaft Fractures
Reaming (enlarging of the bone canal) is commonly performed prior to the insertion of intramedullary nails for the fixation of long bone fractures.
- Trial name
- STAFF (NCT00534326)
- Testing
- Standard Reaming, Reaming/Irrigating/Aspirating
- Where
- 9 sites in United States
- Volunteers
- 158 people
- Sponsor
- Prisma Health-Upstate
Fracture of Humerus, Fracture of Ulna Radius
3D Geplante Osteosynthesen Mit Patientenspezifischen Zielvorrichtungen
Goal of this study is to evaluate the accuracy of 3D computer-planned fracture fixation with patient-specific instruments for clavicle, upper extremity, lower extremity and pelvis fractures compared with the standard procedure of…
- Conditions
- Fracture of Humerus, Fracture of Ulna Radius, Fracture of Clavicle, Fracture of Hand
- Trial name
- NCT02826538
- Testing
- fracture fixation with patient specific guides, standard procedure of fracture fixation
- Where
- 2 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- Balgrist University Hospital
Sarcopenia, Hip Fractures
Effects of Fish or Meat Consumption in Elderly
Health effects of fish consumption have been demonstrated in epidemiological studies and in controlled intervention studies in a number of different population groups, however, randomized controlled studies on the effect of fish…
- Trial name
- NCT02045355
- Testing
- Fish intervention
- Where
- 2 sites in Norway
- Volunteers
- 14 people
- Sponsor
- University of Bergen
Wound Infection, Fractures, Open
Tobramycin Injection to Prevent Infection in Open Fractures
The goal of open extremity fracture (OEF) treatment is to promote fracture healing and restore function while preventing the development of infection.
- Conditions
- Wound Infection, Fractures, Open, Surgical Site Infection
- Trial name
- NCT04964947
- Testing
- Tobramycin Injection
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Massachusetts General Hospital
Proximal Femur Fracture
Femur Transtrochanteric Fractures Treated With Dynamic Hip Screw and Calcium Sulfate Scaffold.
This is a randomised prospective comparison study to evaluate the incidence of cut - out failure of the dynamic hip screw implant alone compared to the dynamic hip screw adding calcium sulfate through the cervical canal before…
- Trial name
- geneX (NCT05091359)
- Testing
- Study group with absorbable graft of tricalcium ß phosphate / calcium sulfate hemihydrate paste
- Volunteers
- 36 people
- Sponsor
- Hospital Regional Tlalnepantla
Postoperative Cognitive Dysfunction, Orthopedic Procedures
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia.
- Conditions
- Postoperative Cognitive Dysfunction, Orthopedic Procedures, Postoperative Pain Management, Hip Fracture
- Trial name
- REMIND-ORTHO (NCT07113483)
- Testing
- Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Analgesia After Fracture Femur Surgeries
Comparing Erector Spinae and Fascia Iliaca Blocks for Pain Relief After Femur Surgery.
This clinical study compares two types of nerve blocks used to control pain in adult patients undergoing surgery on the upper (proximal) or middle (midshaft) part of the femur (thigh bone).
- Trial name
- NCT06990958
- Testing
- Erector Spinae Plane Block (ESPB) group, Fascia iliaca compartment block (FICB)
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University
Pain, Postoperative
The Effect of Femoral Nerve Block on Opioid Requirements After Surgery for a Femur Fracture in Children
This study evaluates the effect of a femoral nerve block on opioid requirements following femoral fracture fixation with flexible nails in the paediatric population. This is a double blind, prospective randomized clinical trial.
- Trial name
- NCT00175591
- Testing
- Administration of a femoral nerve block (bupivacaine HCL)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Lateral Malleolus Fractures
Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
The aim of this prospective clinical trial study is to evaluate the clinical and radiological outcomes of treating non-union of the lateral malleolar ankle fractures by double compression screw fixation technique.
- Trial name
- NCT07539922
- Testing
- Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Hip Fracture (First Incidence of)
Diet and Hip Fracture Risk in the United Kingdom Women's Cohort
Hip fracture is a common serious injury in older women that reduces quality of life and can lead to premature death. In the United Kingdom, hip fractures are estimated to account for 1.5 million hospital bed days used per year…
- Trial name
- NCT05081466
- Testing
- Dietary pattern, Fruit and vegetable intake, Meat intake
- Where
- United Kingdom
- Volunteers
- 35,372 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Proximal Femur Fracture
Evaluation of the Proximal Femoral Nail Antirotation With Cement Augmentation in Osteoporotic Femoral Neck Fractures
This is an open multicenter study, evaluating a new operative technique in femur neck fractures. The treatment consist of augmentated nails in cases of subtrochanteric or inter fracture due to osteoporosis.There two routine…
- Trial name
- NCT01235169
- Testing
- Proximal Femoral Nail Antirotation(PFNA) with cement augmentation
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Hip Fracture
Hip Protector for Prevention of Hip Fracture
This study aims to evaluate the efficacy of the investigators PSU hip protector for prevention of fracture in elderly.The eligible patients include those with previous diagnosed as unilateral hip fracture.
- Trial name
- NCT01017341
- Testing
- PSU hip protector
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Prince of Songkla University
Hip Fractures, Analgesia
Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
It is well-established that hip fractures impose a significant medical, socioeconomic, and financial burden. In the elderly population, the associated mortality and morbidity are particularly pronounced: within one year following…
- Conditions
- Hip Fractures, Analgesia, Femoral Nerve
- Trial name
- NCT06862154
- Testing
- IV Analgesia- Fentanyl, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
Hip Fractures
Early Femoral Block in Elderly With Hip Fracture
Assess if the addition of an early femoral nerve block (performed within 2 hours from the admission in emergency department through a femoral nerve catheter) in the elderly patients (> 70 years) with hip fracture, reduces the…
- Trial name
- NCT03092466
- Testing
- femoral nerve catheter, femoral group, control group
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- ASST Gaetano Pini-CTO