Clinical trials: Lower Extremity Function
Chronic Low-back Pain
Comparing the Effect of Chiropractic Manipulation and Spinal Decompression Device Treatment
This study is aimed to compare the effects of chiropractic spinal manipulative therapy and spinal decompression device treatment on lower extremity muscle strength, balance performance, lumbar range of motion and mobility…
- Trial name
- NCT05460286
- Testing
- Chiropractic Manipulation, Spinal Decompression Device Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mustafa AĞRAŞ
Knee Osteoarthritis
Mixed Methods Assessment of Exercises for Knee OA
Osteoarthritis (OA) is a condition that causes cartilage loss, bony remodeling, joint stiffness and generalized muscle weakness. 90% of OA presentation has been reported within the leg; with 44% affecting the knee joint.
- Trial name
- NCT02734342
- Testing
- exercise
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Salford
Ankle Sprains
Ankle Taping and Functional Ankle Instability
Background and purpose: Ankle inversion sprains are the commonest injuries of the lower extremities. Taping is routinely used after ankle sprain to support the joint and prevent reinjury.
- Trial name
- NCT03626051
- Testing
- Rigid tape, Fibular tape
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Endovascular Repair of Aortic Aneurysm, Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities
Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.
Endovascular repair of aortic aneurysm and endovascular treatment of arteriosclerosis obliterans of lower extremities are two kinds of common surgeries in the investigators' hospital.
- Trial name
- NCT02107170
- Testing
- Sevoflurane, Propofol, Remifentanil
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Tao Zhang
ACL Tear, ACL - Anterior Cruciate Ligament Deficiency
Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction
This prospectively study aims to evaluate the evolution of knee joint proprioception on isokinetic dynamometer before and after Anterior Cruciate Ligament (ACL) reconstruction and its relationships with muscle strength, self…
- Trial name
- PRO-ACL (NCT04058574)
- Testing
- Proprioception measurement on isokinetic dynamometer
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Lymphatic Function
Lymphatic Occlusion Pressure in Lower Limb
The lymphatic system is one of the keystones of fluid homeostasis in the interstitium. In analogy with the arterial systolic pressure, the lymphatic pressure can give us information about the functioning of the cardiovascular…
- Trial name
- NCT02405559
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Neuromuscular Diseases
Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function
The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different…
- Trial name
- NCT06439823
- Testing
- ActiMyo®/Syde®
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laurent Servais
Adolescent Idiopathic Scoliosis (AIS)
Effect of Scoliosis and Progressive Resistance Exercises on Clinical and Pulmonary Parameters in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that may affect physical function and pulmonary capacity during adolescence.
- Trial name
- SPRE-AIS (NCT07481279)
- Testing
- Scoliosis Exercises, Progressive Resistance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Parkinson Disease
Effect of a Boxing Program on People With Parkinson Disease
This study is investigating the impact of a boxing training program on people with Parkinson Disease. The investigators were provided data for the intervention group retrospectively by the organizers of the boxing club to assess…
- Trial name
- NCT04781842
- Testing
- Boxing exercise program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Husson University
Ankle Fractures
The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture
Ankle fracture is one of most common bone fracture in Taiwan, although ankle fracture can be treated by surgical operation, local edema, pain and wound poor healing always is noted, according to the investigator's knowledge, no…
- Trial name
- NCT03805347
- Testing
- Helminthostachys zeylanica(L.)Hook, Starch
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Changhua Christian Hospital
Tibial Fractures, Lower Extremity Fracture
Blood Flow Restriction Training in Patients With Lower Extremity Fractures
This study will look at the effect of using a blood flow restriction device during low load strengthening exercises on patients with tibial shaft fractures, compared to patients performing exercise without the device.
- Trial name
- NCT06496035
- Testing
- Blood Flow Restriction with low load exercise, Therapeutic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Sports Physical Therapy
Bowens Technique Versus Mulligan Bent Leg Raise Technique in Kabaddi Players
The purpose of this study is to look into how Mulligan's bent leg raise technique and Bowen's technique affect the functional abilities and range of motion of hamstring-tight Kabaddi players.
- Trial name
- NCT06686225
- Testing
- Bowen's technique., Mulligan bent leg raise technique
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Restless Legs Syndrome, Sleep Quality
Restless Legs Syndrome and Sleep Quality in Pes Planus
Pes planus, also known as flatfoot, is a common foot deformity that can affect the biomechanics of the lower limbs. However, its relationship with neurological conditions has not been studied extensively.
- Conditions
- Restless Legs Syndrome, Sleep Quality, Pain, Quality of Life
- Trial name
- FLAT-RLS (NCT07117591)
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bozok University
Vascular Diseases, Peripheral Artery Disease
The ALOFT Pilot Trial
The ALOFT Pilot Trial will evaluate three pragmatic elements (recruitment, adherence, and follow-up) of neuraxial versus general anesthesia for lower limb revascularization surgery that are necessary to support a successful…
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Surgery
- Trial name
- NCT06067789
- Testing
- neuraxial anesthesia
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Ottawa Hospital Research Institute
High-risk Pregnancy
Leg Heating in Pregnant Women With Obesity
Obesity is a major risk factor for hypertensive disorders of pregnancy (HDP). The underlying mechanisms are largely unclear, but maternal vascular endothelial dysfunction is likely involved.
- Trial name
- NCT06932250
- Testing
- Leg heating
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Amputation
Enhancing Motor Function in Individuals with Lower Limb Amputation
The overall goal of this research project is to investigate the effectiveness and the science of peer-based prosthetic skill training in individuals with leg amputation.
- Trial name
- NCT06638723
- Testing
- Balance and fall recovery training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nevada, Las Vegas
Knee Osteoarthritis
Comparison of Functional Outcomes of Three Surgical Approaches in Knee Arthroplasty
A functional outcomes comparison study of three surgical techniques using minimally invasive surgery mini-incision (MIS) for total knee arthroplasty (TKA), standard para-patellar TKA and the unicompartmental knee arthroplasty…
- Trial name
- NCT00983762
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Peripheral Artery Disease
Leg Heat Therapy in Peripheral Artery Disease
The goal of this randomized, double-blind, sham-controlled clinical trial is to evaluate the benefits of home-based, leg heat therapy (HT) on lower-extremity functioning and quality of life in patients who suffer from…
- Trial name
- NCT05465070
- Testing
- Leg heat therapy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
Anterior Cruciate Ligament Injuries
Can Sensorimotor Function Predict Graft Rupture After ACL Reconstruction
In this longitudinal prospective cohort study including young people with anterior cruciate ligament (ACL) reconstruction, the investigators will evaluate if poor sensorimotor function at baseline can predict 1) graft rupture 2)…
- Trial name
- NCT04162613
- Testing
- Different measures of muscle function such as muscle strength, hop tests, postural orientation and muscle activation
- Where
- Sweden
- Volunteers
- 201 people
- Sponsor
- Umeå University
Stroke
Efficacy of Bilateral Stimulation With Task-oriented Training in Improving Lower Limb Motor Functions in Patients With Stroke
This proposed study aims to compare the effects of unilateral and bilateral transcutaneous electrical nerve stimulation (TENS). It will compare the effectiveness of bilateral TENS + task-oriented training (TOT) with unilateral…
- Trial name
- RCT (NCT02152813)
- Testing
- TENS and Task-orientated training
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University