Clinical trials: Lower Extremity Function
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Elders
Turkish Version of Lower Extremity Functional Scale in Elders
This study was conducted in order to analyze the validity and reliability, and psychometric properties of the Turkish version of the Lower Extremity Functional Scale (LEFS-T) in elder adults.
- Trial name
- NCT05035329
- Testing
- Outcome measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Hip Fracture, Postoperative Recovery
Total Intravenous Versus Inhalational Anesthesia in Patients Undergoing Hip Fracture Surgery
This prospective observational study aims to compare total intravenous anesthesia (TIVA) with sevoflurane-based inhalational anesthesia in patients aged 65 years and older undergoing hip fracture surgery under general anesthesia.
- Trial name
- NCT07860996
- Testing
- Propofol-based Total Intravenous Anesthesia, Sevoflurane-based Inhalational Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Spinal Cord Injuries
Functional Electrical Stimulation During Cycling in People With Spinal Cord Injury
Neuroscience research that has identified potential for recovery (neuroplasticity) following incomplete SCI has changed clinical practice away from compensation strategies towards optimizing recovery.
- Trial name
- iCycle (NCT03834324)
- Testing
- FES
- Volunteers
- 11 people
- Sponsor
- University of Southampton
Stroke
A Study on the Effectiveness Evaluation in Stroke Patients Using Lower Limb Assistive Walking Devices
The main purpose of this clinical trial is to evaluate the effectiveness and safety of the MI-R1 walking machine in lower limb motor function training for stroke patients. The main question is to answer: 1.
- Trial name
- NCT06564480
- Testing
- MI-R1 lower limb walking machine assisted training device, Walking rehabilitation training under the guidance of therapists
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Lower Leg Amputations
Prosthetic Use, Mobility and Daily Functioning
The goal of the project is to explore which elements of rehabilitation that influence mobility in new and experienced unilateral lower-limb amputees.
- Trial name
- ProMob (NCT04904003)
- Testing
- Rehabilitation Intervention
- Where
- 2 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Oslo Metropolitan University
Overactive Bladder Syndrome, Multiple Sclerosis
Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Patients With Multiple Sclerosis
The aim of the study (OVERACT_V1) is to verify if the isometric contraction of ankle plantarflexor and Hamstring muscles, induces a significant reduction of overactive bladder symptoms in patients with Multiple sclerosis.
- Conditions
- Overactive Bladder Syndrome, Multiple Sclerosis, Muscle Strain
- Trial name
- NCT03322748
- Testing
- Usual physical therapy+ strengthening of lower limbs muscles, Usual physical therapy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele
Pes Planus Down Syndrome Patients
Down Syndrome and Effects of Foot Muscle Exercise
Down syndrome (DS) is a common chromosomal pediatric disorder and accounts for approximately 8 % of all congenital anomalies. Children with DS experience delays in Cognitive, Physical, Speech and Language development.
- Trial name
- NCT05251935
- Testing
- Foot Muscle Exercise Protocol, Arch Support Insole and One Leg Balance Activities
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- Ziauddin University
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
Patellofemoral Pain Syndrome
Kinematics of Lower Limb, Pain and Function of the Women With Patellofemoral Pain Syndrome
Assess pain, function, trunk and lower limbs kinematic during functional tasks after hip muscle strengthening versus hip muscle strengthening and sensory motor training in lower limbs.
- Trial name
- NCT01804608
- Testing
- Strength, Sensorimotor
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Nove de Julho
Mobility Limitation
Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance
In this study, we will randomly assign 360 older adults to 12 months of 5 minutes per day of functional resistance training or to a delayed treatment control condition, and measure the impact of the training on measures of lower…
- Trial name
- FASTNIA (NCT06396247)
- Testing
- Functional Activity Strength Training
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Milton S. Hershey Medical Center
Hamstring Tightness, Hamstring Injury Prevention
Effects of Neurodynamic Sliding Versus Eccentric Training on Lower Extremity Function, Strength and Proprioception in Athletes with Short Hamstring Syndrome.
Hamstring strains are among the most common injuries in field sports, accounting for 10% of all team sports injuries and often leading to long-term absence from activities.
- Trial name
- NCT06748560
- Testing
- Neurodynamics, Eccentric training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Yeditepe University
Physical Fatigue, Return to Sport
The Effect of Physical Fatigue on Lower Limb Functional Performance Tests in a Healthy Population
The main objective of this project is: 1. To assess the influence of physical fatigue on a return-to-play test battery in a healthy population. In a later stage, these experiments could be carried out in a clinical context (e.g.
- Conditions
- Physical Fatigue, Return to Sport, Injury Prevention, Functional Performance
- Trial name
- NCT04029935
- Testing
- Physical Fatigue, Control
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Varicose Veins of Lower Limb, Varicose Veins
Compression And Functional Ability After Endovenous Varicose Vein Treatment
Study's aim is to study possible differences in post-operative rehabilitation, functional ability and visual disturbances after endovascular varicose intervention (RF-catheter and foam sclerotherapy) in two study groups, where…
- Trial name
- NCT03613376
- Testing
- Class II compression stockings
- Where
- Finland
- Volunteers
- 109 people
- Sponsor
- Oulu University Hospital
Soft Tissue Sarcoma, Bone Sarcoma
Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Primary bone and soft tissue sarcomas are an exceptionally rare form of cancer, collectively accounting for only 1% of all malignancies diagnosed.
- Trial name
- QOLSarcoma (NCT05051059)
- Testing
- Functional outcome, Health related quality of life (HRQoL) assessment
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy
Does Passive Spinal Mobilization Improve Lower Limbs Strength and Function
Previous studies have shown that peripheral muscles weakness or inhibition is related to spinal disorders. Passive mobilization and manipulation are likely to reverse such muscle weakness.
- Trial name
- NCT02523508
- Testing
- Experimental group, Control group
- Where
- Hong Kong
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hip Fracture, Post Surgery Recovery, Muscle Resilience
Hip Fracture and Muscle Resilience
The aging of the population is a major public health problem, particularly with regard to the quality of life and the maintenance of autonomy.
- Trial name
- HIPRESM (NCT04167020)
- Testing
- High definition surface electromyography (HD-sEMG)
- Where
- 4 sites in France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Accidental Falls
Training Improves Balance Control
The purpose of this study was to evaluate the effect of a group-based functional and specific balance training program on balance function in healthy older adults.
- Trial name
- NCT01547988
- Testing
- Balance Training Intervention
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stroke
Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke Patients
RATIONALE: The previous study resulted that the gait training using Functional Electrical Stimulation (FES) improved the ankle joint function and the walking ability for the chronic stroke patients with foot drop.
- Trial name
- PLEASURE (NCT02897752)
- Testing
- gait training with WA, usual gait training
- Where
- 24 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa