Clinical trials: Lower Extremity Function
Stroke, Walking Impairment
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Current evidence and clinical applications of robotic gait training devices for motor function recovery post-stroke are increasingly available.
- Trial name
- NCT07057700
- Testing
- welwalk training, physical therapy
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Ruijin Hospital
Sarcopenia
Lower-Limb Rehabilitation Robot Training for Sarcopenia
The goal of this clinical trial is to learn whether lower-limb rehabilitation robot training combined with nutrition education can improve muscle mass and physical function in adults aged 60 years or older with sarcopenia.
- Trial name
- NCT07830472
- Testing
- Lower-Limb Rehabilitation Robot Training, Nutrition Education, Usual Care Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University Hospital
Hallux Limitus, Ankle Joint
Teenage Functional Hallux Limitus and Ankle Dorsiflexion Study
This study aims to identify a possible correlation between reduced mobility of the first toe under load and reduced mobility of the ankle ROM in healthy adolescent basketball players.
- Trial name
- NCT05399472
- Testing
- Dorsiflexion lunge test, Jack Test
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Bologna
Primary Lymphedema, Aerobic Exercise
The Effects of Aerobic Exercise in Patients With Primary Lower Extremity Lymphedema
Our aim in this study is to evaluate the effects of lymphedema on exercise capacity, body composition, functional level and quality of life in lymphedema patients with primary lower extremity involvement.
- Trial name
- NCT06327412
- Testing
- Aerobic exercise on the treadmill, Walking between 12-13 RPE (The Borg Rating of Perceived Exertion) according to the Modified Borg Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kayseri City Hospital
Osteoarthritis, Avascular Necrosis
Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and clinical outcome data on the Hyperion® system in primary and…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Functional Deformities
- Trial name
- NCT03382665
- Where
- 3 sites in Germany
- Volunteers
- 70 people
- Sponsor
- Zimmer Biomet
Cerebral Palsy
Functional Effects and Impact on Motor Neuronal Activity of Early and Intensive Motrice (Hand and Arm Bimanual Intensive Therapy Including Lower Extremities: HABIT-ILE) Reeducation in Children With Pre-school Bilateral Cerebral Palsy
One of the urgent priorities in the field of pediatric neuro-rehabilitation is the development of efficient early motor interventions for children with cerebral palsy (CP).
- Trial name
- MOOV (NCT04362800)
- Testing
- MRI, Electro-Encephalography-High Density, 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
Cerebral Palsy (CP)
Effect of Robotic Gait on Functions in Cerebral Palsy
Cerebral palsy (CP) is a condition characterized by various motor disorders and limitations caused by brain damage. Neurodevelopmental treatment (NDT) is one of the primary approaches in the rehabilitation of individuals with CP.
- Trial name
- NCT07566767
- Testing
- Neurodevelopmental Treatment (NDT), Robotic Gait Trainer
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Medipol University
Ankle Sprain, Ankle Injuries
Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability
The overall aim of this project is to determine the effect of a tibiofibular joint manipulation on the neuromuscular response of the fibularis longus and soleus muscles in individuals with chronic ankle instability.
- Conditions
- Ankle Sprain, Ankle Injuries, Sprain
- Trial name
- NCT00601471
- Testing
- proximal tibiofibular manipulation, distal tibiofibular manipulation, no intervention
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Virginia
Football Players
Efficacy of Plyometric Training Isometric Strength Training on Quadriceps Strength and Functional Performance.
This study aims to investigate the influence of an eight-week plyometric and quadriceps strength training program on muscular strength, sprint, and functional performance in collegiate football players.
- Trial name
- Isometric (NCT05056792)
- Testing
- Isometric strength training for 8 week, Conventional training
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Elderly
Relationship of Balance, Functional Capacity and Fear of Movement With Lower Extremity Muscle Strength in Elderly
Aging is a period in which the morphological, physiological and pathological changes progress negatively, accompanied by various diseases and regression of physical and mental abilities.
- Trial name
- NCT04347356
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bezmialem Vakif University
Stroke
Transcranial Direct Current Stimulation on the Risk of Falls and Lower Limb Function for Acute Stroke
Transcranial direct current stimulation (tDCS) has shown promising results in the modulation of cortical excitability and the promotion of neuronal plasticity after stroke.
- Trial name
- NCT02422173
- Testing
- Anodal transcranial direct current stimulation, Cathodal transcranial direct current stimulation, Bilateral transcranial direct current stimulation
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Cerebral Palsy
Changes Induced by Early HABIT-ILE in Pre-school Children With Uni- and Bilateral Cerebral Palsy
Studying in two randomized controlled trials (RCT) the changes induced by early HABIT-ILE in functional, neuroplastic and biomechanical assessment in children with unilateral and bilateral CP.
- Trial name
- EarlyHABIT-ILE (NCT04020354)
- Testing
- HABIT-ILE, Usual Care
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Functional Ankle Instability
Effects of Taping on Performance in Adolescent Volleyball Players With Patient-Reported Ankle Instability
The purpose of this study is to investigate the effects of different types of taping application to functional performancein adolescent volleyball players with functional ankle instability.
- Trial name
- NCT07165613
- Testing
- Kinesiotape, Dynamic tape
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Blood Flow Restriction Training on Lower Limb Motor Function in Stroke Patients With Hemiplegia
flow restriction training combined with routine rehabilitation training can promote the recovery of lower limb muscle strength on the hemiplegic side of stroke patients, improve the lower limb motor function of patients, and…
- Trial name
- NCT06461013
- Testing
- Blood flow restriction
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yunhong Tian
Incomplete Spinal Cord Injury
Device-induced Intermittent Hypoxia in Persons With Incomplete Spinal Cord Injury
Spinal cord injury (SCI) is a devastating disability with physical, social and vocational consequences. Owing to its overwhelming complications, the cost of treatment and rehabilitation increases constantly.
- Trial name
- NCT05491837
- Testing
- Device induce acute intermittent hypoxia 9 % of Oxygen, Normoxia 21% of oxygen
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Recurrent Patella Dislocation
MPFL vs Campbell in Recurrent Patella Dislocation
This study will compare anatomic Medial Patellofemoral Reconstruction from Hamstring graft with non anatomic reconstruction according to Campbell.
- Trial name
- NCT05488275
- Testing
- Surgery
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Spinal Cord Injury, Spinal Cord Injury Thoracic
Investigating the Impact of Spinal Cord Electrical Stimulation Combined With Individualized Physical Therapy on Lower Extremity Function in Patients With Spinal Cord Injury
This study aims to understand the differences in the effects of two rehabilitation approaches on lower limb function recovery in patients with spinal cord injuries: 1.
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Thoracic, Spinal Cord Injury/Damage, Spinal Cord Injury T1-L2
- Trial name
- NCT07037628
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Lian-Cing Yan, MSPT
Anterior Cruciate Ligament Injuries
Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks
Anterior cruciate ligament (ACL) injuries are frequent in handball especially among young players. Recent investigations highlighted the implication of the central nervous system as a potential risk factor for ACL rupture.
- Trial name
- NEURIBIO (NCT04736511)
- Testing
- Star Excursion Balance Test, Single leg Drop Vertical Jump, Unplanned sidestep cutting manoeuvre
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anterior Cruciate Ligament Rupture
Return to Work and Functional Results of French Soldiers After Anterior Cruciate Ligament Reconstruction
The return to work in the military population after surgical reconstruction of the anterior cruciate ligament (ACL) has been poorly investigated within the French armed forces.
- Trial name
- NCT04668677
- Testing
- On-line questionnaire
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hemiplegic Cerebral Palsy
Effect of Hand Arm Bimanual Intensive Technique Including Lower Extremity (HABIT-IL) on Hemiplegic Cerebral Palsy
The aim of this study is to determine the functional status of upper extremity using HABIT \& HABIT-ILE. And to compare the effects of HABIT with and without lower extremity technique on functional status of hemiplegic cerebral…
- Trial name
- NCT05358028
- Testing
- Hand Arm Bimanual Intensive Technique including Lower Extremity (HABIT-IL), Hand Arm bimanual intensive Technique (HABIT)
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University