Clinical trials: Lower Extremity Function
Stroke
A Clinical Trial to Study the Effects of Bobath Therapy With and Without EMG Biofeedback Therapy in Stroke Patients
Stroke is a leading cause of disability worldwide. It has a negative impact on the cognitive and sensorimotor functions. Motor recovery becomes essential in rehabilitation phase to make the patient independent in activities of…
- Trial name
- NCT05953272
- Testing
- EMG Biofeedback therapy and Bobath therapy, Bobath therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- National Institute for Locomotor Disabilities (Divyangjan), India
ACL Injury, Meniscus Lesion
Muscle Function and Traumatic Knee Injury in Sports
The aims of the project are to 1) evaluate different aspects of muscle function and its role as a potential risk and/or protective factor for traumatic knee injury in youth female athletes; 2) develop and evaluate a battery of…
- Conditions
- ACL Injury, Meniscus Lesion, Cartilage Injury, Ligament Injury
- Trial name
- NCT03479775
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University
Diabetic Polyneuropathy, Amputation
Comparison of Joint Position Sense in Diabetic and Traumatic Transtibial Amputees
This study evaluated the effect of joint position sense on compliance with the prosthesis, balance and functional performance in individuals with lower extremity amputation due to diabetic polyneuropathy.
- Trial name
- NCT05542901
- Testing
- Joint Position Sense Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Martial Arts, Body Building
Lower Limb Performance, Balance and Coordination Differences Between the Muay Thai Athletes and Recreational Bodybuilders
Purpose: The aim of this study was to compare balance, coordination and lower extremity functional performances of Muay Thai (MT) athletes and bodybuilders (BB).
- Conditions
- Martial Arts, Body Building, Functional Performance
- Trial name
- NCT04563312
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pelvic Fractures, Weight Bearing
Early Partial Weight-bearing May Improve Functional Recovery Without Increasing Complications Despite This Potential, Limited Randomized Studies Have Evaluated Early Weight-bearing After Pelvic Fixation Surgeries
The goal of this randomized clinical trial is to compare between the effect of immediate weight bearing (WB) versus delayed weight bearing in improving function, pain, gait, quality of reduction radiologically, muscle strength…
- Trial name
- NCT07538726
- Testing
- Immediate Partial Weight Bearing
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Neuromuscular Disorders
Bidirectional Tuning of the AFO Stiffness
The goal of this pilot study with a pre-post design is to investigate the effects of separate individualization of the AFO stiffness towards plantar- and dorsiflexion in a spring-hinged AFO on walking compared to a spring-like…
- Trial name
- NEUROSWING (NCT06412055)
- Testing
- NEURO SWING AFO (Fior& Gentz, Lüneburg, Germany), WalkOn Reaction® (Ottobock, Duderstadt), Matrix Max2® (TruLife, Dublin, Ireland)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Obstructive Pulmonary Disease
Electrical Stimulation for Respiratory and Leg Muscles Impact on COPD Patients
Electrical neuromuscular stimulation electrode patches will be applied over the intercostal respiratory muscles and leg muscles In addition to conventional pulmonary rehabilitation
- Trial name
- NCT06670443
- Testing
- experimental group, control group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Effects of Exercise on Older Adults
Effects of Resistance-based Exercise Snacks With Varying Fragmentation Patterns on Lower Limb Function and Executive Cognition in Pre-frail Older Adults
This four-arm randomized pilot trial (N=48-60) compares four fragmentation patterns of a three-exercise resistance snack (sit-to-stand, squat, heel raise; 15 repetitions/exercise/day) in pre-frail older adults (Fried score 1-2…
- Trial name
- NCT07551206
- Testing
- Highly Fragmented Exercise Snack, Moderately Fragmented Exercise Snack, Lowly Fragmented Exercise Snack
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital University of Physical Education and Sports, China
Plyometric Exercise, Sedentary Behavior
Efficiency in 4-week Plyometric Training: Lower Limb Improvement in Sedentary Adults
The goal of this clinical trial is to compare the effects of different volumes of plyometric training on lower limb muscle strength, power, and muscle activity in sedentary individuals.
- Trial name
- NCT05928130
- Testing
- plyometric training protocol
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rodrigo Lizama Perez
Diabetic Foot Ulcer
Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation.
- Trial name
- NCT07109895
- Testing
- Standard Care Only, Custom Insole + Standard Care, TENS + Custom Insole + Standard Care
- Where
- Pakistan
- Volunteers
- 159 people
- Sponsor
- University of Lahore
Leg Injuries, Ankle Injuries
Medico Economic Evaluation of Dermal Substitute Integra® for Coverage of Inferior Limb Traumatic Skin Loss
Comparison of 2 techniques of surgery on patients with inferior limb traumatic wounds: the innovative technique Integra® and the technique of reference: the flap surgery.
- Conditions
- Leg Injuries, Ankle Injuries, Foot Injuries
- Trial name
- INTEGRA® (NCT00906672)
- Testing
- INTEGRA®, Flap technique
- Where
- 7 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Protruded Disk
CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
The purpose of the study is to evaluate the efficacy of CLARIX™ 100 and CLARIX™ CORD 1K as a tissue barrier when used as an annular patch in discectomy patients with low back \& leg pain when compared to traditional discectomy…
- Trial name
- NCT03113786
- Testing
- CLARIX™100, CLARIX CORD 1K
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Amniox Medical, Inc.
Knee Discomfort
Hold-relax and Muscle Energy Techniques in Patients With Post-traumatic Knee Stiffness
The study was conducted to compare the effects of hold-relax and muscle energy technique on pain, range of motion an lower extremity function in patients with post-traumatic knee stiffness.
- Trial name
- NCT07438561
- Testing
- Hold-Relax Technique, Muscle Energy Technique, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Traumatic Brain Injury
The Environment's Impact on Thinking When Added to Leg Cycling in People With TBI: VITAL
Aerobic exercise is a promising treatment modality for cognition in persons with TBI, but effects are consistently small. This study aims to investigate the effect of difference environments during moderate intensity cycling…
- Trial name
- VITAL (NCT04901286)
- Testing
- Exercise Only, Exercise + Non-Immersive Virtual Reality, Exercise + Immersive Virtual Reality
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Ankle and or Hindfoot Injury
The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot
The purpose of this randomized controlled trial is to assess the effect of DN at either the site of the identified myofascial trigger point/s (MTrP) of in the same muscle, but away from the MTrP site/s in individuals with ankle…
- Trial name
- NCT04487327
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Regis University
Hip Fractures, Osteoporosis
Effect of a Multicomponent Intervention on Functional Capacity After Hip Fracture
Due to the clinical, functional, cognitive and social complexity of older adults after fragility hip fractures (defined as those produced by low-impact trauma), the investigators propose an intervention.
- Conditions
- Hip Fractures, Osteoporosis, Fall, Frailty Syndrome
- Trial name
- ActiveFLS (NCT05435534)
- Testing
- ActiveFLS intervention, Usual care group
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Fundacion Miguel Servet
Traumatic Amputation of Lower Extremity
A Comparison of External Mechanical Work Between Different Prosthetic Feet
Recent dysvascular and diabetic amputees as well as older, long-term traumatic amputees are at risk of functional decline, joint degeneration, skin breakdown and further limb loss due to the forces placed on the contralateral…
- Trial name
- SEW (NCT01340807)
- Testing
- Specialized Functional Prosthetic Training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Ankle Sprains
Ankle Taping and Functional Ankle Instability
Background and purpose: Ankle inversion sprains are the commonest injuries of the lower extremities. Taping is routinely used after ankle sprain to support the joint and prevent reinjury.
- Trial name
- NCT03626051
- Testing
- Rigid tape, Fibular tape
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Meniscus Injury, Kinesio Taping
Kinesiotaping in Isolated Meniscus Injuries
The effect of kinesiotaping on pain and functionality in isolated meniscus injuries.
- Trial name
- NCT07574307
- Testing
- Exercise, kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Bandırma Onyedi Eylül University
Stroke, Hemiparesis
Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke
This is a small pilot randomized controlled trial which will enroll both subacute (<6 mos) and chronic (>6 mos) stroke survivors with ankle dorsiflexion weakness.
- Conditions
- Stroke, Hemiparesis, Footdrop
- Trial name
- NCT02199795
- Testing
- Contralaterally Controlled Neuromuscular Electrical Stimulation, Cyclic Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- MetroHealth Medical Center