Clinical trials: Lower Extremity Function
Amputation, Prostheses and Implants
Regenerative Peripheral Nerve Interface for Control of Lower Limb Prostheses
Individuals with an above-knee lower limb amputation are known to walk more slowly, expend more energy, have a greater risk of falling, and have reduced quality of life compared to individuals without amputation and those with…
- Trial name
- NCT06275282
- Testing
- Intramuscular electrodes
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan
Spinal Cord Injuries
Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
Comparison of different types of transcranial magnetic stimulation techniques which are intermittent theta burst stimulation (iTBS) and high frequency repetitive transcranial magnetic stimulation (rTMS) in patients with spinal…
- Trial name
- NCT06248476
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Post Stroke, Lower Limb
Comparative Effects of SBES Versus TOT on Lower Limb Motor Function in Post-Stroke Patients
Stroke-induced lower limb impairments severely inhibit functional independence and mobility in survivors. Inventive techniques like Synergy-Based Electrical Stimulation (SBES) and Task-Oriented Training (TOT) support favorable…
- Trial name
- NCT07718776
- Testing
- synergy Based Electrical stimulation, Task oriented training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Spastic Hemiplegic Cerebral Palsy
Progressive Functional Strength Training in Unilateral Spastic Cerebral Palsy
This study is aimed to investigate effectiveness of progressive functional strength training protocol (functional squat system with virtual reality in leg press, plyometric exercises, exercises with Bosu ball \& heel-rise…
- Trial name
- NCT02460406
- Testing
- traditional physiotherapy, progressive functional strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Hacettepe University
Surgical Treatment
The Evaluation of the Lower Limb Function After Femur Fracture's Operation Treatment
The goal of this study is the evaluation of lower limb function and the quaility of life of the patients after femur fracture operation treatment.
- Trial name
- ELLFF (NCT04062604)
- Testing
- surgery
- Where
- Poland
- Volunteers
- 350 people
- Sponsor
- Jagiellonian University
Functional Deficits, Manipulation
Effects of Mobilization in Conjunction With Therapeutic Exercise in Participants With a History of Ankle Sprain
Our purpose was to examine the combined effects of thrust mobilization of the proximal and distal ankle joints in conjunction with a six-week rehabilitation program on ankle function in subjects reporting chronic ankle…
- Conditions
- Functional Deficits, Manipulation, Rehabilitation
- Trial name
- NCT02945943
- Testing
- High Velocity Low Amplitude mobilization, Exercise Protocol
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Amputation, Amputation; Traumatic, Leg, Lower
Evaluation of Functionality of Amputees According to the Medicare Functional K Classification System
The aim of our study is; To evaluate the functionality of lower extremity unilateral amputees, to ensure that the results of the Medicare Functional K Classification System, which provides subjective data for the evaluator…
- Trial name
- NCT06293443
- Testing
- Lower extremity unilateral amputee
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Medipol University
Spastic Diplegic Cerebral Palsy, Gait, Spastic
Effects of LIFT on Gait and Balance in Spastic Diplegic Cerebral Palsy Children
The goal of this Randomized control trial was to evaluate the outcome of limb intensive functional training (LIFT) on gait and balance in spastic diplegic cerebral palsy children with age 3-7 years.
- Trial name
- NCT07121426
- Testing
- Lower limb Intensive Functional Training, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Tibial Fracture
Criteria-Based Rehabilitation After Tibial Fracture Fixation: A Randomized Controlled Trial
This randomized controlled trial will evaluate the effectiveness of a criteria-based progressive loading and functional rehabilitation program compared with usual physiotherapy in adults following surgical fixation of traumatic…
- Trial name
- NCT07810478
- Testing
- Criteria-Based Progressive Loading and Functional Rehabilitation Program
- Where
- Palestinian Territories
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Unstable Strength Training, Balance Assessment
To Design an Experimental Intervention, 62 Youth Volleyball Players Were Divided Into an Experimental Group and a Control Group and Underwent 10 Weeks of Non-stationary Strength Training Versus Traditional Strength Training: Compared the Effects of Non-stationary Strength Training on the Athletes
Purpose: Volleyball has a high influence in the world, and there are many professional volleyball players and a large number of volleyball fans in all countries.
- Trial name
- FMS、YBT、ST (NCT06831721)
- Testing
- Unstable Strength Training
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Kinesiophobia, Ankle Sprains
The Effect of Balance Training Following STARS on Postural Control
Chronic ankle instability (CAI) is defined as the symptoms continuing 12 months after the first sprain and the functional and/or mechanical instability reported by the individual.
- Conditions
- Kinesiophobia, Ankle Sprains, Sensory Deficit, Ankle Instability
- Trial name
- NCT05602233
- Testing
- Exercise, STARS (Sensory-Targeted Ankle Rehabilitation Strategies)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Anterior Cruciate Ligament Injury
The Functional Status of Anterior Cruciate Ligament Reconstruction (ACLR) Patients at Discharge From Rehabilitation
Objectives: 1. To examine the ability of ACLR patients at discharge from rehabilitation to perform a single-hop for distance. 2. To examine isometric muscle strength of ACLR patients at discharge from rehabilitation. 3.
- Trial name
- SHOPS (NCT03047187)
- Testing
- ACLR
- Volunteers
- 25 people
- Sponsor
- University of Salford
Hemiplegia and/or Hemiparesis Following Stroke, Anterior Circulation Stroke of Uncertain Pathology
Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients
The subjects will be asked to attend minimum 15 separate sessions, 6 for testing changes in reflex behaviors, 3 for testing changes in the influence of descending motor tracts on spinal motor neurons, 3 for each testing…
- Trial name
- TENS (NCT06541015)
- Testing
- InTENSity 10 TENS Stimulator
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Acute, Pain, Chronic
Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Evaluation of the effect of the AI500™ SINGLE-DOSE GEL medical device in patients with reduced knee function
- Conditions
- Pain, Acute, Pain, Chronic, Knee Injuries, Knee Osteoarthritis
- Trial name
- NCT05886608
- Testing
- AI 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Iliotibial Band Syndrome, Pain
Effects of Functional Motor Control on Pain, Flexibility, Lower Extremity Function With ITBS
The study is randomized and single-blinded. Ethical approval is taken from ethical committee of Riphah International University, Lahore.
- Conditions
- Iliotibial Band Syndrome, Pain, Flexibility
- Trial name
- NCT06131658
- Testing
- Functional motor control excercise, convectional excercise
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Muscle Weakness, Metatarsal Fracture
Comparison Different Method Treatment in Tuberosity Fractures of the Proximal Fifth Metatarsal
Fracture of the base of the fifth metatarsal is one of the most common injuries in ankle trauma. There are many conservative treatment protocols for fifth metatarsal base fractures which have up to 99% success.
- Conditions
- Muscle Weakness, Metatarsal Fracture, Healing Fracture of Bone
- Trial name
- NCT04168411
- Testing
- Symptomatic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Hip Fracture
A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients
The purpose of the study is to determine the best dose of Vitamin D to give to hip fracture patients to achieve the optimal therapeutic level.
- Trial name
- NCT00424619
- Testing
- Vitamin D2
- Volunteers
- 64 people
- Sponsor
- McMaster University