Clinical trials: Lower Extremity Function
Elevated Metabolic Cost
The Effect of Gait Training Using Virtual Reality and Real-Time Feedback on Physiological and Functional Gait Performance in Persons With a Traumatic Lower Extremity Amputation
To assess the carryover effect of an innovative new gait training program on physiological and functional gait performance in persons with a traumatic lower extremity amputation.
- Trial name
- VRVO2 (NCT01225432)
- Testing
- Gait Training
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Stroke
Functional Massage and Eccentric Exercise in Stroke Survivors (FM-EE Stroke)
Stroke is currently the leading cause of mortality in women, the second in men and the leading cause of disability in older adults.
- Trial name
- FM-EE-stroke (NCT06922149)
- Testing
- Group A Funtional massage therapy and eccentric exercise in lower limb, Group B. Eccentric exercises training
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Universitat Internacional de Catalunya
Hemiplegic Stroke
Neural Mobilization Versus PNF Hold Relax Technique on Lower Extremity in Hemiplegic Stroke
Several studies about the effects of nerve mobilizations and stretching exercises have been conducted. This study will contribute to describing the long term effects of these techniques on gait, motor function and quality of life…
- Trial name
- NCT05379998
- Testing
- Neural mobilization, PNF hold relax technique
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Cerebral Palsy, Hemiplegic Cerebral Palsy
Effects of Botulinum Toxin Injection on Sensation and Postural Control in Children With Hemiplegic Cerebral Palsy
In this study, the investigators aimed to investigate the effects of botulinum neurotoxin type A (BoNT-A) injection applied to the ankle plantar flexor muscles on lower extremity sensation and quantitative balance parameters in…
- Trial name
- NCT04940143
- Testing
- Botulinum toxin type-A (Onabotulinum toxin type-A), Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prolonged Mechanical Ventilation, Ventilator Weaning
Effects of Mobilization Using a Powered Lower-limb Exoskeleton With Prolonged Mechanical Ventilation
This study aims to evaluate the effects of powered lower-limb exoskeleton-assisted training on lower limb strength, respiratory parameters, 28-day ventilator-free days, and length of hospital stay in patients with prolonged…
- Conditions
- Prolonged Mechanical Ventilation, Ventilator Weaning, Ventilator Dependent, Exoskeleton Device
- Trial name
- NCT07445035
- Testing
- lower-limb exoskeleton, Standard medical treatment
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Fu Jen Catholic University
Hamstring Tightness, Hamstring Injury Prevention
Effects of Neurodynamic Sliding Versus Eccentric Training on Lower Extremity Function, Strength and Proprioception in Athletes with Short Hamstring Syndrome.
Hamstring strains are among the most common injuries in field sports, accounting for 10% of all team sports injuries and often leading to long-term absence from activities.
- Trial name
- NCT06748560
- Testing
- Neurodynamics, Eccentric training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Yeditepe University
Hallux Limitus
Kinetic Control Versus Dynamic Taping on First Metatarsophalangeal Joint in Athletes With Functional Hallux Limitus
This study is conducted to investigate and compare the effect of adding either kinetic control retraining or dynamic taping to the standard treatment program on first metatarsophalangeal joint dorsiflexion active range of motion…
- Trial name
- NCT07692113
- Testing
- the standard treatment, Dynamic taping, kinetic control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injury
Evaluation of the Effect of Using WeChat Applet to Intervene in the Home Functional Exercise of Patients After Anterior Cruciate Ligament Reconstruction Based on the Health Belief Model
Based on the home rehabilitation exercise of patients undergoing ACL reconstruction, the existing WeChat applet of sports medicine of the Third Hospital of Beijing Medical University is optimized to be used as a health education…
- Trial name
- NCT04957810
- Testing
- WeChat Mini Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Hip Fracture
A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients
The purpose of the study is to determine the best dose of Vitamin D to give to hip fracture patients to achieve the optimal therapeutic level.
- Trial name
- NCT00424619
- Testing
- Vitamin D2
- Volunteers
- 64 people
- Sponsor
- McMaster University
Stroke
Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise Among Stroke Patients.
Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise on Balance and Lower Limb Motor Function Among Stroke Patients.
- Trial name
- NCT07578948
- Testing
- Modified otago exercise, Task oriented progressive resistance training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Hip Fracture, Postoperative Recovery
Total Intravenous Versus Inhalational Anesthesia in Patients Undergoing Hip Fracture Surgery
This prospective observational study aims to compare total intravenous anesthesia (TIVA) with sevoflurane-based inhalational anesthesia in patients aged 65 years and older undergoing hip fracture surgery under general anesthesia.
- Trial name
- NCT07860996
- Testing
- Propofol-based Total Intravenous Anesthesia, Sevoflurane-based Inhalational Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Patellar Dislocation
The Unstable Kneecap - the Impact of Anatomy on Function
The principal objective of the study is to find out which everyday activities make the kneecap unstable in people with patellofemoral instability.
- Trial name
- SPRING (NCT02569931)
- Testing
- Gait analysis, Electromyography, Intra-operative tracking and pressure measurements
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy
Short-Term Effects of Manual Therapy Prior to Neuromotor Therapy in Children With Cerebral Palsy
This pilot study aims to evaluate the immediate, short-term biomechanical and neuromuscular effects of lower limb manual therapy applied as a preparatory phase prior to functional neuromotor rehabilitation in children with…
- Conditions
- Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy, Bilateral Spastic Cerebral Palsy, Diplegic Cerebral Palsy With Spasticity
- Trial name
- NCT07902466
- Testing
- Manual Therapy (T1 & T3)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- LIFE - Research and Care Institute - Santa Lucia IRCCS
Stroke
Effect of Thermal Stimulation for Lower Extremity Movement and Function in Patients With Stroke
The thermal stimulation have been proven effective in upper extremity of stroke patients. Therefore, this study explored the efficacy of thermal stimulation in lower extremity of stroke patients.
- Trial name
- NCT01668420
- Testing
- thermal stimulation
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Hsin-Wen Hsu
Stroke, Gait Disorder, Sensorimotor
The Effect of Body Weight Support Treadmill Training on Lower Limb Function in Patients With Chronic Stroke
Stroke has severe debilitating neurological consequences for the victim. Within context of this study, gait disturbance is induced by disabilities in muscle weakness, abnormal muscle contraction, or postural control.
- Trial name
- NCT04491162
- Testing
- Body weight support treadmill training + conventional therapy, Conventional therapy
- Where
- India
- Volunteers
- 36 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
Donor Ankle Sensorimotor Recovery After ACL Reconstruction With a Peroneus Longus Tendon Autograft
This prospective longitudinal observational cohort study will characterize recovery of donor-ankle sensorimotor function in adults who have undergone primary anterior cruciate ligament reconstruction using a peroneus longus…
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Donor Site Complication
- Trial name
- NCT07762989
- Testing
- Anterior Cruciate Ligament Reconstruction Using a Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Stroke
Unilateral Strength Training and Mirror Therapy for Chronic Stroke Patients
This is a pilot randomised controlled trial investigating a combination of unilateral strength training (cross-education) and mirror therapy for the rehabilitation of lower limb impairment following a stroke.
- Trial name
- NCT03497650
- Testing
- Mirror Therapy, Cross-Education of Strengthening.
- Where
- Ireland
- Volunteers
- 35 people
- Sponsor
- Institute of Technology, Sligo
Healthy
Effects of Blood Gas Perturbations
In this study, the effects of blood gas perturbations on neuromuscular function of the diaphragm and lower limbs at rest and during exercise will be investigated.
- Trial name
- NCT07701603
- Testing
- Gas perturbation
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology