Clinical trials: Lower Extremity Pain
Intractable Neuropathic Pain, Pain
Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity
The primary objective of this study is to compare the efficacy and patient preference for spinal cord stimulation (SCS) using the Precision device with the electrode array placed at T7 versus placement at T8.
- Conditions
- Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
- Trial name
- NCT00399841
- Testing
- Precision for Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Boston Scientific Corporation
Hip Fractures, Complication of Traction Procedure
Skin Traction Versus Position Splint in Patients With Hip Fracture
The aim of this prospective, randomized controlled trial is to compare the effects of preoperative skin traction and position splint on pain, comfort, complications, difficulty level of nursing interventions, satisfaction from…
- Conditions
- Hip Fractures, Complication of Traction Procedure, Pain, Splints
- Trial name
- NCT02287571
- Testing
- Derotation splint, elastic bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Tourniquet Pain
Ketamine Reduces Tourniquet Pain In Patients Undergoing Lower Limb Surgery Under Spinal Anaesthesia
A prospective, double blind, randomised controlled trial to evaluate the effect of ketamine in reducing tourniquet pain for patients undergoing lower limb surgery under spinal anaesthesia.
- Trial name
- NCT03357055
- Testing
- Ketamine, Normal saline
- Volunteers
- 60 people
- Sponsor
- Dr Foo Li Lian
Rehabilitation
Motor Imagery Practice on Amputees (MIPA)
Motor imagery practice (MIP), which is the repeated internal representation of a movement without engaging its physical execution and which shares a neurofunctional equivalence with physical practice, has been show to contribute…
- Trial name
- MIPA (NCT03125538)
- Testing
- Motor Imagery, Control Task
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Laboratoire Interuniversitaire de Biologie de la Motricité
Ankle Sprain
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
This study will investigate the efficacy of the Indomethacin patch in pain relief of ankle sprain in adult patients, compared to a placebo patch
- Trial name
- NCT01957215
- Testing
- Indomethacin
- Where
- 15 sites in China
- Volunteers
- 270 people
- Sponsor
- GlaxoSmithKline
Sports Physical Therapy
Effects of Post-Isometric Relaxation Technique Vs Soft Tissue Mobilization in Leg Spin Bowlers
Effects of Post-Isometric Relaxation Technique versus Cross Friction Soft Tissue Mobilization in Leg Spin Bowlers with Rotator cuff strain
- Trial name
- NCT06819397
- Testing
- post isometric relaxation, cross friction soft tissue mobilization
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Achilles Injuries Tendon, Achilles Tendinopathy (AT)
Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy
Midportion Achilles tendinopathy is a common cause of pain and functional limitation in both athletes and the general population.
- Conditions
- Achilles Injuries Tendon, Achilles Tendinopathy (AT), Achilles Tendinitis, Left Leg, Achilles Tendinitis, Right Leg
- Trial name
- NCT07483320
- Testing
- Platelet Rich Plasma, Extracorporeal Shockwave Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Spaulding Rehabilitation Hospital
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Anterior Innominate Iliosacral Dysfunction
Pelvic Stabilization Exercises & (PNF) on Pain, Disability & Functional Leg Length
The aim of the study is to compare the effects of pelvic stabilization exercises and proprioceptive neuromuscular facilitation on pain, disability and functional leg length in patients with anterior innominate iliosacral…
- Trial name
- NCT06108960
- Testing
- Proprioceptive neuromuscular facilitation, Pelvic stabilization exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Leg Pain, Ulcer
Stem Cell Study for Patients With Leg Ulcer/Gangrene
The purpose of this study is to determine if stem cell therapy with one's own cells (autologous cells) delivered intramuscularly to one's leg with ulcer and/or gangrene due to poor blood flow will be safe and if it will relieve…
- Conditions
- Leg Pain, Ulcer, Gangrene, Ischemia
- Trial name
- NCT00221143
- Testing
- Autologous peripheral blood CD34 positive cell therapy
- Where
- 2 sites in Japan
- Volunteers
- 15 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Phantom Limb Pain (PLP), Primary/Secondary Scar Hyperalgesia
A Trial of Lidocaine Patch for Lower Limb Amputation Pain
Phantom limb pain (PLP) and scar hyperalgesia (SH) are frequent problems after amputation; in particular most persons who undergo limb amputation will experience phantom pain.
- Trial name
- NCT02696720
- Testing
- Lidocaine
- Where
- 2 sites in Belgium
- Sponsor
- Brugmann University Hospital
Postoperative Pain
Peripheral Nerve Blocks for Major Lower Extremity Amputations
This study will be a double-blinded randomized controlled trial analyzing all patients who will undergo major lower extremity amputations by the vascular surgery service at University of California, San Francisco (UCSF) Fresno…
- Trial name
- NCT03174782
- Testing
- Bupivacaine, Saline Solution
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Venous Stasis Ulcers
Provant Therapy of Venous Stasis Ulcer Trial
This pilot study hypothesizes that use of the Regenesis Provant Wound Therapy System (a radiofrequency device) twice daily over venous stasis ulcers (wounds thought to occur due to improper functioning of valves in the veins…
- Trial name
- NCT01050023
- Testing
- Provant Device (Wound Therapy System), Provant Device - Inactive
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Southern California Institute for Research and Education
Neck Pain
The Effect of Lower Limbs Neural Mobilization in Subjects With Cervical Pain.
No studies have investigated the effects of a Sciatic nerve mobilization in subjects with neck pain. This study aims to determine the immediate effects of a lower limbs neural mobilization on cervical range of motion and on the…
- Trial name
- NCT03603054
- Testing
- Active neck mobilization, Active Mobilization of the sciatic nerve
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Hip Injuries, Hip Dislocation
Does Limb Pre-Conditioning Reduce Pain After Hip Arthroscopy
The purpose of this study is to determine if the utilization of Ischemic Pre-Conditioning 24-hours prior to hip arthroscopy decreases patient's post-operative pain and opioid consumption.
- Conditions
- Hip Injuries, Hip Dislocation, Hip Fractures
- Trial name
- NCT04925791
- Testing
- standardized pre-conditioning treatment, Partial occlusion
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Lumbar Radiculopathy
Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties.
- Trial name
- NCT07726823
- Testing
- Mulligan Bent Leg Raise (MBLR), Spinal Mobilization With Leg Movement (SMWLM)
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Low Back Pain
Effect of Hamstring Stretching and Neural Mobilization on Range of Motion and Low Back Pain
This study was designed to answer 3 primary research questions: 1. In adults with low back pain, reduced SLR ROM (Range of Motion) and a positive sensitized SLR (Straight leg raise) test, does neurodynamic mobilization result in…
- Trial name
- NCT01483573
- Testing
- neural mobilization, straight leg raise
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Myofascial Pain Syndromes
Does Self-myofascial Release With a Foam Roll Change Pressure Pain Thresholds in Lower Extremity Muscles
The purpose of this study was to examine the effects of a foam rolling intervention on pressure pain thresholds (PPT) of the ipsilateral antagonist and contralateral muscle groups.
- Trial name
- NCT02924259
- Testing
- The GRID foam roll
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- California State University, Dominguez Hills
Muscle Soreness
A Within-subject Study to Evaluate the Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness
This study will assess the analgesic efficacy of DSG 1% compared to placebo in the reduction of the pain associated with DOMS
- Trial name
- NCT02271854
- Testing
- Diclofenac sodium gel 1%
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Novartis