Clinical trials: Lower Extremity Pain
Pes Planus
Comparison of Navicular Mobilization and Rigid Tape in Pes Planus
Pes planus, sometimes known as flat feet, is one of these disorders and is characterized by a collapsed medial longitudinal arch, hindfoot eversion, and forefoot abduction.
- Trial name
- NCT05354180
- Testing
- navicular mobilization, rigid tapping, Navicular Mobilization and Rigid Taping
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Riphah International University
Hip Fractures, Acute Pain
PENG Block for Traumatic Hip Fracture in the Emergency Department
The study is a multicenter single-blinded randomized comparative trial. Adult patients older than 20 years of age presenting with acute hip fracture in emergency department between January 1st, 2021 and December 31st, 2021 will…
- Conditions
- Hip Fractures, Acute Pain, Emergency Department
- Trial name
- NCT04997785
- Testing
- Ultrasound-guided Pericapsular Nerve Group (PENG) Block
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Dalin Tzu Chi General Hospital
Venous Leg Ulcer
Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison of the Efficacy and Safety of Two Dressings Urgotul and TulleGras
Evaluation of the non-inferiority of TulleGras M.S.® versus Urgotul® in pain associated with removal of wound dressing during care of venous leg ulcer
- Trial name
- NCT02104180
- Testing
- Urgotul, TulleGras M.S.
- Where
- 27 sites in France
- Volunteers
- 62 people
- Sponsor
- Mylan Inc.
Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80
Parasacral Ischial Plane Block in Lower Extremity Surgery
The parasacral ischial plane block is a novel fascial plane approach targeting the sacral plexus. This technique is technically less challenging and eliminates the requirement for direct visualization of the sacral plexus.
- Conditions
- Patients Scheduled for Elective Lower Extremity Surgery, Ages 18-80, ASA I-III, Patients Operated on Under Regional Anesthesia
- Trial name
- NCT07594197
- Testing
- Parasacral Ischial Plan Block, Sacral plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Hip Fractures
Fascia Iliaca Compartment Block for Pain Management in Hip Fracture Patients
BLOCKPAIN is a randomized controlled study, 80 participants. The participants will be hip fracture patients in Emergency Medicine Department in Clinical Hospital "Sveti Duh", Zagreb, Croatia.
- Trial name
- BLOCKPAIN (NCT04837924)
- Testing
- fascia iliaca compartment block, (FICB) (levobupivacaine hydrochloride 0,25% 40 ml), paracetamol 1 gram IV, Rescue analgesic tramadol 100 mg IV if needed
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- General Hospital Sveti Duh
Amputees
Effectivity of Motor Imagery and MirrorTherapy in Amputees
This study evaluates the effectiveness of imagery motor on phantom pain and amputation process
- Trial name
- NCT02761447
- Testing
- Treatment Traditional and Imaginary Motor Program, Treatment Traditional and Mirror Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Almeria
Chronic Pain
Frequency of Piriformis Syndrome:Does the Presence of One Pathology Rule Out the Other?
The purpose of the investigators is to determine the frequency of priformis syndrome in patients presenting with hip and/or leg pain and to investigate the association of Priformis syndrome with other pathologies of the lumbar…
- Trial name
- NCT05450913
- Testing
- Priformis intramuscular injection with %2 lidocain
- Volunteers
- 100 people
- Sponsor
- Diskapi Teaching and Research Hospital
Local Hypoalgesia, Distal Hypoalgesia
Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions
This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training…
- Conditions
- Local Hypoalgesia, Distal Hypoalgesia, Resistance Training, Pressure Pain Thresholds
- Trial name
- NCT06765486
- Testing
- Lower limb resistance training, Upper limb resistance training
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Intractable Neuropathic Pain, Pain
Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity
The primary objective of this study is to compare the efficacy and patient preference for spinal cord stimulation (SCS) using the Precision device with the electrode array placed at T7 versus placement at T8.
- Conditions
- Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
- Trial name
- NCT00399841
- Testing
- Precision for Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Boston Scientific Corporation
Vibration Therapy, Anterior Cruciate Ligament Injuries
Investigation of the Effects of Vibration Therapy on Pain, Functionality, and Proprioception After ACL Injury
Over the past decade, vibration therapy has gained popularity. This treatment involves the transmission of vibration either through whole-body vibration (WBV) platforms or by applying local vibration (LV) directly to the muscles…
- Trial name
- NCT06185231
- Testing
- Percussion Massage Group, Conventional Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
Critical Limb Ischemia, Ischemia
VEGF Gene Transfer for Critical Limb Ischemia
The purpose of this gene therapy study is to evaluate the safety and efficacy of intramuscular gene transfer using Vascular Endothelial Growth Factor (VEGF) or placebo in patients with moderate to high-risk Critical Limb Ischemia…
- Conditions
- Critical Limb Ischemia, Ischemia, Leg Ulcer
- Trial name
- NCT00304837
- Testing
- pVGI.1 (VEGF-2)
- Where
- 3 sites in United States
- Sponsor
- Losordo, Douglas, M.D.
Xerosis Cutis, Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Effectiveness of CBD for Neuropathic Pain in Diabetic Foot Neuropathy
Evaluation of cannabidiol and urea 10%.
- Trial name
- NCT07162454
- Testing
- Group 1. Complete formula, Group 2. Cannabidiol and Urea 10% formula.
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidad Complutense de Madrid
Overuse Injury, Lower Extremity Problem
Step Rate Retraining to Reduce Injury and Disability (STRIDe)
This study will be the first project to evaluate the effectiveness of wearable technology (Garmin Forerunner35) while performing gait retraining in field on military members.
- Conditions
- Overuse Injury, Lower Extremity Problem, Stress Injury, Repetitive, Patellofemoral Pain Syndrome
- Trial name
- STRIDe (NCT04747223)
- Testing
- Run Gait Retraining
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army-Baylor University Doctoral Program in Physical Therapy
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Patellofemoral Pain Syndrome, Hallux Valgus
The Additional Effect of Hallux Valgus Correction on Runners With First Ray Instability and Patellofemoral Pain Syndrome
The study purpose is to investigate the effectiveness of a program combining biomechanical taping with lower extremity neuromuscular exercises for runners with patellofemoral pain syndrome (PFPS) and hallux valgus
- Trial name
- NCT03468491
- Testing
- combined training, Proximal training
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Pain, Hip Fracture
PENG vs. FIC Block for Hip Fracture ED Patients
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1.
- Trial name
- NCT05102760
- Testing
- Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Antonios Likourezos
Chronic Postsurgical Pain
CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures
The purpose of this study is to assess the proteomics and transcriptomic differences between pain-free control subjects and patients with chronic postoperative pain through single-cell sequencing technology.
- Trial name
- NCT06126289
- Volunteers
- 20 people
- Sponsor
- Xuzhou Central Hospital
Ankle Sprains, Ankle Fractures
Accumulative Effects of Talus Mobilization
The purpose of this study is to verify the effect of anteroposterior talus mobilization on range of motion, pain, and functional capacity in participants with sub-acute and chronic ankle injuries.
- Conditions
- Ankle Sprains, Ankle Fractures, Ankle Dislocations, Ankle Bruises
- Trial name
- NCT02244008
- Testing
- joint mobilization, manual contact
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of Minas Gerais
Spinal Stenosis, Low Back Pain
Total Facet Arthroplasty System®(TFAS®) Clinical Trial
The Archus Total Facet Arthroplasty System® (TFAS®) is a non-fusion spinal implant indicated for treatment of patients with moderate to severe spinal stenosis. TFAS® replaces the diseased facets following surgical removal.
- Conditions
- Spinal Stenosis, Low Back Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00418197
- Testing
- Total Facet Arthroplasty System® (TFAS®)
- Volunteers
- 450 people
- Sponsor
- Archus Orthopedics, Inc.
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University