Clinical trials: Lower Extremity Pain
Edema Leg, Pain
Does Edema Affect the Adjustment of TENS Amplitude
The goal of this pre-post clinical trial is to compare the amplitude settings of three different frequency TENS modes (Conventional TENS, LF TENS, HF TENS) in patients who had undergone total knee arthroplasty, both with the…
- Trial name
- NCT06153277
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Karamanoğlu Mehmetbey University
Phantom Pain
Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain
Phantom limb pain (PLP) is as painful sensations located to the missing limb and classified as neuropathic pain. In the United States, an estimated 1.7 million patients have undergone limb amputation, and 60% to 80% of these…
- Trial name
- NCT02311777
- Testing
- Pregabalin, Ketamine
- Where
- 2 sites in United States
- Sponsor
- University of Texas Southwestern Medical Center
Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI
Knee Pain Relief After Endovenous Treatment for Lower Limb Varicose Veins: A Prospective Observational Study
This study will observe patients with lower limb varicose veins who also have knee pain. Many patients with varicose veins experience swelling, heaviness, or aching in the legs, and some also report pain in or around the knee.
- Conditions
- Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI, Knee Pain Chronic, Knee Osteoarthritis
- Trial name
- VV-KNEE (NCT07163312)
- Testing
- Endovenous Ablation for Varicose Veins
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Lower Limb Surgery, Pain
Role of Perineural Catheter in Pain Control and Opioid Consumption After Major Amputation of Lower Limb
The goal of this randomized controlled clinical trial is to evaluate the effectiveness of postoperative bupivacaine infusion through a perineural catheter in managing postoperative pain and to determine the opioid consumption…
- Conditions
- Lower Limb Surgery, Pain, Phantom Limb Pain After Amputation, Stump Pain
- Trial name
- NCT07896798
- Testing
- Bubpivacaine, Tramadol, Saline
- Volunteers
- 96 people
- Sponsor
- Aga Khan University
Pain, Acute, Postoperative Pain
Use of Dexamethasone Via Two Different Methods in PENG Block
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule.
- Conditions
- Pain, Acute, Postoperative Pain, Hip Fractures
- Trial name
- NCT06242028
- Testing
- Group P, Group S
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ondokuz Mayıs University
Amputation of Lower Limb
Gabapentin in Phantom and Stump Pain
To investigate whether gabapentin can prevent phantom and stump pain after amputation.
- Trial name
- NCT00169013
- Testing
- Gabapentin
- Where
- Denmark
- Sponsor
- Danish Pain Research Center
Sciatic Leg Pain
Neurodynamic Study
Sciatica is a debilitating and costly condition. Prognostically, patients presenting with leg pain often have a poor recovery and some go onto have spinal surgery.
- Trial name
- NCT03144362
- Testing
- Bilateral Sliding Techniques, Unilateral Sliding Techniques
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Diabetic Foot Ulcer
Shockwave Therapy of Chronic Diabetic Foot Ulcers
Introduction: Foot ulcers are a feared complication among diabetic patients. The ulcers can cause pain, discomfort and reduced quality of life. The development of foot ulcers places the patients at a risk of amputation.
- Trial name
- NCT02251418
- Testing
- Extracorporeal shockwave therapy
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Odense University Hospital
Pain, Hip Fractures
Comparison Effects of Two Regional Anesthetic Technique on Pain During High Risk Hip Fracture Surgery
In this study, our is to compare effect of lumbosacral plexus and sacral plexus + suprainguinal fascia iliaca plane block on perioperative pain via analgesia nociceptive index monitor on high-risk patients undergoing hip fracture…
- Conditions
- Pain, Hip Fractures, Perioperative Analgesia
- Trial name
- NCT05862922
- Testing
- Analgesia Nosiception İndex Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Femur Fracture, Pain, Joint
Emergency Department Management of Femur Fractures
Comparison of emergency department management of patients presenting with isolated hip fracture: comparison of methods used in pain management, monitoring, and treatment; comparison of hospitalization durations; comparison of…
- Conditions
- Femur Fracture, Pain, Joint, Analgesia
- Trial name
- NCT06531564
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- Saglik Bilimleri Universitesi
Venous Leg Ulcer
Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy
The laser emits an infrared light that heats the skin and underlying tissues with the purpose of temporary relief of minor muscle and joint pain, as well as stiffness associated with arthritis.
- Trial name
- NCT03716167
- Testing
- Summus Laser
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Failed Back Surgery Syndrome
Efficacy Study of the Octapolar Lead in Patients With Failed Back Surgery Syndrome (FBSS) With Chronic Pain
Spinal cord stimulation (SCS) has been used for over 40 years to treat neuropathic pain. Various clinical studies have shown a beneficial effect of SCS on pain in patients with Failed Back Surgery Syndrome (FBSS).
- Trial name
- NCT01096147
- Testing
- Spinal cord stimulation with eight polar electrode
- Where
- 8 sites in Belgium, Norway and 1 more
- Volunteers
- 80 people
- Sponsor
- Rik Buschman, PhD
Femoral Neck Fractures, Blood Loss, Surgical
Effect of Regional Anesthesia Techniques on Perioperative Blood Loss in Femoral Neck Fracture Surgery
This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery.
- Conditions
- Femoral Neck Fractures, Blood Loss, Surgical, Postoperative Pain
- Trial name
- NCT07702084
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain
Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery
Nerve blocks are used to decrease the amount of pain you have after surgery. We are asking you to take part in a research study.
- Trial name
- NCT01986751
- Testing
- Clonidine, ropivacaine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Rheumatoid Arthritis
Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain
This study will assess the outcomes of three currently available regenerative treatments (FloGraft, autologous stem cell therapy, platelet rich plasma therapy) for painful degenerative conditions of the joints.
- Trial name
- NCT01978639
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Arizona Pain Specialists
Phantom Limb Pain, Phantom Pain
Study of Lower-limb Phantom Pain Syndrome Using Peripheral Nerve and Spinal Cord Stimulation
Brief Summary: The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation, Lower Limb Amputation
- Trial name
- NCT05807607
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and daily modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation, Change according to the scale of the PainDetect questionnaire
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Hip Fractures, Anesthesia Local
Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Postoperative
- Trial name
- NCT02255591
- Testing
- Lidocaine-adrenaline added gadolinium.
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Knee Injuries
Impact of a Bike Fitting Assessment and Interventions by a Physiotherapist in Recreational Cyclists With Knee Pain.
Background Cycling is a very popular activity and has various health benefits. Knee pain is very common among recreational cyclists and often limits cyclists to perform their sport.
- Trial name
- NCT05713656
- Testing
- Physiotherapy care
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
The Foot Exercises in Patellofemoral Pain
The purpose of this study is to investigate the additional effects of Short Foot Exercises on pain, biomechanical characteristics and functionality of lower extremity in patients with patellofemoral pain.
- Conditions
- Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome, Pronation Deformity of the Foot, Exercise
- Trial name
- NCT03099512
- Testing
- SFE, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University