Clinical trials: Lower Extremity Pain
Musculoskeletal Pain
Real and Sham Diathermy vs Hand Massage in Lower Limbs Delayed Onset Muscle Soreness (DOMS)Effect on Knee Proprioception
Delayed onset muscle soreness (DOMS) can have an impact on the proprioception of knee joint . The study aim is to assess the effect of manual massage, diathermy and sham diathermy the proprioception of the knee joint in patients…
- Trial name
- NCT02693678
- Testing
- Massage, DIathermy
- Volunteers
- 24 people
- Sponsor
- Studi Fisioterapici di Montagna
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Painful Diabetic Neuropathy
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression
The UT Southwestern Medical Center at Dallas would like to give you information about a research study that is being done for patients with painful diabetic neuropathy and have not responded to medical treatment.
- Trial name
- DNND (NCT00703209)
- Testing
- Nerve Decompression
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Ankle Sprain
NMES With PNF for Ankle Sprain Rehabilitation
Ankle sprains are one of the most common sports injuries. In some people, they can lead to chronic ankle problems that affect daily life and sports performance.
- Trial name
- NCT07190599
- Testing
- Proprioceptive neuromuscular facilitation (PNF) with neuromuscular electrical stimulation (NMES), Proprioceptive neuromuscular facilitation (PNF) only
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fooyin University
Anterior Cruciate Ligament Injury, Patellofemoral Pain Syndrome
Sports Rehabilitation Therapy for Knee Joint Sports Injuries: A Case Study of Anterior Cruciate Ligament Injury and Patellar Chondromalacia
The primary objective of this clinical trial is to verify the superiority of a digital diagnosis and treatment system for the conservative management of knee sports injuries-based on wearable sensors, machine vision, and large…
- Trial name
- NCT07423819
- Testing
- Muscle Strength Training, Lower limb balance and stability exercises, Stretching and Relaxation
- Where
- 4 sites in China
- Volunteers
- 160 people
- Sponsor
- Peking University Third Hospital
Ankle Sprain, Back Pain
Counterpain PXM Versus Diclofenac Versus Piroxicam
The goal of this clinical trial is to learn if a gel containing Piroxicam plus Counterirritant (warming/cooling ingredients) is as effective and safe as two other common anti-inflammatory gels for treating acute muscle, bone, and…
- Conditions
- Ankle Sprain, Back Pain, Osteoarthritis (OA) of the Knee, Tennis Elbow
- Trial name
- NCT07475663
- Testing
- Piroxicam plus Counterirritant (brand name Counterpain® PXM)., Diclofenac Sodium 10 mg (Brand Name Hotin® DCL), Piroxicam 0.5% (Brand name Pirofel® gel)
- Where
- Indonesia
- Volunteers
- 180 people
- Sponsor
- Taisho Pharmaceutical Indonesia
Ankle Fractures, Distal Radius Fracture
Nerve Block for Pain Control After Fracture Surgery
Surgical treatment for patients with a fracture of the ankle or distal radius is commonly offered on an outpatient basis. Patients are routinely discharged from hospital within 4 hours of their procedure.
- Trial name
- NCT05391464
- Testing
- Peripheral Nerve Block
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- MaineGeneral Health
Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee
Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System
This study tests whether a vibration-based feedback device (Suralis) can reduce phantom limb pain in people with lower-leg amputations over 3 weeks.
- Conditions
- Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee, Lower Limb Amputation Below Knee, Lower Limb Amputation Knee
- Trial name
- NCT07324109
- Testing
- Vibrotactile sensory feedback
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Median
Chronic Pain
Study of PM Modulation Therapy in Trial Phase
Trialing of PM modulation therapy in patients with chronic intractable low back pain
- Trial name
- NCT03110601
- Testing
- Control - Conventional SCS, Test - Stimgenics SCS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stimgenics LLC
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
Knee osteoarthritis is a complex condition, and selecting effective non-drug treatments like orthoses or exercise is often difficult and imprecise.
- Trial name
- MathKOA (NCT07134244)
- Where
- 2 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Non-specific Low Back Pain (NSLBP)
Mulligan Mobilization Techniques for Non-Specific Low Back Pain
This study aims to compare the effectiveness of two different Mulligan mobilization techniques in patients with non-specific low back pain.
- Trial name
- NCT07181395
- Testing
- Hip Internal Rotation Mulligan Mobilization, Straight Leg Raise Mulligan Mobilization, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Chronic Pain, Intractable Pain
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Study to evaluate the effectiveness of time variant pulse (TVP)-SCS in patients with chronic pain using commercially approved Boston Scientific SCS Systems per local Instructions for use (IFU).
- Conditions
- Chronic Pain, Intractable Pain, Low Back Pain, Chronic Low-back Pain
- Trial name
- MOSAIC (NCT07190807)
- Testing
- Boston Scientific WaveWriter Alpha™ SCS Systems
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- Boston Scientific Corporation
Hip Fractures, Pain, Acute
PENG: an Estimation of ED50 in Neck of Femur Fracture
The effective dose of local anaesthetic used in PENG blocks to achieve analgesia in patients with fractured neck of femur is unknown.
- Trial name
- NCT05095025
- Testing
- Bupivacaine Hydrochloride 20ml injectate
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- University College Cork
Hip Fractures, Analgesia
Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block
The investigators propose to investigate the effect of intraoperative FICB and intrafragmentary fracture blockade on postoperative pain and opiate consumption using a randomized controlled trial study design.
- Conditions
- Hip Fractures, Analgesia, Opioid Use, Pain, Postoperative
- Trial name
- NCT04335461
- Testing
- Cephalomedullary nailing of extracapsular hip fracture, cephalomedullary nail, Regional Anesthetics
- Where
- United States
- Sponsor
- Montefiore Medical Center
Critical Limb Ischemia, Peripheral Arterial Disease
ALD-301 for Critical Limb Ischemia, Randomized Trial
This study will treat patients with such severe lower leg ischemia or vascular compromise that they have pain at rest. The goal is to compare treatment of the patient's painful disorder by injecting cells into the calf of the leg…
- Conditions
- Critical Limb Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
- Trial name
- CLI-001 (NCT00392509)
- Testing
- ALDH-br bone marrow cells vs. mononuclear bone marrow cells
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Aldagen
Low Back Pain
Manual Therapy as a Form of Sensory Discrimination in Chronic Low Back Pain
This study evaluates whether different explanations given to patients with long lasting back pain influence a physical therapy treatment technique.
- Trial name
- NCT02757378
- Testing
- Neuroplasticity Explanation (Experimental), Biomechanical Explanation (Control)
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Kevin Farrell
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Hip Fractures, Pain, Postoperative
The Effect of TENS on Pain and Analgesic Consumption
The surgical treatment of an individual with osteoarthritis and hip fracture is provided by hip replacement surgery. While restructuring the joint surfaces with surgery, it is aimed to provide both hip joint movements and to…
- Conditions
- Hip Fractures, Pain, Postoperative, Analgesia
- Trial name
- NCT05939804
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Knee Pain
Anterior Knee Pain After Tibial Nailing
Anterior knee pain (AKP) is a common complication following intramedullary (IM) nailing of a tibial shaft fracture. The purpose of this prospective study was to determine if there is an association between AKP and nail position.
- Trial name
- NCT01106963
- Testing
- Tibial intramedullary nailing
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb