Clinical trials: Lower Extremity Pain
Ankle Sprains
Manual Therapy, Kinesiotape and Strength Training in Soccer Players With Recurrent Ankle Sprains
Introduction. The ankle sprain is one of the most prevalent injuries in soccer players. The muscle strength deficit is one of the variables that can most influence the development of a sprain.
- Trial name
- NCT04257916
- Testing
- Experimental, Manual therapy group
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Knee Osteoarthritis, Knee Injuries
Dronabinol After Arthroscopic Surgery
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee.
- Conditions
- Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee
- Trial name
- NCT05335252
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Other Acute Postoperative Pain, Pain, Postoperative
Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
This trial is a part of the project: 'A novel technique for reliable, precise and safe postoperative pain management' (project no. 65-2014-3).
- Conditions
- Other Acute Postoperative Pain, Pain, Postoperative, Anaesthesia
- Trial name
- NCT02801799
- Testing
- Varying infusion rates of Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Anterior Cruciate Ligament Injuries, Postoperative Pain
Postoperative Analgesic Efficacy of ACB+iPACK vs FTB+Selective Tibial+Obturator Blocks in ACL Reconstruction
This prospective, comparative study aims to evaluate the postoperative analgesic efficacy of ultrasound-guided Adductor Canal Block (ACB) combined with iPACK block versus Femoral Triangle Block (FTB) combined with selective…
- Trial name
- ACL-Analgesia (NCT07702552)
- Testing
- Ultrasound-guided Adductor Canal Block (ACB), Ultrasound-guided iPACK block, Ultrasound-guided Femoral Triangle Block (FTB)
- Volunteers
- 100 people
- Sponsor
- Da Nang Hospital
Cellulitis of Leg
Cellulitis Optimal Antibiotic Treatment
To determine whether a short course of oral flucloxacillin (5 days) is non-inferior to a standard course (7 days) in terms of pain over days 6-14 (indicative of persistence or recurrence associated with the symptoms of most…
- Trial name
- COAT (NCT05584007)
- Testing
- Flucloxacillin Only Product in Oral Dose Form
- Where
- United Kingdom
- Volunteers
- 334 people
- Sponsor
- University of Southampton
Low Back Pain
Personalisation of Prosthetic Care for Lower- Limb Amputees
The global rise in lower-limb amputations is mainly due to diabetes and vascular complications. Amputations cause serious physical and psycho-social disabilities which impair locomotion and compromise patients quality of life.
- Trial name
- NCT06243549
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Bath
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Compartment Syndrome of Leg
Botox for the Treatment of Chronic Exertional Compartment Syndrome
After diagnosis of Chronic Exertional Compartment Syndrome (CECS), the participants will be referred to both physical therapy and Botox injection.
- Trial name
- NCT03922139
- Testing
- OnabotulinumtoxinA Injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Peripheral Artery Disease, Severe Intermittent Claudication
Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)
The goal of the study is to determine the safety and possible effectiveness of various doses of autologous (one's own) stem cells, delivered with a needle into the regions of the leg with poor blood flow in patients with blocked…
- Trial name
- NCT00311805
- Testing
- Autologous Stem Cells (CD34+)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Losordo, Douglas, M.D.
Restless Leg Syndrome (RLS)
Combined Effects of Near-Infrared Light and Vibration on Diabetic Patients With Restless Leg Syndrome
This Randomized Clinical Trial, titled "Combined Effects of Near-Infrared Light and Vibration on Pain, Sleep Quality and Symptom Severity in Diabetic Patients with Restless Leg Syndrome," aims to evaluate a non-pharmacological…
- Trial name
- NCT07308080
- Testing
- Near-Infrared Light Therapy, Vibration, Conventional Physical Therapy
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Postoperative Pain
Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Hip fracture is a common orthopedic emergency in the elderly and causes significant morbidity and is associated with mortality. In most patients, surgical reduction and fixation is the definitive treatment.
- Trial name
- NCT06132308
- Testing
- PENG Block with 0.25% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Anesthesia, Pain, Postoperative
Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac
This study aims to compare two groups of post-orthopedic patients who received a standard regimen, namely ketorolac 30mg, to the second group, which was given the standard regimen and adjuvant magnesium sulfate 30mg/kgBW 1 hour…
- Conditions
- Anesthesia, Pain, Postoperative, Surgery, Opioid Use
- Trial name
- NCT05609955
- Testing
- MgSO4
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Pes Planus
Effects of Intrinsic Muscles Training on Pain, Balance and Foot Function in Patients With Pes Planus
The study was conducted to determine the Effects of intrinsic muscles training on pain, balance and foot function in patients with Pes Planus
- Trial name
- NCT07426887
- Testing
- Intrinsic Muscles Training, conventional therapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Perfusion; Complications, Wound; Foot
Avazzia-University of Texas Southwestern Medical Center-Tennant Biomodulator® PRO Perfusion Study
This study is an open label trial designed to test the effectiveness of the Tennant Biomodulator® PRO electrical stimulation device (Avazzia), which uses BEST™ (Bio-Electric Stimulation Technology), on hospital in-patients to…
- Trial name
- NCT03843307
- Testing
- Avazzia Tennant Biomodulator® PRO
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Avazzia, Inc
Hemophilia
Central Sensitisation in Patients With Haemophilia and Degenerative Arthropathy
Introduction: Hemophilic arthropathy is characterized by functional impairments, disabling physical sequelae, and chronic pain. Central pain sensitization describes increased neural excitability characterized by spontaneous or…
- Trial name
- NCT07110675
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Tibial Plateau Fracture, Pain, Postoperative
Duloxetine Tibial Plateau
The purpose of this study is to determine if Duloxetine provides effective pain management for adult patients (18 or older) undergoing tibial plateau surgery.
- Trial name
- NCT04639011
- Testing
- Duloxetine, Standard of care (SOC) for tibial plateau surgery
- Where
- 2 sites in United States
- Sponsor
- Boston Medical Center
Hip Fractures, Acute Pain
PENG Block for Traumatic Hip Fracture in the Emergency Department
The study is a multicenter single-blinded randomized comparative trial. Adult patients older than 20 years of age presenting with acute hip fracture in emergency department between January 1st, 2021 and December 31st, 2021 will…
- Conditions
- Hip Fractures, Acute Pain, Emergency Department
- Trial name
- NCT04997785
- Testing
- Ultrasound-guided Pericapsular Nerve Group (PENG) Block
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Dalin Tzu Chi General Hospital
Musculoskeletal Pain, Low Back Pain
Group-based Exercise Training Programs for Military Members With Musculoskeletal Conditions
This randomized controlled trial will compare the mid- and long-term effects of group-based training programs with usual individual physiotherapy care for the treatment of musculoskeletal disorders in military.
- Conditions
- Musculoskeletal Pain, Low Back Pain, Rotator Cuff Tendinitis, Patellofemoral Pain Syndrome
- Trial name
- NCT05235152
- Testing
- Usual individual physiotherapy care, Group-supervised physiotherapy training programs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Laval University
Radiculopathy, Lower Extremity Radicular Pain
Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
The investigators hypothesize that there may exist different quantitative sensory profiles between radicular pain patients who respond and those who do not respond to the standard therapy of epidural steroid injections (ESI).
- Trial name
- NCT02130258
- Testing
- Quantitative Sensory Testing (QST), Epidural Steroid Injection (ESI)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital