Clinical trials: Lower Extremity Pain
Ankle Sprain
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
This study will investigate the efficacy of the Indomethacin patch in pain relief of ankle sprain in adult patients, compared to a placebo patch
- Trial name
- NCT01957215
- Testing
- Indomethacin
- Where
- 15 sites in China
- Volunteers
- 270 people
- Sponsor
- GlaxoSmithKline
Stump Neuroma, Residual Limb Pain
Ultrasound-Guided Radiofrequency Ablation Versus Steroid Injection for Stump Neuroma
This prospective clinical study aims to compare the effectiveness of ultrasound-guided radiofrequency ablation and ultrasound-guided corticosteroid injection in individuals with symptomatic stump neuroma following lower extremity…
- Conditions
- Stump Neuroma, Residual Limb Pain, Lower Extremity Amputation
- Trial name
- NCT07431424
- Testing
- Radiofrequency ablation alone, Corticosteroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Anterior Innominate Iliosacral Dysfunction
Pelvic Stabilization Exercises & (PNF) on Pain, Disability & Functional Leg Length
The aim of the study is to compare the effects of pelvic stabilization exercises and proprioceptive neuromuscular facilitation on pain, disability and functional leg length in patients with anterior innominate iliosacral…
- Trial name
- NCT06108960
- Testing
- Proprioceptive neuromuscular facilitation, Pelvic stabilization exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Knee Injuries
Impact of a Bike Fitting Assessment and Interventions by a Physiotherapist in Recreational Cyclists With Knee Pain.
Background Cycling is a very popular activity and has various health benefits. Knee pain is very common among recreational cyclists and often limits cyclists to perform their sport.
- Trial name
- NCT05713656
- Testing
- Physiotherapy care
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Hip Fractures
Transcutaneous Electrical Nerve Stimulation on Pain Intensity of Patients With Hip Arthroplasty
Fifty patients with hip arthroplasty were purposively recruited for the study. They were allocated into two groups randomly with equal number. One group had TEN, other served as control.
- Trial name
- TENSHIParth (NCT03534999)
- Testing
- Experimental. This was the group that received TENS, No intervention
- Where
- Nigeria
- Volunteers
- 50 people
- Sponsor
- Obafemi Awolowo University
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Altius Peripheral Nerve Stimulation in Amputees After TMR/RPNI
This is a single-center, prospective, within-subject study. This study seeks to enroll a total of 32 prospective subjects who will undergo surgical implantation of the FDA-approved Altius® system.
- Trial name
- NCT07571239
- Testing
- Surgical Implantation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Anterior Cruciate Ligament Rupture, Pain, Postoperative
Effect of LIA on Postoperative Pain Following ACL Reconstruction
An anterior cruciate ligament (ACL) rupture is one of the most common sport injuries, which typically develops after a sudden knee torsion.
- Trial name
- NCT03873077
- Testing
- local infiltration analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Phantom Limb Pain
Study to Assess the Efficacy of Direct Observation and Mental Visualization of Foot Movements to Treat Bilateral Lower Limb Phantom Limb Pain
Because bilateral lower extremity amputees do not have an intact limb for use with the mirror, we are now proposing to conduct a pilot trial of two treatments for phantom limb pain (PLP) - direct observation of another person's…
- Trial name
- NCT00639431
- Testing
- direct observation, mental visualization
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Subtle Cavus Foot, Mechanical Foot Pains
Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot
As off-the-counter foot orthoses are readily available and have an economic advantage, they are increasingly being used by healthcare professionals to treat mechanical foot pains in place of custom foot orthosis.
- Conditions
- Subtle Cavus Foot, Mechanical Foot Pains, Plantar Fasciitis, Achilles Tendinopathy
- Trial name
- NCT04941469
- Testing
- Specifically optimized off-the-counter foot orthosis (Medical grade foot orthosis), Plain off-the-counter foot orthosis (Medical grade foot orthosis)
- Where
- Singapore
- Volunteers
- 29 people
- Sponsor
- Tan Tock Seng Hospital
Femoral Neck Fractures
This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of…
- Trial name
- NCT05023369
- Testing
- Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Leg Pain, Back Pain
Validating PROMIS Instruments in Back and Leg Pain
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Trial name
- NCT00784251
- Where
- 2 sites in United States
- Volunteers
- 226 people
- Sponsor
- University of Washington
Injuries, Injury Arm
Virtual Reality for Pain in Acute Orthopedic Injuries
The goal of this study is to pilot test a skills-based virtual reality (VR) for acute orthopedic injury. It will measure the feasibility, signals of improvement, exploratory pain mechanisms, and user experience of an established…
- Conditions
- Injuries, Injury Arm, Injury;Sports, Injury, Knee
- Trial name
- NCT05552430
- Testing
- RelieveVRx
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Phantom Limb Pain
Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb.
- Trial name
- NCT05296265
- Testing
- VR treatment for phantom limb pain
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- Albert Einstein Healthcare Network
Intermittent Claudication, Peripheral Vascular Disease
Extract of Ginkgo Biloba (EGB 761) and Vascular Function
This study will determine if a highly standardized herbal extract of the leaves of the Ginkgo Biloba tree will benefit patients who have pain on walking due to narrowing of the arteries of the legs.
- Trial name
- NCT00029991
- Testing
- Gingko Biloba (Herb)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Sciatic Leg Pain
Neurodynamic Study
Sciatica is a debilitating and costly condition. Prognostically, patients presenting with leg pain often have a poor recovery and some go onto have spinal surgery.
- Trial name
- NCT03144362
- Testing
- Bilateral Sliding Techniques, Unilateral Sliding Techniques
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Degenerative Joint Disease, Osteoarthritis
Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery
This study is to determine the relevancy of clinical scales for outcome measures as compared to flexion angle and other gait measures.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder
- Trial name
- TKR (NCT01379118)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees, 90-Day
The goals of this study are to provide sensory information to amputees and reduce phantom limb pain via electrical stimulation of the lumbar spinal cord and spinal nerves.
- Trial name
- SCS-90 (NCT04547582)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lee Fisher, PhD
Pain, Postoperative
Preoperative Pain Catastrophizing and Its Association With Postoperative Pain After Lower Limb Trauma Surgery
The Pain Catastrophizing Scale (PCS) is a psychometric tool to identify PC. A positive correlation between PCS scores and various pain outcomes has been reported in acute and chronic pain settings.
- Trial name
- NCT03758560
- Testing
- Pre-operative Nepali version of pain catastrophizing scale (PCS) questionnaire
- Where
- Nepal
- Volunteers
- 135 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Knee Injuries, Pain Syndrome
The Effect of Kinesio Taping® on Motor Control in Patients With Patellofemoral Pain Syndrome
Background: Recently, several professionals are using the Kinesio Taping® in the treatment of pathologies related to the knee, aiming to improve the motor control, increase the response of muscle activation and promoting better…
- Trial name
- NCT03117205
- Testing
- Application of Kinesio Taping®
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo