Clinical trials: Lower Extremity Pain
Flexible Flatfoot
The Effect of Customized Insoles on Biomechanics and Pain in Patients With Functional Flatfoot
The aim of present study is to compare the effects of 3D printing customized insoles using different thermoplastic materials on functional flatfoot patients' foot function and biomechanics
- Trial name
- NCT04381039
- Testing
- Insole
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Injuries, Injury Arm
Virtual Reality for Pain in Acute Orthopedic Injuries
The goal of this study is to pilot test a skills-based virtual reality (VR) for acute orthopedic injury. It will measure the feasibility, signals of improvement, exploratory pain mechanisms, and user experience of an established…
- Conditions
- Injuries, Injury Arm, Injury;Sports, Injury, Knee
- Trial name
- NCT05552430
- Testing
- RelieveVRx
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Ankle Fracture, Rehabilitation
Bracing After Ankle Fracture
Ankle fractures are common, debilitating and usually treated with immobilisation using a foot-ankle brace (walker). Emerging evidence suggests that a less restrictive brace may reduce recovery time without increasing the risk of…
- Conditions
- Ankle Fracture, Rehabilitation, Recovery
- Trial name
- BAF (NCT07163091)
- Testing
- ankel stirrup, Foot-ankel brace (walker)
- Where
- 16 sites in Denmark, Faroe Islands
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Osteoarthritis, Spinal Diseases
The Effect of AposTherapy on the Level of Pain, Function and Quality of Life in Patients With Neuro-muscular and Neurological Disorders
The purpose of the study is to examine the effect of a new biomechanical device and treatment methodology (AposTherapy) on gait patterns, pain, function and quality of life of patients with musculoskeletal and neurological…
- Conditions
- Osteoarthritis, Spinal Diseases, Ligament Rupture, Lower Extremity Fracture
- Trial name
- NCT01266382
- Testing
- AposTherapy
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Back Pain, Chronic Pain
Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode
The primary objective of this study is to evaluate the acute and chronic efficacy of spinal cord stimulation using the Precision implantable neurostimulation device with the Artisan paddle electrode in patients with Failed Back…
- Conditions
- Back Pain, Chronic Pain, Pain in Leg, Unspecified
- Trial name
- NCT00386724
- Testing
- Precision Spinal Cord Stimulation System, Artisan Surgical Lead
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Boston Scientific Corporation
Chronic Pain, Low Back Pain
A Prospective, Multi-site, Randomized, Sham-Controlled, Double-Blind Trial With One-Way Crossover Designed to Assess the Effectiveness and Safety of the Gimer NeuroBlock SCS Trialing System for the Treatment of Chronic Back Pain and/or Lower Limb Pain
This study is a prospective, multi-site, randomized, shamcontrolled, double-blind trial with one-way crossover designed to assess the effectiveness and safety of the Gimer NeuroBlock SCS Trialing System for the treatment of…
- Conditions
- Chronic Pain, Low Back Pain, Lower Limb Pain
- Trial name
- NCT04693650
- Testing
- NeuroBlock UHF stimulation
- Where
- 4 sites in Taiwan
- Volunteers
- 22 people
- Sponsor
- GiMer Medical
Neck Pain, Ankle Injuries
Acupuncture for Pain Control in the Emergency Department
Acupuncture is widely used for managing acute and chronic pain conditions. In the context of an emergency department (ED), patients often present with non-emergent acute pain symptoms.
- Conditions
- Neck Pain, Ankle Injuries, Headache Disorders, Primary
- Trial name
- NCT02013908
- Testing
- Acupuncture plus standard ED management, Standard ED management alone
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Peripheral Arterial Disease, Claudication
Comparative Effectiveness Research Study of Peripheral Arterial Disease (PAD)
The specific aim of this study is to prospectively compare outcomes (functional, quality of life, risk-adjusted clinical event) of medical management, surgical or endovascular (angioplasty or stent placement) interventions for…
- Trial name
- NCT01378260
- Where
- 12 sites in United States
- Volunteers
- 323 people
- Sponsor
- University of Washington
Lumbar Degenerative Disease, Lumbar Radiculopathy
Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation
The goal of this clinical trial is to compare the clinical effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in patients aged 18-85 with single-level lumbar disc herniation who have not undergone…
- Conditions
- Lumbar Degenerative Disease, Lumbar Radiculopathy, Sciatic Leg Pain, Sciatic Nerve Compression
- Trial name
- NCT06615518
- Testing
- FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- University of Opole
Degenerative Disc Disease, Spine Fusion
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
This is a phase IV post-marketing study for MagnetOs Flex Matrix. MagnetOs Flex Matrix is a synthetic bone graft extender product that is routinely used by surgeons as a treatment for patients with degenerative disc disease and…
- Conditions
- Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
- Trial name
- PRECISE (NCT05037968)
- Testing
- MagnetOs Flex Matrix, Trinity Elite
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kuros Biosurgery AG
Osteoarthritis, Knee
Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Knee osteoarthritis has been ranked 11th highest contributor to non-fatal burdens in the world. Many research studies have discussed the relationship of hip muscle with knee joint stating that impaired hip strength can be a…
- Trial name
- NCT04769531
- Testing
- Hip Joint Mobilizations, Hip joint Muscle strength training, knee strengthening and flexibility exercises
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Dow University of Health Sciences
Chronic Back Pain, Chronic Back and Leg Pain
High Frequency PNS Stimulation Study for Back and Leg Pain
Prospective, double blinded, randomized, clinical study investigating the effects of high frequency PNS for the treatment of chronic back or back and leg pain.
- Trial name
- NCT03312010
- Testing
- PNS HF
- Where
- 2 sites in Belgium
- Volunteers
- 38 people
- Sponsor
- Curonix LLC
Manual Therapy, Myofascial Pain Syndrome
Plantar Pressures After Pressure Release of the Flexor Digitorum Brevis Muscle Versus a Non-emission Laser.
In this study we will test the effects of pressure release on the Flexor digitorum brevis muscle on the plantar pressures variables using a pressure platform.
- Conditions
- Manual Therapy, Myofascial Pain Syndrome, Foot, Flat Foot
- Trial name
- NCT06499545
- Testing
- Pressure release, Non emision Laser
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Hip Fracture Surgeries
Dexamethasone + Intrathecal Morphine in Hip Fractures
Hip fractures (proximal femur fractures) are a global public health problem with high morbidity and mortality rates, especially in the geriatric population aged 65 years and older.
- Trial name
- NCT07037745
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Phantom Limb Pain
Pre-emptive Sciatic Bloc to Prevent Lower Limb Phantom Pain
Phantom limb pain is a complication of amputation. Although pre-empitve epidural analgesia was once thought to prevent such a com plication, recent studies did not demonstrate this.
- Trial name
- NCT00528463
- Testing
- sciatic nerve block
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Université de Sherbrooke
Osteoarthritis, Knee, Obesity
Effects of Diet Control and Resistance Exercise Training on Obesity Adults With Knee Osteoarthritis
The purpose of this study was to investigate the effects of obesity on knee degenerative arthritis on body composition after dietary control and elastic resistance exercise; and whether persistent exercise habits and dietary…
- Conditions
- Osteoarthritis, Knee, Obesity, Diet, Healthy, Training Group, Sensitivity
- Trial name
- NCT03973463
- Testing
- Elastic knee joint movement
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Pain, Acute
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities.
- Trial name
- NCT06411197
- Testing
- Hypertonic saline injection, Isotonic saline injection
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen