Clinical trials: Lower Extremity Pain
Non-specific Pain in Lower Extremities
Insoles Effect on Pain and Daily Activities
The aims of this study were to evaluate the effects of insoles on pain, daily activities and physical activity level, and to investigate the relation between satisfaction with the insoles and their actual use in individuals with…
- Trial name
- NCT01640899
- Testing
- Shoe Insoles
- Where
- Sweden
- Volunteers
- 89 people
- Sponsor
- Centre for Rehabilitation Research, Örebro
Electromyography, Knee Injuries
Vastus Medialis Activation During McMurray's Test
This study will use electromyography to evaluate activation patterns of the vastus medialis and vastus lateralis muscles during the McMurray's knee examination test in different knee positions.
- Conditions
- Electromyography, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT05965804
- Testing
- McMurray knee examination test
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Plantar Fasciitis
Effect of Kinesio Taping and Extracorporeal Shock Wave Therapy on Plantar Fasciitis
Type of this study: Prospective randomized controlled study. Purpose: The aim of this study is to compare the acute effect of pain level, lower extremity functionality level and plantar fascia flexibility in patients with plantar…
- Trial name
- NCT06055933
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Necmettin Erbakan University
Patellofemoral Pain Syndrome, Exertional Lower Leg Pain
Prevention of Injuries by an Exercise Program - a RCT
Overuse injuries are a major concern for physical active individuals. Study hypothesis is that an exercise programme based on known intrinsic risk factors can prevent overuse injuries in soldiers undergoing basic military…
- Trial name
- NCT00348647
- Testing
- physical training program to prevent injuries
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Childhood Obesity
Biofeedback Gait Retraining to Reduce Lower Extremity Impact in Obese Children
The purpose of the study is to explore if self biofeedback program can reduce ground reaction force (GRF) from the lower extremity of the body and in the knee in particular and help obese children to avoid knee injuries.
- Trial name
- NCT02580825
- Testing
- Biofeedback gait retraining, Exercise
- Where
- Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Sprains and Strains, Pain
A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament
The purpose of this study is to explore the pain-relieving effects and safety of two analgesic treatment regimens as compared to placebo in patients experiencing acute musculoskeletal pain.
- Trial name
- NCT00236535
- Volunteers
- 603 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain, Postoperative, Anterior Cruciate Ligament Injury
Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions
Nerve blocks are used to provide pain control after moderately painful orthopedic surgeries. Anterior Cruciate Ligament (ACL) reconstruction with patellar autograft is a painful orthopedic procedure performed after traumatic…
- Trial name
- NCT03208478
- Testing
- Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Pain Threshold, Myofascial Trigger Point
Comparative Effects of Myofascial Induction Therapy Versus Gastrocnemius Pressure Release Treatment on Trigger Point Pressure Pain Threshold in Proximal Muscles and Ankle Range of Motion.
The aim of the study is to test the effect of myofascial induction and pre-pressure release of the grastrocnemius muscle on the proximal musculature: biceps femoris, flexor digitorum brevis and extensor digitorum grandus on the…
- Conditions
- Pain Threshold, Myofascial Trigger Point, Manual Therapy, Range of Motion
- Trial name
- NCT06499441
- Testing
- Myofascial induction in gastrocnemius, Preassure release
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Low Back Pain
Effect of Hamstring Stretching and Neural Mobilization on Range of Motion and Low Back Pain
This study was designed to answer 3 primary research questions: 1. In adults with low back pain, reduced SLR ROM (Range of Motion) and a positive sensitized SLR (Straight leg raise) test, does neurodynamic mobilization result in…
- Trial name
- NCT01483573
- Testing
- neural mobilization, straight leg raise
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Knee Pain Chronic, Knee Injuries
Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Non-steroidal anti-inflammatory medication (NSAID) therapy is a mainstay treatment for joint pain and painful musculoskeletal disorders.
- Trial name
- NCT02068859
- Testing
- Diclofenac Cream 8%, Diclofenac Gel 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- FPR Specialty Pharmacy
Sprains and Strains, Pain
A Safety and Effectiveness Study of Acetaminophen Extended Release (3900 mg/Day) and Ibuprofen (1200 mg/Day) in the Treatment of Pain Associated With Ankle Sprains.
The purpose of this study is to compare the safety and effectiveness of 1300 mg acetaminophen extended release given three times daily for nine days to that of 400 mg ibuprofen given three times daily for nine days for the signs…
- Trial name
- NCT00261560
- Testing
- acetaminophen
- Volunteers
- 260 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Familial Mediterranean Fever
Magnetic Resonance (MR) Spectroscopy In Familial Mediterranean Fever (FMF) Patients
Familial Mediterranean fever (FMF) is an inherited disorder of unknown etiology, characterized by recurrent episodes of fever, peritonitis and/or pleuritis.
- Trial name
- NCT00658060
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Failed Back Surgery Syndrome
Efficacy Study of the Octapolar Lead in Patients With Failed Back Surgery Syndrome (FBSS) With Chronic Pain
Spinal cord stimulation (SCS) has been used for over 40 years to treat neuropathic pain. Various clinical studies have shown a beneficial effect of SCS on pain in patients with Failed Back Surgery Syndrome (FBSS).
- Trial name
- NCT01096147
- Testing
- Spinal cord stimulation with eight polar electrode
- Where
- 8 sites in Belgium, Norway and 1 more
- Volunteers
- 80 people
- Sponsor
- Rik Buschman, PhD
Chronic Pain of Left Foot (Finding), Chronic Pain of Right Foot (Finding)
Gait Analysis Using OneStep Smartphone Application
OneStep technology is a smartphone application, utilizing smartphone sensors to provide ongoing gait diagnostics. In this longitudinal study, 50 consecutive patients with lower-extremity disability or chronic pain, will be using…
- Trial name
- NCT05012891
- Testing
- OneStep Smartphone Application
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Reuth Rehabilitation Hospital
Anterior Cruciate Ligament Injuries
A Study Of Focused Shockwave For Anterior Knee Pain Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to investigate whether Focused Shockwave (FSW) therapy reduces anterior knee pain following anterior cruciate ligament reconstruction (ACL-R) with bone-patellar tendon-bone (BTB) or quadriceps tendon…
- Trial name
- NCT07580157
- Testing
- Focused Shockwave
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Injury, Postoperative Pain
Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction
The study aims to investigate the effect of the popliteal plexus block (PPB) on postoperative pain in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT03130049
- Testing
- Popliteal plexus block
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Plantar Fasciitis
Effectiveness of Kinesiotaping as Compared to Lower Extremity Stretching on Pain and Disability in Patients With Plantar Fasciitis
Plantar fasciitis is described as a chronic degenerative process at the origin of the strong, fibrous band running at the bottom of feet connecting bones of heel to toes and supporting arch of feet known as plantar fascia and…
- Trial name
- NCT07820202
- Testing
- Kinesiotaping intervention, Lower limb stretching exercises
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Health Education Research Foundation (HERF)
Closed Multiple Fractures of Upper and Lower Limbs
Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine
the investigators assessed the effects of low-dose IV ketamine-midazolam versus morphine on pain control in trauma patients with closed limb fracture(s); and also compared the incidence of adverse events (mainly cardio pulmonary…
- Trial name
- NCT01807429
- Testing
- Ketamine-midazolam, Morphine
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences