Clinical trials: Lower Leg Edema
Edema Leg
Breaking of Sitting Time Prevents Lower Leg Swelling
Sitting or standing during a prolonged and uninterrupted period of time is related to negative health outcomes, such as lower extremity swelling.
- Trial name
- Break_sitting (NCT05173558)
- Testing
- Uninterrupted motionless standing, Uninterrupted motionless sitting, Sit-to-stand transitions
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Edema
Oedematous Lower Limb Subcutaneous Drainage in Palliative Care
Background : Edema of lower extremities is a concern ranging from 19 % to 60% of palliative cancer patients. Lymphedema decreases mobility, induces pain, impacts daily activities, esthetic and behavior.
- Trial name
- DSOPAL (NCT02473744)
- Testing
- subcutaneous drainage
- Where
- 7 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Limoges
Edema Leg
Cross Therapy Registry - Edema - US
The geko™ Cross Therapy Registry - Edema (gekoTM CTR - Edema) study will prospectively and systematically collect clinical data on all device variants used in standard care pathways for edema management allowing for the…
- Trial name
- CTR-Edema-US (NCT04700735)
- Testing
- geko Neuromuscular Electro Stimulator (NMES)
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Firstkind Ltd
ACL Injury, Pain
Effect of Biophysical Stimulation on Intraspongious Bone Edema in Anterior Cruciate Ligament Reconstruction
The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate…
- Conditions
- ACL Injury, Pain, Magnetic Field Exposure
- Trial name
- NCT04255407
- Testing
- I-ONE® therapy, Anti-inflammatory drug
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Ortopedico Rizzoli
Venous Insufficiency of Leg, Venous Reflux
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
The purpose of this study is to evaluate the effectiveness of Vasculera in reducing post procedural pain, bruising and edema in the post procedure period for patients diagnosed with C2-C5 disease requiring an intervention(s).
- Conditions
- Venous Insufficiency of Leg, Venous Reflux, Varicose Veins, Lower Extremity Edema Chronic
- Trial name
- NCT02936271
- Testing
- Vasculera
- Where
- United States
- Sponsor
- Corewell Health West
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Kidney Transplant, Kidney Pancreas Transplant
The Effect of Neuromuscular Stimulation on Post-Transplant Leg Edema
This will be a randomized, controlled trial involving kidney and kidney pancreas transplant patients. There will be 2 groups and patients that will be randomized to one of the two groups.
- Conditions
- Kidney Transplant, Kidney Pancreas Transplant, Edema
- Trial name
- NCT01860820
- Testing
- Geko device
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Venous Insufficiency
Non-Invasive Management of Chronic Venous Insufficiency
The purpose of this study is: -item one to use two new non-invasive technologies to evaluate scarring and swelling associated with chronic venous insufficiency.
- Trial name
- NCT00950378
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Leg Edema, Venous; Return (Anomaly)
Elevate to Alleviate Evidence Based Study
Venous return in the circulatory system of lower limbs results from the interaction of several mechanisms, and reflects the balance between blood inflow and outflow.
- Conditions
- Leg Edema, Venous; Return (Anomaly), Leg Elevation
- Trial name
- ETA (NCT04514939)
- Testing
- Elevation of the legs during bed rest
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Catanzaro
Edema Leg
A New Intelligent Stocking for Quantification of Edema in the Lower Limbs
The purpose of the study is to evaluate a prototype of an intelligent stocking (Edema Stocking Device [ESD]), consisting of two stretch sensitive sensors, as a new method for continuously lower leg volume monitoring.
- Trial name
- NCT05310435
- Testing
- Single volume measurement with ESD, Single volume measurement with WDV, Single circumference measurement with tape measure
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Compresion Therapy, Post-operative Edema
Post-operative Complication, Impulsive Compression, in Situ Bypass
To investigate whether compression therapy with foot pump reduce post-operative edema, facilitate wound healing of operation wounds, promote healing of ischemic ulcers and shorten hospitalization, increase and improve the…
- Conditions
- Compresion Therapy, Post-operative Edema, Wound Complication, Ischemia Limb
- Trial name
- 50506 (NCT03192982)
- Testing
- A-V impulse 6000 Series, Standard treatment (compression)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Kolding Sygehus
Edema Leg, Pain
Does Edema Affect the Adjustment of TENS Amplitude
The goal of this pre-post clinical trial is to compare the amplitude settings of three different frequency TENS modes (Conventional TENS, LF TENS, HF TENS) in patients who had undergone total knee arthroplasty, both with the…
- Trial name
- NCT06153277
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Karamanoğlu Mehmetbey University
Lower Extremity Swelling, Lower Extremity Edema
Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema
The present study aims to use a game-based tele-exercise program for patients using a compression garment to improve lower extremity edema.
- Conditions
- Lower Extremity Swelling, Lower Extremity Edema, Venous Insufficiency of Leg
- Trial name
- NCT05520008
- Testing
- Game-based exercise
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Gynecologic Cancer
Randomized Trial of Exercise on Lower Extremity Edema After Lymphadenectomy in Gynecologic Cancer
The primary outcome is the change in lower extremity edema-related symptoms. Secondary outcomes include the compliance rate of management guidelines for lower extremity edema, the performance rate for pelvic and lower extremity…
- Trial name
- NCT01849224
- Testing
- Pelvic and lower extremity exercise
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- National Cancer Center, Korea
Patients With Lower Extremity Venous Ulcers, Patients With Localized Edema
Proof-of-concept Study for Bioimpedance Based Monitoring of Venous Ulcers During Galvanic Stimulation
The research group will choose no more than 10 patients having a lower extremity venous ulcer(s), less than 5cm diameter and with an estimated one month time of re-epithelization.
- Trial name
- NCT02101645
- Testing
- Periodical low intensity direct current (LIDC) stimulation of wound., Compression therapy of swollen limbs.
- Where
- Finland
- Volunteers
- 6 people
- Sponsor
- Tampere University Hospital
Ankle Sprains, Ankle Injuries
Diagnostic Ultrasonography in Physiotherapy
Ankle injuries are among the most common traumatological injuries of the lower limb accounting for approximately 50% of all sports injuries and 25% of musculoskeletal injuries in general.
- Conditions
- Ankle Sprains, Ankle Injuries, Ankle Edema, Ankle Impingement
- Trial name
- SonograPHY (NCT05916300)
- Testing
- Diagnostic ultrasonography-guided physiotherapy group
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- Petr Routner
Oedema
Does NMES Help Relieve Lower Limb Oedema and Improve Joint Mobility and Skin Tissue Oxygenation Levels?
Neuromuscular Electrical Stimulation (NMES) will be facilitated through the use of a stimulator, with the patient in a semi recumbent position, using UltraStim electrodes.
- Trial name
- NCT01936155
- Testing
- Custom-built, two-channel stimulator
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Lymphedema
Lymphedema Study for Arm or Leg Lymphedema
This study compares the effectiveness of a study drug versus placebo in the treatment of lymphedema.
- Trial name
- NCT02257970
- Testing
- Ketoprofen
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Stanford University
Right Heart Failure, Cor Pulmonale
Effect of Normatec Pump for Relief of Leg Edema in Patients With Right Heart Failure
Mobilization of fluid from the legs with the Normatec pump in patients with right heart failure, may empty the "reservoir" in the legs from excessive fluid, enabling fluid overload to collect there rather than in the liver or in…
- Trial name
- NCT00834145
- Testing
- A mechanical compression pump
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center