Clinical trials: Lower Limb Deformities
Osteoarthritis, Avascular Necrosis
Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and clinical outcome data on the Hyperion® system in primary and…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Functional Deformities
- Trial name
- NCT03382665
- Where
- 3 sites in Germany
- Volunteers
- 70 people
- Sponsor
- Zimmer Biomet
Clubfoot
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle
Rate Of Residual Clubfoot Deformity With Correlation To Absence Of Peroneus Tertius Muscle , A Prospective Study.
- Trial name
- NCT03749265
- Testing
- Ultrasound test
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Anterior Cruciate Ligament Injuries, Hallux Rigidus
Collagen for Treatment of Musculoskeletal Injuries
The purpose of the study: Evaluation of the clinical efficacy and safety of the use of collagen matrix/membrane in the surgical treatment of the consequences of injuries and diseases of the musculoskeletal system (anterior…
- Trial name
- NCT06331741
- Testing
- Anterior cruciate ligament reconstruction, using graft, augmented with collagen membrane, Anterior cruciate ligament reconstruction, using graft, not augmented with collagen membrane (control group), Resection arthroplasty of the first metatarsophalangeal joint with the introduction of a collagen membrane into the joint cavity
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Flat Foot, Lateral Column Lengthening
Evaluation of the Titan 3-D™ Wedge System
Evaluate clinical healing and radiographic maintenance of correction following an LCL procedure or medial cuneiform osteotomy (Cotton) at 6 months following the use of the TITAN 3-D™ Wedge.
- Conditions
- Flat Foot, Lateral Column Lengthening, Medial Cuneiform Osteotomy
- Trial name
- NCT03421665
- Testing
- Titan 3D Wedge System
- Sponsor
- Paragon 28
Plantar Fascitis
Effects Of Navicular Mobilization In Patients With Planter Fasciitis
The significance of studying the effects of navicular mobilization in patients suffering from plantar fasciitis lies in its potential to provide valuable insights into non-invasive treatment approaches for a common and…
- Trial name
- NCT06377800
- Testing
- navicular mobilization along conventional therapy., conventional therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Club Foot
Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club Foot
Club foot (congenital talipes equinovarus) is a common birth deformity affecting 1-2 per 1,000 live births, with even higher rates in low-income countries.
- Trial name
- NCT07554092
- Testing
- Ponseti Casting, Accelerated Ponseti Casting
- Where
- Pakistan
- Volunteers
- 144 people
- Sponsor
- Khyber Medical University Peshawar
Deformity; Skin, Fat Redistribution
Safety and Efficacy of Deoxycholate Treatment of Small Fatty Deformities ( SFD)
The purpose of this study is to evaluate the efficacy and safety of deoxycholate for the treatment of lipocytic ("fatty") deformities of the trunk and lower extremities; this includes areas such as cellulite or body contour…
- Conditions
- Deformity; Skin, Fat Redistribution, Lipodystrophy
- Trial name
- SFD (NCT07880301)
- Testing
- Kybella
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- The Maas Clinic
Clubfoot
Children Born With Club Feet
Clubfoot is one of the most common birth defects, with a prevalence in Europe estimated between 1 and 4.5 for 1000 live birth. It is useful to distinguish the forms of isolated clubfoot, and the forms related to others…
- Trial name
- CBCF (NCT03671863)
- Testing
- Invasive analysis (caryotype, CGH array), Prenatal management
- Where
- France
- Volunteers
- 219 people
- Sponsor
- University Hospital, Montpellier
Pes Planus
Low Dye Taping Technique and Temporary Felt Insoles on Pain and Disability in Children With Pes Planus.
This study aims to determine comparative effects of low dye taping technique and temporary felt insoles on pain and disability in children with pes planus.
- Trial name
- NCT05764967
- Testing
- Low Dye Taping, Temporary Felt Insoles
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Diabetic Neuropathies, Distal Peripheral Sensory Neuropathy
Diabetic Neuropathy Screening Study 1.1 + Substudy 1.2-1.3-1.4
The overall objective of this project is to describe the prevalence of and risk factors to diabetic neuropathy in a representative cohort of diabetes patients and to investigate pathophysiological conditions in those patients…
- Conditions
- Diabetic Neuropathies, Distal Peripheral Sensory Neuropathy, Diabetic Foot, Foot Deformities
- Trial name
- DANES (NCT05043636)
- Testing
- Vagus, HeartsTrends, Sudoscan
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Clubfoot
Ultrasound Assessment of Achilles Tendon-Neurovascular Distance in Infants With Unilateral Clubfoot
This study aims to assess the distance between the Achilles tendon and nearby neurovascular bundles bilaterally in infants with unilateral clubfoot deformity using ultrasound (US)- Doppler at 1 cm and 2 cm above the calcaneal…
- Trial name
- NCT07473908
- Testing
- ultrasound
- Volunteers
- 40 people
- Sponsor
- Assiut University
Chronic Limb-threatening Ischemia, Microtia
the Gut Microbiome and Metabolomics in Chronic Lower extreMities Threatening Ischemia
Intestinal floras and their metabolites are involved in progressing metabolic and cardiovascular diseases. However, currently, articles related to the relationship between intestinal floras and atherosclerosis mainly focus on…
- Trial name
- MMM (NCT06220994)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Congenital Talipes Equinovarus
Management of Congenital Talipes Equinovarus by Saleem's Protocol
The main objective of this study is to evaluate the effectiveness of Saleem's protocol treatment plan for congenital ideopathic talipes equino varus deformity using early tenotomy and serial foot casting.
- Trial name
- NCT05957627
- Testing
- Saleem's protocol
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Pakistan Society for Rehabilitation of Differently Abled Hospital
Hallux Limitus
Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial
To determine the efficacy of Metatarsal Dynasplint Sytem (MTP) in reducing contracture of hallux limitus secondary to Bunionectomy, in a longitudinal, controlled trial.
- Trial name
- Bunionectomy (NCT01589679)
- Testing
- standard of care, Metarsal Dynasplint
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Dynasplint Systems, Inc.
Pain
Examination and Treatment of Pain in Front Foot
Tibial flat foot deformity is the most common reason for metatarsalgia. Flat foot deformity is a sign of degenerated problems such as weakness in ligament or fractures.
- Trial name
- NCT01590186
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Leg Length Discrepancy, Varus/Valgus Deformities of the Knee
Retrospective Eight Plate Study
Understanding bone growth and achieving bone deformity corrections re-mains one of the oldest challenges in paediatric orthopaedics.
- Trial name
- NCT01625975
- Where
- 7 sites in Germany, India and 2 more
- Volunteers
- 138 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Cerebral Palsy, Pes Planus
Outcomes of the Evans Calcaneal Lengthening Based on Bone Grafting Material
The Evans calcaneal lengthening is a common surgical correction used for children with spastic cerebral palsy (CP) and painful flat feet. This procedure involves the insertion of a trapezoidal bone graft into the calcaneus bone.
- Trial name
- NCT02075853
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Idiopathic Clubfoot (Talipes Equinovarus)
Efficacy of Botox in Patients With Idiopathic Clubfoot
The purpose of this study was to determine the efficacy of adding Botox injection to serial manipulations and castings in patients with clubfoot.
- Trial name
- NCT00152334
- Testing
- Botox
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of British Columbia
Flat Foot; Rigid, Flat Foot; Spastic
Joint Preserving Surgery for Correction of Spasmodic Flat- Foot in Skeletally Mature Foot
the investigators want to obtain a functional and radiological outcome of peroneus brevis, tertius and extensor digitorum longus muscles lengthening together with calcaneal osteotomies in the treatment of the spasmodic flat- foot.
- Trial name
- NCT03880318
- Testing
- Joint Preserving Surgery in spasmodic flat foot
- Volunteers
- 22 people
- Sponsor
- Assiut University
Behcet Disease, Behcet Disease and Vascular Involvement
Immunosuppressive Therapy Alone Versus Plus Oral Anticoagulation in the Treatment of VT Associated With Behcet's Disease
This study is a Phase III, multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial investigating the treatment of lower extremity venous thrombosis associated with Behçet's Disease.
- Conditions
- Behcet Disease, Behcet Disease and Vascular Involvement, Deep Venous Thromboses, Post Thrombotic Syndrome
- Trial name
- BETTER (NCT06925698)
- Testing
- Rivaroxaban plus immunosupression
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University