Clinical trials: Lower Limb Deformity, open to volunteers
Pes Planus
The Effect of Orthosis and Exercise in Pes Planus
There is no definite evidence for the conservative treatment of pes planus. We want to verify the combination efficacy of orthosis and toe walking exercise for the treatment of pes planus.
- Trial name
- NCT03494374
- Testing
- UCBL orthosis
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Ju Seok Ryu
Flat Feet, Flexor Tendon Rupture
Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw
The goal of this observational study is to compare the use of a screw made of human bone (Shark-Screw®, Surgebright-GmbH) with the metal/Bio-Tenodesis screw (Arthrex) in the treatment of the symptomatic flatfoot using the…
- Conditions
- Flat Feet, Flexor Tendon Rupture, Tibialis Posterior Dysfunction, Deformity, Foot
- Trial name
- NCT05643079
- Testing
- medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with metal/Bio-Tenodesis screws, medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with Shark Screws®
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Orthopedic Hospital Vienna Speising
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Flexible Flatfoot
Early Warning and Intervention Mechanism of Foot Health Risk in Children and Adolescents
This clinical study was a prospective intervention study. The growth and development parameters and kinematic parameters of 120 children were planned to be collected for an observational study, and then the sensors were used to…
- Trial name
- NCT06581978
- Testing
- Whole-Body Vibration Intervention, Exercise Intervention Group
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Hallux Valgus Deformity
A Study on the Biomechanical Mechanisms of Orthotic/Physical Training Correction of Hallux Valgus and Its Impact on the Lower Limbs
The study population of this project is mainly young people. Our goal is to investigate the kinematic and kinetic characterization brought about by different conservative treatment modalities for hallux valgus.
- Trial name
- NCT07036120
- Testing
- orthosis, foot exercises
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wan Xinzhu
Patellofemoral Pain Syndrome
Effects of Agility Training With and Without Foot Mobilization In Patellofemoral Pain Syndrome.
Patellofemoral pain syndrome (PFPS) is referred to as peripatellar or retro-patellar pain, which is characterized by alterations in the physical and biomechanical features of the patellofemoral joint.
- Trial name
- NCT06674707
- Testing
- Agility Training with Foot mobilization., Agility Training without Foot mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Flat Foot; Spastic
To Evaluate the Efficiency and Results of Adding BFR to the Physical Therapy Program fo Managing Adolescents Presented With Spasmotic Flatfoot Deformities Compared to the Standard Physical Therapy Program Without BFR
The goal of this randomized clinical trial is to evaluate the efficiency and results of adding blood flow restriction (BFR) training to the physical therapy program for managing adolescents presented with spasmotic flatfoot…
- Trial name
- BFR SFFD (NCT07343752)
- Testing
- blood flow restriction
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Equinus Contracture
A Needle Technique for Achilles Tendon Lengthening in Pediatric Patients: A Prospective Study on Efficacy, Safety, and Feasibility
For years, we have used a minimally invasive and biological variant of Achilles tendon lengthening using a needle inserted into the Achilles tendon so that it is weakened and can be gradually stretched to the desired length.
- Trial name
- NCT06912061
- Testing
- Needle tendon lengthening technique
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Vestre Viken Hospital Trust
Foot Deformities, Flatfoot
Translation, Cross-cultural Adaptation, and Validation of the FPI-6 in Spain
The objective of this study is to translate, cross-culturally adapt, and validate the Spanish version of the Foot Posture Index (FPI-6).
- Trial name
- FPI-6-ES (NCT07590297)
- Testing
- Spanish version of the Foot Posture Index (FPI-6)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paloma López Ros
Cystic Fibrosis (CF)
Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis
This research aims to evaluate the effects of upper and lower limb exercises on muscle strength and pulmonary function in children diagnosed with CF.
- Trial name
- NCT07508904
- Testing
- Arm Cycle Ergometry, Leg Cycle Ergometry
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Deformity of Limb
Study of Infantile Lower Limb Malformations and Deformities
The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure.
- Trial name
- REMEDIA-I (NCT06519175)
- Testing
- Conservative treatment, Single or multi-stage surgery, Amputation
- Where
- 7 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Ortopedico Rizzoli
Stroke, Equinovarus Foot
Evaluation of Percutaneous Cryoneurotomy Compared to Surgical Open Neurotomy for the Management of Equinovarus Foot Deformity in Patients With Refractory Lower Limb Spasticity After Stroke
CRYOSTROKE study is designed : to compare the efficacy and safety of percutaneous CryoNeurotomie (CN) versus surgical neurotomy (SN) on spasticity, 90 days after intervention, in post-stroke patients presenting with spastic…
- Conditions
- Stroke, Equinovarus Foot, Refractory Lower Limb Spasticity
- Trial name
- CRYOSTROKE (NCT06726434)
- Testing
- Surgical neurotomy (SN), Cryoneurotomy (CN)
- Where
- 7 sites in France
- Volunteers
- 114 people
- Sponsor
- Poitiers University Hospital
Cavus Foot
Clinical Examination of Cavovarus Feet
Cavovarus feet are complex deformities in multiple planes. There is little consensus on the best way to address deformities. Furthermore there are various different phenotypes and we have previously described 4 distinct forefoot…
- Trial name
- NCT07644078
- Testing
- Clinical Examination
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Behcet Disease, Behcet Disease and Vascular Involvement
Immunosuppressive Therapy Alone Versus Plus Oral Anticoagulation in the Treatment of VT Associated With Behcet's Disease
This study is a Phase III, multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial investigating the treatment of lower extremity venous thrombosis associated with Behçet's Disease.
- Conditions
- Behcet Disease, Behcet Disease and Vascular Involvement, Deep Venous Thromboses, Post Thrombotic Syndrome
- Trial name
- BETTER (NCT06925698)
- Testing
- Rivaroxaban plus immunosupression
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University
Flat Foot
Oblique K-wire Control in Calcaneal Osteotomy for Flatfoot Correction
Adult-acquired flatfoot deformity (AAFD) often requires surgical correction when conservative methods fail. Calcaneal displacement osteotomy is a key procedure in restoring alignment.
- Trial name
- NCT06957353
- Testing
- oblique K-wire technique in controlling Calcaneal displacement during osteotomy in flatfoot correction
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Pes Planus, Running Related Injuries
Comparing Effects of Custom Foot Orthotic Intervention to Foot-Core Training Protocol on Lower Extremity Kinematics in Runners With Pes Planus
Running is a full body movement that requires the feet to support the body and absorb forces greater than the individual's body weight in a repeated fashion.
- Trial name
- CFO (NCT07723573)
- Testing
- Custom foot orthoses, Intrinsic foot muscle strengthening exercises
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Pes Planus
Effects of Custom 3D Printed Insoles and Short Foot Exercises in Pes Planus
The primary purpose of this study is to evaluate the effects of combining custom 3D-printed medial arch-supported insoles with short foot exercises on foot posture, balance, and gait parameters in individuals with pes planus…
- Trial name
- NCT07895602
- Testing
- Custom 3D Printed Insoles and Short Foot Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kutahya Health Sciences University
Club Foot
Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting
The purpose of this study is to assess if the application of Mastisol, a liquid adhesive, improves outcomes during bilateral clubfoot casting and reduces complications and development of complex clubfoot for the duration of their…
- Trial name
- NCT07154550
- Testing
- Mastisol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Diabetic Peripheral Neuropathy, Entrapment Neuropathy
Ultrasound-Guided Nerve Hydrodissection for Diabetic Lower Limb Entrapment Neuropathy
The goal of this clinical trial is to learn if a single session of ultrasound-guided nerve hydrodissection can relieve symptoms of diabetic lower limb entrapment neuropathy, a condition caused by compressed nerves in the leg that…
- Trial name
- HUND (NCT07625020)
- Testing
- Ultrasound-guided nerve hydrodissection treatment
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Chongqing Medical University