Clinical trials: Lower Limb Trauma
Lower Limb Amputation Below Knee (Injury)
Auto Control of Volume Management for Limb Loss
The aim of this research is to create a prosthetic system that will automatically adjust the fit of the socket and create a well-fitting prosthesis for people with leg amputations who experience volume fluctuations when using…
- Trial name
- NCT03550118
- Testing
- Adjustable socket
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Washington
Tranexamic Acid, Trauma
Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery
This study was done to evaluate the efficacy of Tranexamic Acid (TXA) in reducing blood transfusion requirement in patients of lower limb trauma undergoing surgery.
- Conditions
- Tranexamic Acid, Trauma, Lower Extremity Fracture
- Trial name
- NCT04986813
- Testing
- Tranexamic acid injection, Normal Saline
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Jaspreet Singh
Leg Injuries, Winter Sport Resorts
Evaluation of the Prevention of Thromboembolic Disease in Patients With a Lower Limb Trauma, Non Surgical, in Winter Sports Resort
The purpose of this study is to evaluate the impact of thromboembolic diseases and heparin complications in patients with a lower limb trauma supported by physicians of mountain.
- Conditions
- Leg Injuries, Winter Sport Resorts, Outpatients
- Trial name
- M2M-Thrombose (NCT01303523)
- Where
- 28 sites in France
- Volunteers
- 1,627 people
- Sponsor
- Floralis
Diabetic Foot, Diabetic Foot Ulcer
Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers
People with diabetes often experience foot ulcers, which can harm their ability to move, lower their quality of life, and increase the chances of losing a limb.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Foot Wound
- Trial name
- NCT06487780
- Testing
- Lifestyle-focused Occupational Therapy Intervention, Education
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Ankle Sprain 1St Degree
First-degree Ankle Sprains
Grade I ankle sprains are common, especially among athletes, women, teenagers, and physically active individuals. While over a million cases are reported annually, this represents only half of the total occurrences.
- Trial name
- NCT06645262
- Testing
- Cryotherapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- Rehabilitation Centre Zivot
Patella-Dislocation, Patellofemoral Osteoarthritis
A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction
The operative management of chronic patellar instability has been controversial. Medial patellofemoral ligament reconstruction has gained success recently and might be superior to other soft-tissue procedures.
- Conditions
- Patella-Dislocation, Patellofemoral Osteoarthritis, Patellar Instability
- Trial name
- NCT00816647
- Testing
- Patellofemoral stabilizing surgery
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Finnish Defense Forces
Hip Fractures, Sleep
Researching the Effects of Sleep on STep Count dUring the Postoperative Period
Patients over the age of 65 who are admitted to the Juravinski Hospital for treatment of hip fractures will be invited to take part in the study.
- Conditions
- Hip Fractures, Sleep, Postoperative Complications, Delirium
- Trial name
- REST-UP (NCT03776526)
- Testing
- Fitbit® Alta HR Sleep monitoring
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Christopher Patterson
Ankle Sprains, Lateral Ankle Sprain
Study of the AxisBoard Single-Leg Balance Board in Adults With Lateral Ankle Sprain
The goal of this study is to learn whether a 28-day home exercise program using the AxisBoard Single-Leg Balance Board improves ankle function in adults who are still having symptoms 6 weeks to 6 months after a lateral (outer)…
- Trial name
- NCT07860125
- Testing
- AxisBoard Single-Leg Balance Board
- Volunteers
- 80 people
- Sponsor
- DITU Inc.
Spinal Cord Injuries
Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
Comparison of different types of transcranial magnetic stimulation techniques which are intermittent theta burst stimulation (iTBS) and high frequency repetitive transcranial magnetic stimulation (rTMS) in patients with spinal…
- Trial name
- NCT06248476
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hip Fracture
A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women
The purpose of this research study is to test if an experimental drug called ZT-031 can help men over 30 years or post-menopausal women over 55 years of age with certain types of hip fracture to heal better or faster following…
- Trial name
- SHIFT (NCT00787358)
- Testing
- ZT-031
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Zelos Therapeutics
Femoral Fractures
Observational Retrospective and Prospective Study on the Treatment of Femoral Fractures With EBA2
This is an observational, retrospective and prospective study where subjects who have undergone surgery with EBA2 medical device for lateral proximal femoral fractures will be followed for data collection since the day before…
- Trial name
- NCT01599221
- Testing
- EBA2
- Where
- 3 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Citieffe S.r.l
Ankle Injuries
The Effects of Open Versus Closed Kinetic Chain Exercises on Ankle Joint Function
The goal of this Randomized clinical trial is to find the effects of open versus closed kinetic chain exercises on ankle joint function in athletes with chronic ankle instability.
- Trial name
- NCT05717426
- Testing
- Open chain exercises, Closed kinetic chain exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Sehat Medical Complex
Femoral Neck Fracture, Hip Fracture
A Focused Registry on the Femoral Neck System (FNS) in Patients With Femoral Neck Fractures
In comparison to previous implants, the Femoral neck system (FNS) is an approved implant by the competent authorities (CE mark). It is designated to stabilize medial femoral neck fractures in a minimal invasive technique.
- Trial name
- FR_FNS (NCT02422355)
- Testing
- FNS
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 125 people
- Sponsor
- AO Innovation Translation Center
Pelvic Fractures, Acetabular Fractures
Incidence of Venous Thromboembolism in Patients With Pelvic and Acetabular Fractures (PAF)
The goal of this observational study is to investigate the incidence of venous thromboembolism (VTE) in patients with pelvic and acetabular fractures (PAF).
- Conditions
- Pelvic Fractures, Acetabular Fractures, Pelvic Trauma, Venous Thromboembolic Event
- Trial name
- PAF-VTE (NCT07165587)
- Testing
- Bilateral duplex ultrasonography
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Thromboembolism
Observational Study of Thrombogenic Properties in 220 Patients With Proximal Femur Fracture
Measurement of thrombogenic properties by TEG and MEA and observation of thrombotic events over 2 years in 220 patients with hip fracture.
- Trial name
- thro-fract15 (NCT02475187)
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Vestre Viken Hospital Trust
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Radiology Follow-up Study
Following recent advances in the understanding of successful anterior cruciate ligament (ACL) reconstruction, three important factors have been identified: femoral tunnel positioning, femoral tunnel aperture shape, and native…
- Trial name
- NCT02816606
- Testing
- Flexible reamers, 70-degree arthroscope
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® pH Point of Care Wound Diagnostic Test
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
- Trial name
- NCT04614038
- Testing
- DETEC® pH
- Where
- 2 sites in United States
- Volunteers
- 450 people
- Sponsor
- Progenitec Inc.
Hip Fractures
Blind Fascia Iliaca Compartment Block Compared to Ultrasound-guided Femoral Nerve Block in Patients With Hip Fractures
The goal of this study is to compare the analgesic effect of a blind fascia iliaca compartment block to an ultrasound-guided femoral nerve block in patients that present to the emergency department with hip fractures.
- Trial name
- NCT05365555
- Testing
- Fascia Iliaca Compartment Block, Femoral Nerve Block, Ropivacaine
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- University Hospital, Linkoeping