Clinical trials: Lower Urinary Tract Infection
Recurrent Urinary Tract Infection
Phase II Clinical Trial of Vitamin D3 for Reducing Recurrence of Recurrent Lower Urinary Tract Infections
The aim of this study was to initially evaluate the optimal dose, efficacy, and safety of vitamin D3 for reducing recurrence of recurrent urinary tract infections (rUTIs).
- Trial name
- NCT04859621
- Testing
- Vitamin D3 4000 IU, Vitamin D3 2000 IU, standard antibiotic therapy
- Where
- 6 sites in China
- Volunteers
- 150 people
- Sponsor
- Zensun Sci. & Tech. Co., Ltd.
Urinary Tract Infections, Urinary Tract Infection Lower Acute
Management of Acute Uncomplicated UTIs in Adults by Community Pharmacists
This study is to be conducted in community pharmacies. It involves the use of trained mystery patients to evaluate community pharmacists at baseline and post intervention.
- Trial name
- [UTI] (NCT05399797)
- Testing
- Educational training
- Where
- Nigeria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Urinary Tract Infections, Recurrent
Electroacupuncture for the Prevention of Recurrent Lower Urinary Tract Infection in Women
The goal of this clinical trial is to evaluate if electroacupuncture works to prevent recurrent lower urinary tract infections in female patients. It will also learn about the safety of electroacupuncture.
- Conditions
- Urinary Tract Infections, Recurrent, Electroacupuncture, Randomized Controlled Trial (RCT)
- Trial name
- rLUTI (NCT07507851)
- Testing
- Electroacupuncture
- Where
- 2 sites in China
- Volunteers
- 312 people
- Sponsor
- Yanjun Zhang, Baoyan Liu
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Stress Incontinence
Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
This project will determine whether post-operative prophylaxis with macrobid will decrease the incidence of postoperative urinary tract infection in women receiving sub-urethral slings for the treatment of urinary incontinence.
- Trial name
- NCT00734968
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overactive Bladder, Urinary Tract Infections
Comparison of Methods for Prevention of Urinary Tract Infection Following Botox Injection
Injection of OnabotulinumtoxinA (BTX-A) into the bladder is a widely used treatment option for patients with overactive bladder who have failed medical therapy.
- Trial name
- NCT03508921
- Testing
- Periprocedural Antibiotics, Extended Antibiotics, Injection of OnabotulinumtoxinA (BTX-A)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Vanderbilt University Medical Center
Urinary Retention, Neurogenic Bladder
Connected Catheter (C2P) Study for Bladder Management
The objective of this study is to evaluate the safety and essential performance of the C2P System in males with neurogenic lower urinary tract dysfunction (NLUTD), both in an acute clinical setting and an extended period of home…
- Trial name
- NCT03626324
- Testing
- C2P
- Where
- 8 sites in United States
- Volunteers
- 27 people
- Sponsor
- Spinal Singularity
Urinary Tract Infections
Nitrofurantoin and Urinary Tract Infections (UTIs)
Urinary tract infection (UTI) is the most common complication after surgery for prolapse or urinary incontinence. UTIs are painful and have the potential to turn into kidney infections.
- Trial name
- APPIC (NCT00678041)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Urinary Tract Infections
Clinical Effectiveness and Bacteriological Eradication of 4 Short-course Antibiotics for Uncomplicated UTIs in Women.
Randomized clinical trial in which women aged 18 or older and with symptoms of uncomplicated lower urinary tract infection and a positive urine dipstick analysis will be randomized to one of the following four groups: 2-day 3 g…
- Trial name
- SCOUT (NCT04959331)
- Testing
- Fosfomycin Trometamol Salt, Nitrofurantoin, Pivmecillinam
- Where
- 33 sites in Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Urinary Tract Infection
Role of Residual Urine and Asymptomatic Prostatitis in the Development of Urinary Tract Infections in Spinal Cord Injury
The purpose of this prospective study is to investigate the association between the amount of residual urine and asymptomatic bacterial prostate infection with the occurrence of recurrent (>2 /year) symptomatic urinary tract…
- Trial name
- NCT01601041
- Testing
- sonographic assessment of residual urine, urine culture
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
UTI - Urinary Tract Infection, UTI - Lower Urinary Tract Infection
Clinical Impact Analysis of PA-100 AST in a Spanish GP Setting
Assessment of workflow implications of the PA-100 AST System. Using well-defined data collection protocols, the study comprises the following: Collection of clean-catch midstream urine samples Measurement of specimens on the…
- Conditions
- UTI - Urinary Tract Infection, UTI - Lower Urinary Tract Infection, AMR, Cystitis Acute
- Trial name
- NCT07189429
- Testing
- PA-100 AST
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Sysmex Europe GmbH
Urologic Diseases, Urinary Tract Infections
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients
This is a single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa care (Komplexní lázeňská léčebně rehabilitační péče, KLP) on patients with nephrological and urological conditions treated at a spa…
- Conditions
- Urologic Diseases, Urinary Tract Infections, Nephrolithiasis, Nephrocalcinosis
- Trial name
- Uro-Nefro (NCT07435844)
- Testing
- Comprehensive Spa Care, Exercise Therapy, Dietotherapy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Spinal Cord Injury, Neurogenic Bladder (NB)
Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD
The main objective of the proposed research study is to determine in men and women with spinal cord injury/disease and neurogenic bladder whether the dose of coupled gentamicin \& Lactobacillus rhamnosus GG affects the…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder (NB), Neurogenic Lower Urinary Tract Dysfunction, Multiple Sclerosis
- Trial name
- NCT07643974
- Testing
- Gentamicin, Lactobacillus Rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Medstar Health Research Institute
Urinary Tract Infection Lower Acute
Clinical Study of Sanjin Tablets for the Treatment of Acute Simple Lower Urinary Tract Infection
The purpose of this study is to evaluate the efficacy, safety and immune mechanism of Sanjin tablets for the treatment of acute simple lower urinary tract infection and its influence on recurrence rate.
- Trial name
- NCT03658291
- Testing
- Sanjin tablets, Sanjin tablets simulants, Levofloxacin
- Volunteers
- 252 people
- Sponsor
- China Academy of Chinese Medical Sciences
HIV Seropositivity, Lower Urinary Tract Symptoms
Lower Urinary Tract Symptoms in Males Living With HIV
The primary aim of this study is to learn whether the frequency of lower urinary tract symptoms differ between the males with seronegativity for HIV and males living with HIV.
- Trial name
- NCT05964803
- Testing
- Questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Koç University
Urinary Tract Infections, Pelvic Organ Prolapse
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery
We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double-blinded randomized clinical trial…
- Conditions
- Urinary Tract Infections, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- NCT03522961
- Testing
- Cranberry capsules
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Brigham and Women's Hospital
Acute Lower Urinary Tract Infection
A Multi-center, Randomized, Double-blind, Double-dummy Clinical Study to Evaluate the Safety and Efficacy of Prulifloxacin Film-coated Tablet for the Treatment of Acute Uncomplicated Lower Urinary Tract Infection With Levofloxacin Hydrochloride Tablet as Active Control
prulifloxacin is not inferior to levofloxacin hydrochloride in treating acute uncomplicated lower urinary tract infection in chinese
- Trial name
- NCT02439632
- Testing
- prulifloxacin, Levofloxacin
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Lee's Pharmaceutical Limited
Infections, Urinary Tract
GSK2251052 in Complicated Urinary Tract Infection
This study is being conducted to evaluate the safety, efficacy (clinical and microbiological), pharmacokinetics/pharmacodynamics of GSK2251052 and to assess whether it would be a suitable antibiotic for the treatment for febrile…
- Trial name
- NCT01381549
- Testing
- GSK2251052, imipenem-cilastatin
- Where
- 24 sites in United States, Canada and 4 more
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infections
Safety, Tolerability, and PK of LBP-EC01 in Patients With Lower Urinary Tract Colonization Caused by E. Coli
Study LBx-1001 is a multi-center randomized, double-blind study to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of LBP-EC01 in patients with indwelling urinary catheters, or requiring…
- Trial name
- NCT04191148
- Testing
- LBP-EC01
- Where
- 7 sites in United States
- Volunteers
- 36 people
- Sponsor
- Locus Biosciences