Clinical trials: Lower Urinary Tract Symptoms
Overactive Bladder
At-Home Transcutaneous Tibial Nerve Stimulation for Overactive Bladder in Rural Women
This study contains a mixed-methods design consisting of a single-arm, interventional study and prospective patient interviews evaluating a novel self-implemented at-home Transcutaneous Tibial Nerve Stimulation (TTNS) treatment…
- Trial name
- NCT07178314
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Oregon Health and Science University
Benign Prostatic Hyperplasia
Pelvic Floor Muscle Exercise for Lower Urinary Tract Symptoms After Surgery for Benign Prostatic Hyperplasia.
This study aims to evaluate the effectiveness of pelvic floor muscle exercise (PFME) on improving lower urinary tract symptoms (LUTS), postvoid residual volume (PVR), and quality of life in patients undergoing surgery for benign…
- Trial name
- BPH LUTS PFME (NCT07293442)
- Testing
- pelvic floor muscle exercises
- Where
- 2 sites in Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei Medical University WanFang Hospital
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST
There are many evidences in the literature showing that the metabolic syndrome (MetS) is associated with BPH / LUTS. There are also numerous evidence that hypogonadism is associated with both conditions, thus being one of the…
- Conditions
- Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Hypogonadism
- Trial name
- PROTEST (NCT02366975)
- Testing
- Testosterone gel 2%
- Where
- 2 sites in Italy
- Volunteers
- 143 people
- Sponsor
- University of Florence
Bladder Injury, Ureter Injury
Comparison of Standard Cystoscopy With Carbon Dioxide Cystoscopy
For the evaluation of the lower urinary tract after laparoscopic hysterectomy, routine standard saline cystoscopy and carbon dioxide cystoscopy will be compared.
- Conditions
- Bladder Injury, Ureter Injury, Surgical Injury, Complication of Surgical Procedure
- Trial name
- NCT06278753
- Testing
- carbon dioxide cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 540 people
- Sponsor
- Tepecik Training and Research Hospital
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Pelvic Floor Disorders, Obstetric Trauma
Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth
This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into…
- Conditions
- Pelvic Floor Disorders, Obstetric Trauma, Urinary Incontinence, Anal Incontinence
- Trial name
- DeliverUU (NCT05530681)
- Testing
- Questionnaire, Pelvic floor ultrasound
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain, Stress Incontinence, Female
Nitrous Oxide for Analgesia During Office Urethral Bulking
This study is designed to determine primarily if there is a difference in perceived pain in patients receiving urethral bulking with calcium hydroxylapatite using local lidocaine versus local lidocaine plus nitrous oxide gas.
- Trial name
- NCT03847922
- Testing
- Nitrous Oxide + Oxygen Gas (Product), lidocaine gel 2%, Room air
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Baylor Research Institute
Urinary Incontinence
A Study of Incoxil Food Supplement in Female Patients With Stress Dominant Urinary Incontinence.
The purpose of this study is compare the effectiveness of Incoxil food supplement and pelvic floor muscle training with pelvic floor muscle training alone in the treatment of women with stress dominant urinary incontinence.
- Trial name
- NCT05358769
- Testing
- Incoxil food supplement and pelvic floor muscle exercise, Pelvic floor muscle exercise
- Where
- Hungary
- Volunteers
- 36 people
- Sponsor
- FEMPHARMA Kft.
Stress Urinary Incontinence, Surgery
The Impact of Postoperative Catheterization Time After Stress Incontinence Surgery to Success of Surgery
After incontinence surgery, the patients randomly will be divided two groups. In group A postoperative urinary catheterization time will be applied one day, In group B catheterization will be applied two days.
- Trial name
- NCT03225742
- Testing
- to measure the residual volume after catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Overactive Bladder
A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH)
The primary objective of the study was to investigate the efficacy of mirabegron versus placebo in male patients with OAB symptoms while taking the alpha blocker, tamsulosin, for BPH.
- Trial name
- NCT02656173
- Testing
- Mirabegron, Tamsulosin
- Where
- 58 sites in Japan, South Korea
- Volunteers
- 568 people
- Sponsor
- Astellas Pharma Inc
Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Clinical Trial to Evaluate the Efficacy and Safety of Naftopidil in Male Patients With Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
This study is designed to evaluate the efficacy and safety of Naftopidil in Korean male patients with with lower urinary tract symptoms associated with benign prostatic hyperplasia.
- Trial name
- NCT01922375
- Testing
- Naftopidil
- Where
- South Korea
- Volunteers
- 411 people
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Incontinence, Urge
T-DOC® NXT Clinical Investigation
Assessing the Performance, Safety and Usability of our Next Generation T-DOC® NXT Catheter for Performing Urodynamic Studies
- Trial name
- NCT03615001
- Testing
- TDOC NXT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laborie Medical Technologies Inc.
Overactive Bladder
"The Effectiveness of Transvertebral Magnetic Neuromodulation in Patients With Detrusor Overactivity"
The main hypothesis of this study is that magnetic neuromodulation can be used to correct bladder overactivity. The investigators assume that the transvertebral magnetic stimulation can improve both the subjective state of…
- Trial name
- NCT04578899
- Testing
- Transvertebral magnetic stimulation
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Joint-Stock Company North-West Center for Evidence-Based Medicine, Russian Federation
Urinary Stress Incontinence
Optimal Duration of Post-Operative Activity Restriction After Midurethral Sling Procedures
The purpose of this study is to compare postoperative outcomes and patient satisfaction between 3 and 6-week postoperative restrictions after a midurethral sling procedure.
- Trial name
- NCT04817839
- Testing
- 3-week post-operative activity restriction, 6-week post-operative activity restriction
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Yale University
Urinary Bladder, Overactive
Study to Test the Efficacy and Safety of YM178 in Subjects With Symptoms of Overactive Bladder
The study is intended to test efficacy, safety and tolerability of two doses of YM178 against placebo and tolterodine to treat patients with symptoms of over active bladder.
- Trial name
- Blossom (NCT01604928)
- Testing
- YM178, tolterodine
- Where
- 30 sites in Belgium, Czechia and 4 more
- Volunteers
- 260 people
- Sponsor
- Astellas Pharma Europe B.V.
Double Incontinence, Faecal Incontinence
Prospective Database of Factors Associated With Faecal vs. Double Incontinence in Patients Referred for High Resolution Anorectal Manometry.
This study aims to verify the results from our previous retrospective cohort analysis by establishing a database of well-characterised patients prospectively.
- Conditions
- Double Incontinence, Faecal Incontinence, Urinary Incontinence
- Trial name
- NCT05550675
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Urinary Incontinence, Stress
Fundación IVO Registry for Patients Undergoing Sling or Artificial Urinary Sphincter After Prostate Cancer Treatment
Stress urinary incontinence is a significant potential source of morbidity after radical prostatectomy or radiation therapy for prostate cancer. At present, artificial urinary sphincter remains the preferred therapeutic option.
- Trial name
- NCT02901392
- Testing
- AMS-800, ADVANCE/ADVANCEXP, VIRTUE
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Fundación Instituto Valenciano de Oncología
Obesity, Hypogonadism
Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients
The primary purpose of the study is to evaluate, in obese and hypogonadal patients eligible for bariatric surgery, the effect of testosterone replacement therapy in improving lower urinary tract symptoms (LUTS) assessed using the…
- Conditions
- Obesity, Hypogonadism, Prostatic Hyperplasia, Insulin Resistance
- Trial name
- NCT02248467
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Overactive Bladder Syndrome, Urinary Urge Incontinence
Platelet-Rich Plasma Versus Botulinum Toxin for Refractory Overactive Bladder: A Randomized Trial
Overactive bladder is a common condition that causes sudden urges to urinate, frequent urination, night-time urination, and sometimes leakage of urine.
- Conditions
- Overactive Bladder Syndrome, Urinary Urge Incontinence, Detrusor Overactivity
- Trial name
- NCT07184307
- Testing
- Platelet-Rich Plasma, Intravesical Botulinum Toxin Injection
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Benha University
Incontinence-associated Dermatitis
COPPER: A Trial Evaluating Copper-based Products for Incontinence-associated Dermatitis
As there are currently no evidence on the benefit of absorbing incontinence products with copper to stabilize IAD in the elderly, thus, this study will assess the capacity and safety of an absorbing incontinence products with a…
- Trial name
- NCT06726707
- Testing
- Diaper with a copper-based product + usual care, Barrier product with common diaper
- Sponsor
- Hospital Israelita Albert Einstein