Clinical trials: Lumbar Back Pain
Low Back Pain
Central Proprioceptive Processing and Postural Control in LBP
This project aims to elucidate neural correlates of proprioceptive deficits in patients with recurrent non-specific low back pain, by studying whether brain activation patterns during the processing of proprioceptive signals from…
- Trial name
- NCT03097718
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Low Back Pain, Low Back Pain, Mechanical
Effects of Mental Participation During Lumbar Stabilization and Neuromuscular Electrical Stimulation in Chronic Non-Specific Low Back Pain
This study was conducted to investigate the effects of incorporating synchronized voluntary muscle activation and active motor engagement during neuromuscular electrical stimulation (NMES) into a lumbar stabilization exercise…
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, NMES, Mental Perception
- Trial name
- NCT07857642
- Testing
- Exercise + NMES, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy Complications, Low Back Pain
An Intervention Program for the Trunk Neuromuscular Pattern and Postural Control in Pregnant With Low Back Pain
The relevance of this study is given by the feasibility to assess the effect of an intervention program based on the functionality and trunk neuromuscular activity and postural control in pregnant women with low back pain.
- Trial name
- NCT02933086
- Testing
- Specific exercises for lumbar stabilization, Conventional therapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Low Back Pain
Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation
Lumbar zygapophysial (facet) joint pain is a common cause of low back pain. Radiofrequency (RF) denervation is an effective and low risk treatment of chronic low back pain of suspected facet joint etiology.
- Trial name
- NCT00484159
- Testing
- Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine
- Where
- 2 sites in United States
- Volunteers
- 151 people
- Sponsor
- Johns Hopkins University
Chronic Low Back Pain (CLBP)
SENECA - Smart Therapies for Chronic Pain
This will be a randomized controlled prospective pilot study: The feasibility and usability of VIVO 2nd GEN therapy + Standard-of-Care (SoC) vs. Standard-of-Care alone will be evaluated.
- Trial name
- SENECA (NCT07628179)
- Testing
- VIVO 2nd GEN, Standard-of-Care Multimodal Pain Therapy
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Aurimod GmbH
Low Back Pain, Mechanical
Paracetamol, Dexketoprofen and Ibuprofen In Non-Traumatic Acute Low Back Pain
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of patients with Non-Traumatic Acute Low Back Pain The objective of the study is compare the…
- Trial name
- NCT04609254
- Testing
- Paracetamol, Dexketoprofen, Ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Pamukkale University
Chronic Pain, Low Back Pain
Meditation-CBT for Opioid-treated Chronic Low Back Pain
Chronic low back pain (CLBP) is one of the most common, costly and disabling conditions. It is often refractory to treatment, with patients requiring long-term opioid therapy.
- Trial name
- NCT01775995
- Testing
- Meditation-CBT Intervention + Usual Care, Usual Care Alone
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Wisconsin, Madison
Low Back Pain
Prevention and Treatment of Chronic Low Back Pain Through an Adapted Exercise Program
Objective: The purpose of this study is to investigate the effects of a adapted exercise program and general exercise recommendations compared with only general exercise recommendations for the management of chronic back pain…
- Trial name
- NCT02448888
- Testing
- Adapted exercise, General exercise recommendations
- Where
- 2 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Universidad San Jorge
Lumbar Radiculopathy, Pain, Intractable
Radiocontrast Media in the Pulsed Radiofrequency Treatment
Pulsed radiofrequency applied to the dorsal root ganglion (DRG) is an interventional treatment alternative in the treatment of lumbar radicular pain that does not respond to conservative methods.
- Trial name
- NCT04876469
- Testing
- Pulsed Radiofrequency treatment of the lumbar dorsal root ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome
Efficacy of Pregabalin in Patients With Radicular Pain
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
- Conditions
- Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome, Spinal Stenosis, Herniated Disc
- Trial name
- NCT00908375
- Testing
- Pregabalin, Sugar Pill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Northwestern University
Low Back Pain, Pain
D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of D-cycloserine versus placebo in relieving the signs and symptoms of patients with chronic lower back pain.
- Trial name
- NCT03535688
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Northwestern University
Chronic Nonspecific Low Back Pain
Effects of SIS Therapy in Individuals With Chronic Nonspecific Low Back Pain
Brief Summary - buraya yapıştırın Chronic nonspecific low back pain is a common condition that can cause pain, limitations in daily activities, and reduced quality of life.
- Trial name
- NCT07839169
- Testing
- SIS Therapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Back Pain, Low, Degenerative Disc Disease
Protocol for an Analytical Study With Microbiological, Phenotypic, Genotypic and Multiomics Techniques
The study aims to identify metabolites present in intervertebral discs colonized by C. acnes from patients with low back pain and degenerative disc disease, correlating them with their clinical, radiological and demographic…
- Trial name
- NCT05090553
- Testing
- Lumbar Spinal Fusion Surgery, Bacterial culture, Phenotypic and genotypic characterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Gaffree & Guinle Universitary Hospital
Chronic Pain, Low Back Pain
Searching for the Optimal tDCS Target Combined With Peripheral Electrical Stimulation in Chronic Low Back Pain
Low back pain (LBP) has been associated with severe impairments, primarily related to activities of daily living, functional ability and quality of life.
- Trial name
- NCT04496661
- Testing
- Transcranial Direct Current Stimulation on M1 and Peripheral Electrical Stimulation, Transcranial Direct Current Stimulation on DLPFC and Peripheral Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Lumbar Disc Herniation
Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine
This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.
- Trial name
- NCT03236753
- Testing
- Thread-embedding Acupuncture (TEA)
- Where
- 4 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Kyunghee University Medical Center
Low Back Pain
Effects of a Mat Pilates Exercise Program on Elderly Women With Chronic Nonspecific Low Back Pain
The technique of Pilates exercises on a mat has proven to be effective and practically applicable to patients with chronic back pain. However, its application in women over 65 years has not been adequately studied.
- Trial name
- NCT04752579
- Testing
- Pilates exercise program
- Where
- Greece
- Volunteers
- 63 people
- Sponsor
- Aristotle University Of Thessaloniki
Low Back Pain
Relaxation Exercises for Low Back Pain and Insomnia in the Third Trimester of Pregnancy
The role of progressive muscle exercises has been widely explored. However, limited studies report its effectiveness in pregnant women in their third trimester suffering from pain and insomnia that may or may not be due to that…
- Trial name
- NCT05475327
- Testing
- Conventional Physical Therapy, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Chronic Low Back Pain (CLBP)
Art Therapy for Adults With Chronic Low Back Pain
This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).
- Trial name
- NCT07141069
- Testing
- Art therapy combined with Exercise, Exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Low Back Pain
Study of the Efficacy of Manual Therapy for a Subgroup of Acute Non-specific Low Back Pain
The purpose of this study is: To validate or not the interest of the classification using the pragmatic application of clinical predictive rule for low back pain to identify patients with good prognosis following a brief spinal…
- Trial name
- NCT01801553
- Testing
- Spinal manipulation, Usual medical care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
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