Clinical trials: Lumbar Back Pain
Lumbago
Treatment of Mechanical Low Back Pain With High-Intensity Focused Ultrasound (HIFU)
High-intensity focused ultrasound (HIFU) is an emerging technology that allows for the targeted thermal ablation of deep tissues in a non-invasive manner, by concentrating acoustic energy on the target nerve, whilst preserving…
- Trial name
- NCT07467408
- Testing
- High-Intensity Focused Ultrasound of the medial lumbar branch
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Consorci Sanitari de Terrassa
Low Back Pain, Neck Pain
IPM Procedures With or Without Fluoroscopy: Outcome Comparison
To determine clinically significant improvement in the patients undergoing procedures under fluoroscopy. To evaluate and compare the adverse event profile in both groups
- Trial name
- NCT00371618
- Testing
- Fluoroscopy
- Where
- United States
- Sponsor
- Pain Management Center of Paducah
Low Back Pain
Exercise Intervention for Unilateral Amputees With Low Back Pain
A three-month, randomized, controlled study will be used to examine the effects of a home-based resistance exercise program on improving pain severity and functional ability in unilateral lower extremity amputees who suffer from…
- Trial name
- NCT03300375
- Testing
- Home exercise program, Post Op instructions
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Chronic Low-back Pain
Effectiveness of Pain Neuroscience Education on Clinical and Psychosocial Variables in Chronic Low Back Pain
An educational intervention on the neurophysiology of chronic pain will be provided. The content of the intervention will be identical in the experimental groups (group and individual).
- Trial name
- NCT05953454
- Testing
- Pain neuroscience Education
- Volunteers
- 69 people
- Sponsor
- Universidad Santo Tomas, Chile
Disc Degenerative Disease, Back Pain
Intradiscal rhGDF-6 for the Treatment of Lumbar Disc Degeneration
The goal of this clinical trial is to find out if a new medicine can help people who have long-lasting back pain caused by damaged spinal discs. The study will also check if the medicine is safe to use.
- Trial name
- CBT005 (NCT07668466)
- Testing
- High Dose, Low Dose
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Cartago Biotech Pty Ltd
Lower Back Pain
Investigating the Effects of a Spinal Mobilisation Intervention in People With Lower Back Pain
The objective of the study is to measure and analyse the effect of a spinal mobilisation intervention on muscle tissue quality in people with lower back pain.
- Trial name
- NCT04012970
- Testing
- Manual spinal mobilisations
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Edinburgh Napier University
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anterior Pelvic Tilt, Low Back Pain
Comparing Different Physiotherapy Interventions on APT in Non Specific Low Back Pain
Anterior pelvic tilt (APT) is a prevalent postural deviation characterized by excessive forward rotation of the pelvis, often resulting in increased lumbar lordosis.
- Trial name
- NCT07098741
- Testing
- Core stability exercises with electrotherapy, Soft tissue release with manual therapy and stretching, Postural correction exercises with contrast therapy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- National Orthopedic and General Hospital
Low Back Pain
Back Beliefs Among the General Population
In the current study we aim to evaluate the effects of a short educational video on improving the belief that "the back is fragile and needs to be protected" among the German speaking Swiss general population.
- Trial name
- NCT06104995
- Testing
- Interventional video, Control video
- Where
- Switzerland
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Chronic Low Back Pain
Rage Against the Pain to Address Chronic Low Back Pain Among Veterans
Chronic low back pain is a leading cause of disability among Veterans. Yoga is recommended as a front-line treatment option for chronic low back pain and is available across the VA healthcare system; however, despite yoga being…
- Trial name
- RAP (NCT05103475)
- Testing
- Rage Against the Pain (RAP), Control
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain (Non-specific, Uncomplicated), Chronic Low Back Pain (CLBP)
Chronic Low Back Pain Comorbidities: Unravelling Impaired Glucose Metabolism
Chronic low back pain (CLBP) is a global health problem. The first step for developing effective treatments is a better understanding of underlying mechanisms, including its comorbidities.
- Trial name
- GLOW (NCT07734714)
- Testing
- Glucose beverage, Isomaltulose beverage, Standardized breakfast
- Where
- Belgium
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain, Acute
Interfascial Infiltration for Acute Unspecific Low Back Pain in the Emergency Department
Pain relief and functional impairment have been shown to remain poor to moderate over weeks after emergency department discharge, in patients who seek ED management for acute nontraumatic, nonradicular low back pain.
- Trial name
- PreSosLumbago (NCT03968185)
- Testing
- Interfascial infiltration, Standard medical treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis, Rheumatoid Arthritis
Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity
This is a phase IV, open-label and single-arm study of patients with non-malignant pain due to osteoarthritis, rheumatoid arthritis, low back pain and joint/muscle pain, who were not responding to non-opioid analgesics.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT02519387
- Testing
- Buprenorphine Transdermal Patch
- Where
- 3 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Mundipharma Pharmaceuticals Sdn. Bhd.
Chronic Low Back Pain
Aquatic Exercises for Patients With Chronic Low Back Pain
The goal of this study is to compare the effect of aquatic exercises (AEG) to the aquatic exercises plus aerobic training (deep-water running) (AEDWRG) on functional status and pain in patients with specific chronic low back pain.
- Trial name
- NCT02422693
- Testing
- Aquatic Exercises, Deep-water running
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Universidade Estadual de Londrina
Back Problems and Other Musculoskeletal Injuries
Injury Prevention Among Conscripts
The purpose of this clinical trial is to study the effect of neuromuscular training program and regular safety counselling on the risk of musculoskeletal injuries in adolescent conscripts.
- Trial name
- VASTE (NCT00595816)
- Testing
- physical training and counselling
- Where
- 2 sites in Finland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Lower Back Pain
Safety and Performance of the Elaspine System in the Treatment of the Lumbar Spine
The safety and performance of the Elaspine™ Implant System in the treatment of lower back pain will be evaluated with a prospective and nonrandomized, multicenter post-marketing clinical study (PMCS).
- Trial name
- NCT01323543
- Testing
- Elaspine™
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 40 people
- Sponsor
- Spinelab AG
Low Back Pain
Clinical Prediction Rule for Clinical Lumbar Instability
The aim of this study is to determine if assessment of additional measures of trunk neuromuscular control will improve the ability to identify patients with low back pain who successfully respond to trunk stabilization exercises.
- Trial name
- NCT01085448
- Testing
- Core Stabilization
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Drexel University
Postoperative Acute Pain, Lumbar Degenerative Diseases
Liposomal Bupivacaine for Pain After Lumbar Fusion
Spine surgery often causes severe postoperative pain. Currently, our hospital routinely uses ropivacaine for local infiltration analgesia (lasting 6-8 hours).
- Trial name
- NCT07171125
- Testing
- Liposomal bupivacaine (local infiltration), ropivacaine (local infiltration)
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Min Li
Low Back Pain
Effectiveness of Different Weekly Frequency of Modified Pilates Method Exercises in the Treatment of Chronic Nonspecific Low Back Pain
Low back pain is a major cause of disability and absenteeism and the supervised exercise is a recommended treatment by the guidelines and has been cost-effective.
- Trial name
- NCT02241538
- Testing
- Pilates 1, Pilates 2, Pilates 3
- Where
- Brazil
- Volunteers
- 296 people
- Sponsor
- Universidade Cidade de Sao Paulo
Discogenic Pain, Platelet-rich Plasma
Platelet-rich Plasma for Low Back Pain
This study aims to evaluate the effect of platelet-rich plasma (PRP) on discogenic low back pain by comparing the pre- and post-interventional outcomes in patients receiving intradiscal injection of autologous PRP.
- Trial name
- NCT03197415
- Testing
- Platelet-rich plasma
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Pei-Yuan Lee, MD
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