Clinical trials: Lumbar Back Pain
Spinal Stenosis, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis
This study tests the effectiveness of different treatments for the three most commonly diagnosed conditions of the lower backbone (lumbar spine).
- Trial name
- NCT00000411
- Testing
- Decompressive laminectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 289 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Motivational Interviewing
Motivational Interviewing in Physiotherapy for Patients With Low Back Pain
This study aims to evaluate the efficacy of motivational interviewing (MI) on adherence to exercises and on levels of pain and incapacity in patients who engage in physiotherapy for low back pain.
- Trial name
- HELENA (NCT03399409)
- Testing
- Motivational Interviewing, Anti-inflammatory Information
- Volunteers
- 60 people
- Sponsor
- Universidade do Porto
Back Pain, Low
Effects of Myofascial Release Therapy and Endurance Training on Mechanical Back Pain
This study is a randomized clinical trial to determine the effects of myofascial release therapy versus endurance training of trunk extensor muscles on pain, disability and muscle endurance in patients with mechanical back pain.
- Trial name
- NCT05272098
- Testing
- Group A will receive myofascial release therapy + conventional physical therapy, Group B will receive endurance training of the trunk extensor muscles + conventional physical therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Nonspecific Low Back Pain
Active Release Versus Positional Release Technique
Chronic Non-Specific Low Back Pain is the pain with tension, soreness or stiffness of lower back muscles lasting from 3 months or longer due to off unidentifiable cause.
- Trial name
- NCT07756021
- Testing
- Positional Release Therapy, Active Release Therapy, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Rashid Latif Medical College
Chronic Low Back Pain
Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
The purpose of this study is to determine the efficacy and safety of EN3324 (axomadol) in subjects with moderate to severe chronic low back pain
- Trial name
- CLBP (NCT01043263)
- Testing
- EN3324 (axomadol)
- Where
- 59 sites in United States
- Volunteers
- 236 people
- Sponsor
- Grünenthal GmbH
Low Back Pain
Effect of Progressive Muscle Relaxation Exercises Versus Pilates Exercises on Postnatal Low Back Pain
This study was conducted to compare between the effect of progressive muscle relaxation exercises and the effect of pilates exercises on postnatal low back pain
- Trial name
- NCT06284018
- Testing
- Progressive Muscle Relaxation Exercises, Pilates Exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Exercise Therapy, Low Back Pain
Personalized Physical Back Training Program to Improve Physical Functioning in People With Non-specific Low Back Pain
Personalized medicine and individualized therapeutic approaches are prominent in current research. But are these approaches also effective for treating non-specific low back pain (NSLBP)? NSLBP is one of the most common…
- Trial name
- LIFDI (NCT06938568)
- Testing
- Personalized back exercises, Non-personalized back exercises
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- Claudio Perret
Low Back Pain
Multifidus PET Scan Study
The study involves investigating phenotypic changes (ie metabolic activity in brain pain matrix areas, metabolic activity and textural analysis of multifidus muscle) following multifidus stimulation and establishing relationship…
- Trial name
- MUST (NCT04327817)
- Testing
- Multifidus stimulator
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Chronic Low Back Pain, Mechanical Low Back Pain
Use of Biofeedback Training to Correct Abnormal Neuromechanical Pattern in Chronic Low Back Pain Patients
The purpose of the present study is to evaluate the benefit of biofeedback training on the capacity of chronic low back pain patients to decrease their lumbar paraspinal muscles activity during trunk full flexion and its…
- Trial name
- NCT02239289
- Testing
- Biofeedback
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Université du Québec à Trois-Rivières
Non-specific Chronic Low Back Pain, Healthy Volunteer
Behavioral Indicators of Pain Representation
The goal of this observational study is to compare the postural response to the mental simulation of everyday situations identified as painful in participants with non-specific low back pain and healthy volunteers.
- Trial name
- ICOR (NCT06669767)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Chronic Low Back Pain
Personalized and Automated Digital Coaching in People With Non-specific Chronic Low Back Pain
The investigators hypothesize that a personalized and automated digital coaching could reduce activity limitations in people with chronic low back pain as compared to usual care
- Trial name
- BACK-4P (NCT06498271)
- Testing
- Personalized and automated digital coaching using a mobile application
- Where
- France
- Volunteers
- 330 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Low Back Pain
Effects of Association of Trunk Stretching and Segmental Stabilization Exercises in Chronic Unspecific Low Back Pain
The incidence of chronic nonspecific low back pain is the highest in the world population and can lead to disability. One of the standards treatments for this condition is the segmental stabilization exercises, as well as trunk…
- Trial name
- NCT02985892
- Testing
- SSASG, SSPSG
- Where
- 2 sites in Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Low Back Pain
Effects of Pain Neuroscience Education With Sensory Discrimination Training Among Patients With Chronic Low Back Pain
The current study is a double-blind, parallel-group randomized controlled trial involving 80 participants with chronic low back pain.
- Trial name
- NCT07284407
- Testing
- Pain Neuroscience Education with Sensory Discrimination Training and Core Stability Exercises, Pain Neuroscience Education and Core stability Exercises
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Low Back Pain
Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain
To evaluate efficacy of Finalgon® cream (1.08% Nicoboxil/ 0.17% Nonivamide) versus placebo in patients with acute low back pain.
- Trial name
- NCT02300311
- Testing
- nonivamide + nicoboxil (Finalgon cream)
- Where
- 8 sites in Russia, Ukraine
- Volunteers
- 138 people
- Sponsor
- Boehringer Ingelheim
Non-specific Low Back Pain (NSLBP)
Effects Of Sahrmann's Versus McGill Exercise In Patients With Non-Specific Low Back Pain
The goal of this clinical trial is to learn whether Sahrmann exercises or McGill exercises are more effective for reducing pain and improving function in adults with non-specific low back pain.
- Trial name
- NCT07659327
- Testing
- Sahrmann's Exercises, McGill Exercises
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
INTRACEPT: Prospective, Randomized, Multi-center Study Intraosseous Basivertebral Nerve Ablation for Treatment of CLBP
Prospective, open-label, 1:1 randomized controlled trial of Basivertebral nerve (BVN) Ablation arm vs Standard Care Control for the treatment of vertebrogenic chronic low back pain (CLBP).
- Trial name
- CLBP (NCT03246061)
- Testing
- Intracept System, Standard Care
- Where
- 18 sites in United States
- Volunteers
- 140 people
- Sponsor
- Relievant Medsystems, Inc.
Lower Back Pain
Treatment of Back Pain Using Transcutaneous Magnetic Stimulation (TCMS)
This is a single-site, randomized, Single-blinded, placebo-controlled, trial of Transcutaneous Magnetic Stimulation (TCMS) for the treatment of lower back pain.
- Trial name
- NCT02421757
- Testing
- Fischell Transcutaneous Magnetic Stimulation Pain Treatment Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Chronic Low Back Pain (CLBP)
How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain
This pilot study will examine whether osteopathic manipulative treatment (OMT) can improve both physical and psychological aspects of chronic low back pain by focusing on the interconnected myofascial system of the back, legs…
- Trial name
- NCT07193212
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Low Back Pain
Effects of Osteopathic Treatment With Cognitive Training on Low Back Pain
The objective of this study is to verify whether the combined approach (osteopathic manipulative treatment -OMT- and cognitive training -CT) is more effective in the long term than the individual approaches (OMT or CT) in…
- Trial name
- NCT04277039
- Testing
- osteopathic treatment + cognitive training, osteopathic treatment, usual care
- Where
- 3 sites in Italy
- Volunteers
- 216 people
- Sponsor
- Come Collaboration
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