Clinical trials: Lumbar Back Pain
Osteoarthritis, Knee, Diabetic Neuropathic Pain
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs).
- Conditions
- Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
- Trial name
- CPMP (NCT05986292)
- Testing
- LY3016859 ISA, LY3556050 ISA, LY3526318 ISA
- Where
- 64 sites in United States, Puerto Rico
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Degenerative Disc Disease
Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain
The purpose of this study is to compare two doses of immunoselected, culture-expanded, nucleated, allogeneic adult MPCs when combined with hyaluronic acid to two control intradiscal injections in subjects with chronic low back…
- Trial name
- NCT01290367
- Testing
- Single Dose MPCs Injection, Single injection of saline solution, Single injection of hyaluronic acid
- Where
- 14 sites in United States, Australia
- Volunteers
- 100 people
- Sponsor
- Mesoblast, Ltd.
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Neck Pain, Low Back Pain
Effects of Percutaneous Peripheral Nerve Stimulation on Neck and Low Back Pain
Percutaneous Peripheral Nerve Stimulation (pPNS) is a physical therapy technique, whose main objective is to treat neuro-musculo-skeletal signs and symptoms by applying a current to a peripheric nerve with a blunt dry needle.
- Trial name
- NCT06153875
- Testing
- Sensory Thresold, Burst High Frecuency, Theta-Burst Stimulation, Transcutaneous Electrical Nerve Stimulation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clinica Francisco Ortega Rehabilitacion Avanzada SL
Chronic Low Back Pain
ReActiv8 for Chronic Low Back Pain (PMCF)
The purpose of this Clinical Study is to investigate the effect of electrical stimulation for chronic low back pain.
- Trial name
- ReActiv8-A (NCT01985230)
- Testing
- ReActiv8 Implantable Stimulation System implanted and activated.
- Where
- 15 sites in Australia, Belgium and 1 more
- Volunteers
- 96 people
- Sponsor
- Mainstay Medical
Pain
Blood Sample Donations to Study the Role of Genes in Pain
This study attempts to identify genes that may increase or decrease the likelihood of sciatic pain (shooting pain down the leg) persisting 1 year after treatment of a herniated spinal disc.
- Trial name
- NCT00341367
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Degenerative Disc Disease, Chronic Low-back Pain
Safety Study for An Artificial Disc Nucleus Replacement to Treat Chronic Low Back Pain
This study will be a prospective, open-label, multi-center study that will collect safety data for the minimally invasive PerQdisc Nucleus Replacement Device deployed to reduce chronic low back pain.
- Trial name
- NCT04004156
- Testing
- PerQdisc® Nucleus Replacement Device.
- Where
- 4 sites in Belgium, Canada and 2 more
- Volunteers
- 9 people
- Sponsor
- Spinal Stabilization Technologies
Low Back Pain
Assessment of Acupuncture to Improve Function, Exercise Capacity, and Pain
The purpose of this research proposal is to conduct a feasibility study to determine the viability a larger efficacy study of combined acupuncture treatments plus treadmill exercise to decrease pain, facilitate exercise, and…
- Trial name
- NCT00502619
- Testing
- Acupuncture, Treadmill Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Maryland Health Care System
Low Back Pain, Diaphragm
The Effect of Diaphragm Muscle Training on Chronic Low Back Pain
Brief Summary: Low back pain is very common problem in all the developed countries and affects children to elderly. Based on the etiology the low back pain is divided into two type: nonspecific and specific low back pain.
- Trial name
- LBP_DT (NCT03600207)
- Testing
- Complex training, Diaphragm training
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Szeged University
Low Back Pain
Development and Validation of the Italian Version of the Waddell Chronic Disability Index for People With Low Back Pain
This prospective observational study aims to develop and validate an Italian version of the Waddell Disability Index (WDI-I), a self-administered questionnaire designed to assess disability related to chronic low back pain.
- Trial name
- NCT07413107
- Where
- 2 sites in Italy
- Volunteers
- 115 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Low Back Pain
Predictive Factors for the Success of Rehabilitation Programs in Chronic Low Back Pain
Chronic low back pain is the leading cause of years lived with disability in the world among 19-49 year olds. The usual progression leads to 15% of acute episodes of persistent pain and more than 50% of persistent activity…
- Trial name
- APPROCHE (NCT07051772)
- Testing
- mobility skills testing session
- Where
- 6 sites in France
- Volunteers
- 333 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Pain
The Effect of Chronic Pain and Its Treatment on Quality of Life and Physical Activity
Chronic pain is pain whose duration usually exceeds a period of three months and standard treatment is ineffective. This pain brings many changes in physical and psychological functioning to the individual and can even lead to a…
- Trial name
- NCT05922007
- Testing
- Validation of the Questionnaire, Prospective quantitative study - questionnaire survey
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Ostrava
Low Back Pain, Mechanical, Chronic Low-back Pain
Effectiveness of Pressure Biofeedback Therapy and Progressive Muscle Relaxation Technique in Improving Pain and Disability Among Patients With Non-Specific Low Back Pain
Low back pain is common MSK disease with prevalence of 60 to 70 percent. Patients with low back discomfort are typically treated conservatively by physical therapists.
- Conditions
- Low Back Pain, Mechanical, Chronic Low-back Pain, Mechanical Low Back Pain, Lower Back Pain Chronic
- Trial name
- NCT05616702
- Testing
- Pressure Biofeedback Therapy + Progressive Muscles Relaxation + thermotherapy, Progressive Muscles Relaxation + thermotherapy
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Low Back Pain
Comparative Effect of Sahrmann's Exercises and Core Stabilization Exercises on Low Back Pain in Individuals With Lumbar Lordosis
Comparative effect of Sahrmann's exercises and core stabilization exercises on low back pain in individuals with lumbar lordosis
- Trial name
- NCT07564765
- Testing
- Sahrmann's Exercises, Core Stabilization Exercises
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Rashid Latif Medical College
Simulation Training
Simulation in Physical Therapy Students
This randomized trial included physiotherapy students, randomized in two groups, experimental one included simulation for developed competencies related to clinical reasoning in physiotherapy interventions for people with low…
- Trial name
- NCT04428892
- Testing
- Pedagogyc Strategy
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Universidad de la Sabana
Low Back Pain
Exercise for Low Back Pain in Children
This study aimed to determine the efficacy of an eight-week specific exercise programme in reducing self-reported episodes and intensity of LBP, as well as modifying some of the identified risk factors for LBP, in children.
- Trial name
- LBP (NCT00786864)
- Testing
- exercise programme
- Where
- South Africa
- Volunteers
- 72 people
- Sponsor
- University of Witwatersrand, South Africa
Low Back Pain
The Effect of Physical Therapy Program and Erector Spina Plane Block in Patients With Degenerative Lumbar Scoliosis
Degenerative (de novo) scoliosis is the result of a long and multifactorial process that occurs through degenerative change in the aging population without a pre-existing spinal deformity.
- Trial name
- NCT06018402
- Testing
- physical therapy, physical therapy + espb
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Low Back Pain
Study to Investigate the Potential Pharmacological Effect of Oral Palmitoylethanolamide (PEA) Therapy in the Management of Low Back Pain (Neuropathic Pain)
This clinical trial aims to evaluate the potential therapeutic effects of oral supplemental Palmitoylethanolamide (PEA) Phytosome® in managing neuropathic low back pain.
- Trial name
- NCT06694337
- Testing
- 300 mg Palmitoylethanolamide (PEA) Phytosome®, 450 mg Palmitoylethanolamide (PEA) Phytosome®, Control group
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Lower Back Pain, Degenerative Disc Disease (DDD)
Luna Interbody System for Fusion Trial
The purpose of this trial is to evaluate the performance, safety and effectiveness of the Luna system for the treatment of degenerative disc disease.
- Trial name
- LIFT (NCT01551901)
- Testing
- Spinal fusion
- Where
- 5 sites in Belgium, Germany
- Volunteers
- 100 people
- Sponsor
- Benvenue Medical, Inc.
Chronic Low Back Pain
The Effect of Cognitive Functional Therapy on Patients With Non-specific Chronic Low Back Pain
The purpose of this study is to evaluate whether individual cognitive functional therapy (CFT), when compared to group exercise classes is effective in reducing pain and disability in patients with non-specific chronic low back…
- Trial name
- NCT02145728
- Testing
- Individual Cognitive Functional Therapy, Group Exercise Classes
- Where
- 3 sites in Ireland
- Volunteers
- 208 people
- Sponsor
- University of Limerick
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