Clinical trials: Lumbar Decompression
Spinal Fusion, Chronic Lower Back Pain
Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery
After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating…
- Trial name
- NCT06282770
- Testing
- Laser Diode Brace
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Low Back Pain, Lumbar Spinal Stenosis
Improvement of Low Back Pain After Decompression in Patients with Degenerative Spinal Canal Stenosis
Degenerative lumbar spine disease is a leading cause of disability in the world; it encompasses conditions such as spondylolisthesis, disc degeneration, and lumbar spinal stenosis.
- Trial name
- NCT05791422
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Assiut University
Lumbar Spinal Stenosis
Effects of X-STOP® Versus Laminectomy Study
To determine if the effectiveness of the X-STOP® implant is equivalent (non-inferior) to that of conventional laminectomy in patients with lumbar spinal stenosis as measured by the Zurich Claudication Questionnaire.
- Trial name
- EXELS (NCT00558129)
- Testing
- X-STOP®, Laminectomy
- Sponsor
- Medtronic Spine LLC
Spinal Stenosis Lumbar
Coflex PS3 Actual Conditions for Use Study
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA…
- Trial name
- PAS003 (NCT02555280)
- Testing
- coflex® Interlaminar Technology, Decompression
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Companion Spine, LLC
Lumbar Spinal Stenosis
Efficiency of Surgical Treatment for Lumbar Spinal Stenosis
Decompression surgery has proved to be effective for Lumbar Spinal Stenosis (LSS) with persistent pain. But the efficiency of the surgery for degenerated LSS remain uncertain and is the subject of this study.
- Trial name
- NCT03365401
- Testing
- decompression surgery, nonsurgical treatment
- Volunteers
- 150 people
- Sponsor
- Peking University People's Hospital
Lumbar Spinal Stenosis
Microdecompression Versus Open Laminectomy and Posterior Stabilization for Multilevel Lumbar Spine Stenosis
This study compare the results of 2 methods in surgical treatment of Lumbar spine stenosis.These are microdecompresssion and open decompression with posterior stabilization.
- Trial name
- NCT04087694
- Testing
- Microdecompression
- Volunteers
- 100 people
- Sponsor
- Hawler Medical University
Lumbar Spondylolisthesis Involving L4-L5
Survivorship of Decompression Alone Vs Decomp With Fusion in DLS and LCS
There has been a long-standing controversy on the operative treatment of Degenerative Lumbar Spondylolisthesis (DLS) with Lumbar Canal Stenosis (LCS), especially whether the addition of fusion to decompression is necessary.
- Trial name
- NCT05386381
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Cranial Nerve Diseases, Facial Neuralgia
CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
Even at centers with very large experience, the risk of cerebrospinal fluid (CSF) leakage in surgery for microvascular decompression is reported up to 3%. Prevention of leakage is important since meningitis may follow.
- Conditions
- Cranial Nerve Diseases, Facial Neuralgia, Trigeminal Neuralgia, Hemifacial Spasm
- Trial name
- NCT01932255
- Testing
- prophylactic spinal tap, no prophylactic spinal tap
- Sponsor
- St. Olavs Hospital
Lumbar Degenerative Spondylolisthesis
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis.
- Trial name
- NCT07289737
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Spinal Stenosis
The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology
The purpose of the coflexCOMMUNITY observational study is to collect information on patients with spinal stenosis undergoing back surgery with the coflex® implant, and to look at their outcomes and the cost-effectiveness of this…
- Trial name
- NCT02457468
- Testing
- coflex
- Where
- 28 sites in United States
- Volunteers
- 325 people
- Sponsor
- Predicted, Reported and Observed Outcomes Foundation
Lumbar Decompression
Ambulatory Geriatric Endoscopic Spine
The research focuses on evaluating the clinical outcomes of endoscopic lumbar decompression surgery performed in an outpatient setting for patients over 75 years old.
- Trial name
- AGES (NCT06523426)
- Testing
- Patient treated by spinal endoscopy
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Lumbar Posterior Decompression
Thoracolumbal Interfascial Plane Block Versus Erector Spinae Plane Block for Lumbar Posterior Decompression Stabilization
This study aimed to found out The Comparison Of Perioperative Analgesia Effectiveness Between Thoracolumbal Interfascial Plane Block with Erector Spinae Plane Block In Lumbar Posterior Decompression and Stabilization.
- Trial name
- NCT04951024
- Testing
- Thoracolumbar interfacial plane (TLIP) Block, Erector Spinae Plane (ESP) Block
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
LUMBAR STENOSIS
Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Stenosis of symptomatic lumbar canal is presented as a series of degenerative changes affecting the various vertebral segment structures, including: a joint zigoapofisária, yellow ligament, the articular capsule and the…
- Trial name
- Stenosis (NCT02879461)
- Testing
- LUMBAR DESCOMPRESSION
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Federal University of São Paulo
Degenerative Lumbar Spinal Stenosis
Segmental Decompression Versus Wide Decompression With Fixation for Degenerative Lumbar Canal Stenosis
The purpose of this study is to compare two different surgical techniques for treating degenerative lumbar canal stenosis, a condition where the lower spinal canal narrows and puts pressure on the spinal nerves.
- Trial name
- NCT07542054
- Testing
- Segmental Decompression, Wide Decompression with Fixation
- Volunteers
- 56 people
- Sponsor
- Assiut University
Degenerative Lumbar Spondylolisthesis
Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up
In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial.
- Trial name
- DS-registry (NCT03469791)
- Testing
- Surgical treatment of Degenerative Spondylolisthesis
- Where
- Norway
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Lumbar Spinal Stenosis, Spinal Stenosis
Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Long-term clinical results of two methods of surgical treatment (spinal decompression with or without fusion) in patients with single-level lumbar stenosis will be compared.
- Conditions
- Lumbar Spinal Stenosis, Spinal Stenosis, Spinal Fusion
- Trial name
- NCT05273879
- Testing
- decompression, fusion
- Where
- 2 sites in Russia
- Volunteers
- 86 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Lumbar Spinal Stenosis
The STEPS - Totalis™ Trial
The purpose of this study is to determine safety and effectiveness, as measured by changes in pain, disability, patient satisfaction, and claudicatory symptoms, at 6 months following treatment with the Totalis™ Direct…
- Trial name
- NCT02079038
- Testing
- Totalis, Comparator Surgical Procedure
- Where
- 19 sites in United States
- Volunteers
- 180 people
- Sponsor
- VertiFlex, Incorporated
Lumbar Spine Disease
Effectiveness of Home Programs After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who are followed up by Bursa Çekirge State Hospital Cekirge State Hospital Neurosurgery outpatient clinic and who have undergone lumbar decompression surgery and who meet the…
- Trial name
- NCT06014645
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Muğla Sıtkı Koçman University
Lumbar Spinal Stenosis, Surgery
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis
Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment.
- Trial name
- NCT04254757
- Testing
- Two different treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Postoperative Pain
Erector Spinae Plane Block Impact on Quality of Recovery After Lumbar Spinal Decompression
Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. The benefits of ESPB are not yet demonstrated.
- Trial name
- ESPB (NCT04943549)
- Testing
- Bupivacain
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University