Clinical trials: Lumbar Decompression, open to volunteers
Lumbar Canal Stenosis, Lumbar Spinal Stenosis
Is it Really Necessary Going All Over the Top in Patients With Symptomatic Lumbar Spinal Stenosis?
The goal of this clinical trial is to evaluate the theory of epidural pressure by comparing a surgical procedure that aims to perform less bone resection compared to conventional surgery in patients with lumbar spinal stenosis.
- Conditions
- Lumbar Canal Stenosis, Lumbar Spinal Stenosis, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07026305
- Testing
- Pressure-guided laminectomy (PGL), Laminectomy without pressure guidance (LWPG)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Seroma, Lumbar Spine Decompression
Management of Seroma After Posterior Lumbar Spine Decompression
The aim of this study is to evaluate the clinical presentation and management strategies of seroma formation following posterior lumbar spine decompression.
- Trial name
- NCT07060781
- Testing
- Posterior Lumbar Spine Decompression
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kafrelsheikh University
Spinal Stenosis Lumbar
Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis
Lumbar Spinal Stenosis (LSS) is a syndrome characterized by anatomical narrowing of the central canal, lateral recess, or intervertebral foramen of the lumbar spine, leading to compression of nerve roots, the cauda equina, and…
- Trial name
- NCT07482826
- Testing
- Full-Endoscopic Decompression, Endoscopic Lumbar Interbody Fusion
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Degenerative Lumbar Canal Stenosis
Comparison Between The Results of Open and Microsurgical Decompression in Degenerative Spinal Canal Stenosis in Lumbar Spine
To compare the outcomes of open and microsururgical decompression in degenerative spinal stenosis in lumbar spine
- Trial name
- NCT06722859
- Testing
- Open surgical decompression in degenerative lumbar canal stenosis, Microsurgical decompression
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Opioid Use, Lumbar Spinal Stenosis
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy.
- Conditions
- Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
- Trial name
- NCT05058287
- Testing
- Depo-Medrol 40Mg/Ml Suspension for Injection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hospital for Special Surgery, New York
Degeneration, Spinal Stenosis
Vertebropexy - Randomized-controlled Trial
To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)
- Conditions
- Degeneration, Spinal Stenosis, Fusion of Spine
- Trial name
- VPRCT (NCT06024785)
- Testing
- Vertebropexy
- Where
- Switzerland
- Volunteers
- 164 people
- Sponsor
- Balgrist University Hospital
Lumbar Spinal Stenosis
Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to conduct a multicenter comparison of the clinical efficacy of Endo-Surgi Plus endoscopic technique, UBE endoscopic technique, and microdiscectomy technique in the treatment of lumbar spinal…
- Trial name
- NCT06719037
- Testing
- Endo-Surgi Plus endoscopic surgery, Unilateral biportal endoscopic surgery, Microdiscectomy
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Qilu Hospital of Shandong University
Lumbar Spinal Stenosis
Endoscopic Decompression Versus Microscopic Decompression in Lumbar Canal Stenosis
To compare between the clinical and surgical efficacies of bi-portal endoscopic and microscopic decompressive laminectomy in patients with degenerative lumbar spinal stenosis.
- Trial name
- NCT06381167
- Testing
- Endoscopic Decompressive Laminectomy
- Volunteers
- 52 people
- Sponsor
- Assiut University
Lumbar Spinal Stenosis
Study Comparing Local/ MAC Anesthesia in Lumbar Decompression
Explore efficacy, complications, and other factors associated with anaesthetic choice- To evaluate the efficacy of local + MAC as an alternative anesthetic to general anesthesia and to analyze patients' outcomes and experiences.
- Trial name
- NCT04992572
- Testing
- Propofol Injection, Lidocaine Hydrochloride, Injectable
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
LUMBAR STENOSIS, Sagittal Imbalance
Spontaneous Correction of Sagittal Imbalance After Isolated Lumbar Decompression
Sagittal spinal imbalance may be caused by orthopedic problems, compression of the neural structures of the spinal canal, and pain syndrome (functional imbalance).
- Conditions
- LUMBAR STENOSIS, Sagittal Imbalance, Degeneration Lumbar Spine, Lumbar Decompression
- Trial name
- NCT07139938
- Testing
- Isolated lumbar decomression
- Where
- 3 sites in Russia
- Volunteers
- 165 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Adjacent Segment Disease
Decompression Versus Decompression and Fusion
Adjacent segment disease (ASD) in the lumbar spine is a well-known sequela of lumbar fusion surgery. The annual incidence of adjacent level re-operation is approximately 3% with a ten-year prevalence of 20-30%.
- Trial name
- NCT04542720
- Testing
- Observational: Decompression, Observational: Extension Fusion
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease
Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis
Comparing the functional and radiographic outcomes in surgical treatment in failed conservative treatment, single-level low grade degenerative lumbar spondylolisthesis between Minimal Invasive Surgery Transforaminal Lumbar…
- Conditions
- Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease, Lumbar Spinal Stenosis
- Trial name
- MIS-TLIF (NCT06749314)
- Testing
- Lumbar Endoscopic - Unilateral Laminotomy for Bilateral Decompression
- Where
- Thailand
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Spine Stenosis, Lumbar Spine Degeneration
OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Trial name
- NCT05452694
- Where
- 3 sites in United States
- Volunteers
- 235 people
- Sponsor
- OpalGenix, Inc
Complications, Postoperative
A Prospective, Randomized Comparison Of Drainage Techniques After One- Or Two-Level Open Posterior Lumbar Decompression Or Decompression And Fusion
This project is being done to understand if a drain reduces recovery problems after surgery, such as infection or the need for more surgery.
- Trial name
- NCT06820736
- Testing
- Drain
- Where
- United States
- Volunteers
- 975 people
- Sponsor
- Twin Cities Spine Center
Spinal Surgery for Lumbar Spinal Stenosis (LSS)
Activity Post Spinal Surgery Engagement Trial
Back pain can be disabling, limiting the ability to walk and to engage in physical activity. For patients with degenerative lumbar spinal stenosis, decompressive surgery often provides substantial pain relief and improved…
- Trial name
- ASSET (NCT07825480)
- Testing
- Wrist based activity tracker wear, Basic Study Activities, Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brigham and Women's Hospital
Lumbar Spinal Stenosis
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months…
- Trial name
- NCT03072927
- Testing
- MILD, Interspinous Process Decompression
- Where
- 2,393 sites in United States
- Volunteers
- 8,000 people
- Sponsor
- Stryker Instruments
Spinal Fusion, Chronic Lower Back Pain
Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery
After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating…
- Trial name
- NCT06282770
- Testing
- Laser Diode Brace
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Lumbar Degenerative Spondylolisthesis
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis.
- Trial name
- NCT07289737
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Lumbar Decompression
Ambulatory Geriatric Endoscopic Spine
The research focuses on evaluating the clinical outcomes of endoscopic lumbar decompression surgery performed in an outpatient setting for patients over 75 years old.
- Trial name
- AGES (NCT06523426)
- Testing
- Patient treated by spinal endoscopy
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Degenerative Lumbar Spinal Stenosis
Segmental Decompression Versus Wide Decompression With Fixation for Degenerative Lumbar Canal Stenosis
The purpose of this study is to compare two different surgical techniques for treating degenerative lumbar canal stenosis, a condition where the lower spinal canal narrows and puts pressure on the spinal nerves.
- Trial name
- NCT07542054
- Testing
- Segmental Decompression, Wide Decompression with Fixation
- Volunteers
- 56 people
- Sponsor
- Assiut University