Clinical trials: Lumbar Discectomy
Epidural Analgesics for Comparison
A Comparative Study Between Lumbar Epidural Analgesia Versus Local Infiltration Anesthesia Combined With Dexmedetomidine Intravenous Infusion in Endoscopic Lumbar Discectomy Surgeries: A Retrospective Study
The goal of this observational study is to compare the effectiveness and patient satisfaction of local anesthesia combined with intravenous Dexmedetomidine versus epidural anesthesia in endoscopic lumbar discectomy surgeries
- Trial name
- NCT07088016
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Lumbar Disc Disease
Injection of Autologous Bone Marrow Aspirate in Patients With Degenerative Disc Disease.
Lumbar discectomy and injection of purified cellular bone marrow concentrate or lumbar discectomy only
- Trial name
- NCT05146583
- Testing
- Autologous bone marrow aspirate injected intradiscal after microdiscectomy, Discectomy only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York Presbyterian Hospital
Lumbar Disc Herniation
Comparative Study Between UBE and PETD for the Treatment of Lumbar Spinal Canal Stenosis
OBJECTIVE Both unilateral biportal endoscopy technique(UBE) and percutaneous endoscopic transforaminal discectomy(PETD) are minimally invasive and effective surgical procedures for lumbar spinal stenosis.The object of this…
- Trial name
- NCT05033457
- Testing
- unilateral biportal endoscopy technique or percutaneous endoscopic transforaminal discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Endoscope, Open
Endoscopic Versus Open Lumbar Discectomy in Diabetic Patients
This study aims to compare the endoscopic versus open lumbar discectomy in diabetic patients.
- Conditions
- Endoscope, Open, Lumbar Discectomy, Diabetes Mellitus
- Trial name
- NCT07060846
- Testing
- Endoscopic lumbar discectomy, Open lumbar discectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Lumbar Herniated Disc
Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the effectiveness of two minimal invasive endoscopic discectomy, PTED and MED, for the treatment of symptomatic lumbar disc herniation.
- Trial name
- NCT01997086
- Testing
- Percutaneous transforaminal endoscopic discectomy (PTED), Microendoscopic discectomy (MED)
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Pain
Prospective, Randomized, Double Blind Study Comparing IV vs PO Acetaminophen in Patients Undergoing Lumbar Discectomy
Both intravenous and oral acetaminophen have been shown to reduce post-operative pain scores when given preoperatively. This study investigates if there is a difference between the intravenous and the oral forms when given…
- Trial name
- NCT02067442
- Testing
- oral acetaminophen, intravenous acetaminophen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Lumbar Osteoarthritis
Primary Osteoarthritis Lumbar Spine: Establishing Its Cause, Pathogenesis and Treatment.
The study was about a root cause of Primary Osteoarthritis Lumbar Spine producing disabilities in sitting, climbing and walking etc. In advance stage the person is bereft of his/her personal physical activities.
- Trial name
- NCT05693415
- Where
- 6 sites in India
- Volunteers
- 154 people
- Sponsor
- Knee Pain Clinic
Lumbar Disc Herniation
A Trial of Percutaneous Lumbar Discectomy Combined With Ozone for Treatment of LDH
Lumbar disc herniation (LDH) is a common pathological process leading to spinal surgery. Open discectomy used to be a widespread procedure for surgical treatment for symptomatic LDH.
- Trial name
- NCT02372032
- Testing
- percutaneous lumbar discectomy, ozone therapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhongda Hospital
Radiculopathy
Management of Lumbar Discectomy by Endoscopy and Conventional Microscopic Discectomy
Currently, microscopic discectomy is performed as a minimally invasive surgery, thus reducing impact of so-called conventional "open" discectomies.
- Trial name
- ENDOLOMB (NCT06193265)
- Testing
- Discectomy
- Where
- France
- Volunteers
- 539 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Disc, Herniated
Epiduroscopic Laser Discectomy Procedures
Epiduroscopy or spinal endoscopy is the imaging of the epidural space using a percutaneous and minimally invasive fiberoptic imaging device.
- Trial name
- NCT03319875
- Testing
- Epiduroscopic Laser Discectomy
- Volunteers
- 163 people
- Sponsor
- Sakarya University
Post Operative Sciatica by Lumbar Spinal Fibrosis
Lumbar Spinal Fibrosis and TNF Alpha Inhibition
TNF-alpha is the main cytokine implicated in the formation of lumbar spinal fibrosis. Inhibiting TNF-alpha could significantly decrease spinal fibrosis after lumbar discectomy.
- Trial name
- NCT00385086
- Testing
- TNF blocker
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Disc Disease
Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity
Focus of this study is evaluation of the outcome, neurologic impairment and safety of epidural steroide following lumbar discectomy for herniated disc disease.
- Trial name
- NCT01499641
- Testing
- Methylprednisolone
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Lumbar Disc Herniation
Percutaneous Discectomy to Treat Symptomatic Lumbar Disc Herniation : Evaluation of Clinical Efficiency, Patient Reported Outcomes and Economical Impact by Assessing Time Before Return to Work and Duration of Hospitalization Stay
This study aims to evaluate the clinical (pain) and functional (patient reported outcomes) efficacy of percutaneous discectomies under CT guidance to treat lumbar disc herniations resistant to conservative treatment and nerve…
- Trial name
- NCT05772143
- Testing
- Percutaneous discectomies under CT
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Lumbar Spinal Stenosis
Comparision of Endoscopic Discectomy and Microdiscectomy for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to conduct a multicenter comparison of the clinical efficacy of Endo-Surgi Plus endoscopic technique, UBE endoscopic technique, and microdiscectomy technique in the treatment of lumbar spinal…
- Trial name
- NCT06719037
- Testing
- Endo-Surgi Plus endoscopic surgery, Unilateral biportal endoscopic surgery, Microdiscectomy
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Qilu Hospital of Shandong University
Postoperative Pain, Lumbar Disc Herniation
Comparison of Quadro Iliac vs Erector Spinae Plane Block on Postoperative Pain and Opioid Use in Lumbar Discectomies
This multicenter, randomized, controlled study aims to compare the analgesic efficacy of Quadro Iliac Plane Block (QIPB) and Erector Spinae Plane (ESP) Block in lumbar vertebra surgeries.
- Trial name
- NCT06656507
- Testing
- Quadro Iliac Plane Block (QIPB), Erector Spinae Plane Block (ESP)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Lumbar Disc Herniation
Microendoscopic Lumbar Discectomy: A Study of 100 Cases
Evaluate the outcome of micro endoscopic discectomy (MED) by tubular retractors on safety and efficacy of the technique.
- Trial name
- NCT03359564
- Testing
- micro endoscopic discectomy
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Lumbar Disc Surgery, Motivational Interviewing
The Effect of Motivational Interviewing on Patients With Lumbar Discectomy
Abstract Objective: The aim of the study was to determine the effect of motivational interviewing about adaptation to body mechanics on the level of disability due to low back pain and quality of life in patients with lumbar…
- Conditions
- Lumbar Disc Surgery, Motivational Interviewing, Nursing Care
- Trial name
- NCT07169955
- Testing
- Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gazi University
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital