Clinical trials: Lumbar Disk Surgery
Lumbar Disc Herniation, Radiculopathy
Rehabilitation Following Lumbar Disc Surgery
The proposed study will be a randomized clinical trial designed to determine the most effective physical therapy program for individuals who have undergone lumbar discectomy surgery.
- Trial name
- NCT00894972
- Testing
- Rehabilitation following lumbar disc surgery (discectomy)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient
Directed Imagery Technique Applied to Patients Undergoing Lumbar Disc Herniation Surgery
The Directed Imagery technique (YIT) is a set of stories that people create by first giving relaxation exercises and then visualizing the symbols given by the practitioner.
- Conditions
- Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient, Nurse-Patient Relations
- Trial name
- NCT05283291
- Testing
- Directed Imagery Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Degenerative Disc Disease, Spondylolisthesis, Lumbar Region
Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions
Spinal operations including lumbar fusions for degenerative disorders are becoming more prevalent as the population ages. Inadequate or excessive postoperative analgesia can result in medical comorbidities and prolonged hospital…
- Trial name
- NCT04112550
- Testing
- Methadone Hydrochloride, Oxycodone-Acetaminophen
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Endoscopic Spinal Surgery
Application of 3D printing guide plate in endoscopic spinal surgery
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radicular Pain, Low Back Pain
- Trial name
- NCT05632835
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation Surgery, Disc Herniation
Return to Activity After Surgery for Lumbar Disc Herniation
RCT investigating postoperative activity restriction after lumbar discectomy in patients treated with annular closure.
- Trial name
- NCT07667348
- Testing
- Postoperative therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intrinsic Therapeutics
Degenerative Lumbar Disc Disease, Spondylolisthesis
Spine Fusion Instrumented With BMP-2 vs Uninstrumented With Infuse BMP-2 Alone
The goal of spinal fusion is to relieve pain and/or increase stability in painful or unstable spine joints. A patient may or may not receive rods and screws with the use of bone graft materials to facilitate bone growth and a…
- Conditions
- Degenerative Lumbar Disc Disease, Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT00405600
- Testing
- Device used in surgery with or without instrumentation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Lumbar Herniated Disc
The Effect of Ozone Therapy for Lumbar Herniated Disc
The purpose of this study is to assess the efficacy (vs. placebo) of ozone infiltration and its effectiveness in comparison with micro discectomy in the treatment of lumbar herniated disc with criteria for surgery.
- Trial name
- NCT00566007
- Testing
- Discectomy/ micro discectomy, Ozone therapy, Oxygen therapy
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Kovacs Foundation
Postoperative Delirium, Pain, Postoperative
Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery
The proposed intervention will examine two alternative methods for postoperative pain control. Two treatment arms of this study will include subjects who receive an erector spinae block (ESP) after induction of anesthesia but…
- Conditions
- Postoperative Delirium, Pain, Postoperative, Degenerative Disc Disease
- Trial name
- NCT06199999
- Testing
- Erector Spinae Block, Local infiltration with local anesthetic
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Rashmi Mueller
Disc Degeneration
Comparaison of Interbody Bone Fusion Between Two Osteoinductive Bioactive Bone Substitutes After Anterior Lumbar Interbody Arthrodesis in Degenerative Lumbar Disc Surgery in Adults
Disc degeneration is a progressive deterioration process of the intervertebral disc, which can manifest as significant low back pain and a loss of mobility that interferes with daily activities.
- Trial name
- FUSALIF (NCT07044206)
- Testing
- Use of bone substitute during intervertebral fusion surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit
Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime
The Viper Prime/Expedium spine systems are intended to provide immobilization and stabilization of spinal segments in skeletally mature patients as an adjunct to fusion in the treatment of acute and chronic instabilities or…
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Trial name
- NCT06704906
- Testing
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nitin Agarwal
Degenerative Disc Disease Lumbar, Spinal Stenosis
Multimodal Analgesia Versus Routine Care Pain Management
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization.
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- MMA (NCT01861743)
- Testing
- Multimodal Analgesia, Patient controlled analgesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery
Introduction: Improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spine Instability
- Trial name
- NCT05871073
- Testing
- Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital Fattouma Bourguiba
Lumbar Disc Surgery
Comparing The Effect of Adding Dexmedetomidine to Bupivacaine in Classical and Modified Thoracolumbar Interfascial Plane Block on Postoperative Pain in Patients Undergoing Lumbar Disc Surgeries
Spinal surgeries are frequently conducted to stabilize the vertebrae and discs of the spine. These surgeries typically require substantial manipulation of subcutaneous tissues, bones, and ligaments .
- Trial name
- NCT06690021
- Testing
- Dexmedetomidine
- Volunteers
- 26 people
- Sponsor
- Assiut University
Lumbar Disc Herniation
A Comparison Between Biportal and Uniportal Endoscopic Lumbar Discectomy
This study aims to provide a detailed comparison between different methods of lumbar discectomy by the use of different types of spine endoscopy to evaluate the benefits and drawbacks of each type
- Trial name
- NCT07151651
- Testing
- Endoscopic lumbar discectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Research on Key Technology Development and Clinical Application of Small Interactive Spinal Endoscopic Surgery Robot
The aim of the study was to investigate the correlation between the extent of decompression and patient follow-up metrics at 1 year postoperatively by analysing data from a real-world, multicentre cohort of patients, and to…
- Trial name
- NCT06480214
- Testing
- endoscopic spine surgery
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Jishuitan Hospital
Lumbar Disc Herniation
The Effect of Progressive Relaxation Exercise on Pain and Kinesiophobia After Lumbar Disc Herniation Surgery
We aimed to assess the influence of progressive muscle relaxation exercise on kinesiophobia and pain during after lumbar disc surgery using the Visual Analog Scale (VAS) and the Tampa Kinesiophobia Scale in a prospective…
- Trial name
- NCT05288634
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Scarring, Spinal Stenosis
dHACM in Lumbar Decompression and Microdiscectomy Surgery
Prospective evaluation of the safety and efficacy of dHACM on clinical outcomes in lumbar laminectomy and microdiscectomy patients as assessed by Oswestry Disability Index.
- Conditions
- Scarring, Spinal Stenosis, Herniated Disc
- Trial name
- NCT02300909
- Testing
- Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- MiMedx Group, Inc.
Lumbar Disc Herniation
Telerehabilitation After Lumbar Disc Herniation Surgery
This randomized controlled trial evaluated the effectiveness of a telerehabilitation-based exercise program in individuals who had undergone surgery for lumbar disc herniation.
- Trial name
- NCT07889817
- Testing
- Home Exercise Program, Telerehabilitation-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Hasan Kalyoncu University
Postoperative Pain
Erector Spinae Plane Block For Lumbar Disc Hernia Repair
Pain management after lomber disc hernia repair surgery is a challenging issue for anesthetists. Erector Spinae plane block is a novel analgesic technique which could be used for this purpose.
- Trial name
- NCT03744689
- Testing
- Erector Spinae Plane block, Bupivacaine Hydrochloride, PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Lumbar Disc Herniation, Radiculopathy Lumbar
Quantitative Sensory Testing and PET/CT Scanning in Assessment of Surgical Outcome for Lumbar Disc Herniation
Patients with lumbar disc herniation suffer from pain and morbidity. Surgical intervention can be a quick and effective relief, however some individuals experience less favorable outcome.
- Trial name
- PET-Pain (NCT03894943)
- Testing
- PET/CT scan, Quantitative Sensory Testing
- Volunteers
- 61 people
- Sponsor
- Spine Centre of Southern Denmark