Clinical trials: Lumbar Laminectomy
Lumbar Spinal Stenosis
Microdecompression Versus Open Laminectomy and Posterior Stabilization for Multilevel Lumbar Spine Stenosis
This study compare the results of 2 methods in surgical treatment of Lumbar spine stenosis.These are microdecompresssion and open decompression with posterior stabilization.
- Trial name
- NCT04087694
- Testing
- Microdecompression
- Volunteers
- 100 people
- Sponsor
- Hawler Medical University
Herniated Disk Lumbar
Evaluation of Plenum® Tissue Ortho to Prevent Epidural Fibrosis and Post-laminectomy Syndrome.
The goal of this clinical trial is to compare if adding a polydioxanone membrane prevents epidural fibrosis and, consequently, the rate of occurrence of the post-laminectomy syndrome in participants undergoing microdiscectomy for…
- Trial name
- NCT05776628
- Testing
- Plenum® Tissue ortho membrane (polydioxanone membrane)
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- M3 Health
Postoperative Pain
Erector Spinae Plane Block Impact on Quality of Recovery After Lumbar Spinal Decompression
Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. The benefits of ESPB are not yet demonstrated.
- Trial name
- ESPB (NCT04943549)
- Testing
- Bupivacain
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Pseudarthrosis After Fusion or Arthrodesis
Collecting Bone Graft During Spinal Decompression and Posterolateral Lumbar Fusion to Better Define Bone Making Cells
The purpose of this study is to improve fusion (bony healing) techniques and improve patient recovery by identifying cells in your body that make bone.
- Trial name
- NCT01409954
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis
SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion
The purpose of the project is to perform an RCT comparing patient satisfaction and outcome with or without the use of an expert panel.
- Conditions
- Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
- Trial name
- SLIPII (NCT03570801)
- Testing
- Expert Panel Review
- Where
- 17 sites in United States, Canada
- Volunteers
- 662 people
- Sponsor
- Lahey Clinic
Lumbar Radiculopathy
Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa In Patients Of Lumbar Radiculopathy
To compare the effects of high intensity spinal decompression exercises and Eldoa on pain, ROM and Disability in patients of lumbar radiculopathy.
- Trial name
- NCT06087107
- Testing
- High Intensity Spinal Decompression Exercises, Eldoa
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Lumbar Disc Herniation
Comparison of Ultrasound-Guided Classic And Lateral Approach Thoracolumbar Interfascial Plane Block
US-guided peripheral nerve blocks have been used increasingly due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT03854240
- Testing
- Classic block (Group C) and modified block (Group M) groups
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Spinal Instability
CLUBE (UBE Stability / Dynamic Radio)
Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue.
- Trial name
- NCT06904326
- Testing
- Postoperative dynamic radiography
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinique Saint Jean, France
Discogenic Low Back Pain
McKenzie Extension Protocol Versus Core Stability Exercises Combined With Spinal Decompression in Discogenic Lumbar Radiculopathy
The pathophysiology arises from structural and biochemical degeneration within the intervertebral disc rather than direct nerve root compression alone.
- Trial name
- D-MECS (NCT07730502)
- Testing
- McKenzie Extension Protocol, Core stability Exercise, Spinal decompression, Moist heat, interferential current
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Lumbar Spinal Stenosis
Endoscopic Versus Conventional Lumbar Decompression for Lumbar Canal Stenosis
This is a randomized controlled trial comparing interlaminar uniportal endoscopic bilateral lumbar decompression with conventional open laminectomy in patients with degenerative lumbar canal stenosis.
- Trial name
- ENDOLSS (NCT07562035)
- Testing
- Interlaminar Uniportal Endoscopic Lumbar Decompression, Open Lumbar Laminectomy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Pain, Spine Fusion
Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP
Single-center, randomized study will enroll 50 subjects who are scheduled for 1-3 level posterior laminectomy \& fusion. Study participants who are eligible for the posterior lumbar laminectomy and fusion procedure will be…
- Trial name
- NCT06154980
- Testing
- Preoperative Ultrasound TLIP, Intraoperative TLIP
- Where
- United States
- Sponsor
- Corewell Health East
Lumbar Spinal Stenosis
Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis
Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking.
- Trial name
- NCT07281625
- Testing
- Decompressive Laminectomy, Decompressive Laminectomy With Transpedicular Screw Fixation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Punjab Health Care Commission
Tumor of Spinal Cord
Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection
Objective to construct the related early activity program for patients with lumbar intraspinal tumor after hemilaminectomy, and evaluate the postoperative limb function exercise according to the content of the program.
- Trial name
- NCT04968730
- Testing
- Postoperative rehabilitation nursing
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Degenerative Lumbar Spinal Stenosis
Biportal Endoscopy Spine Surgery (BESS )Versus Unilateral Laminotomy Bilateral Decompression (ULBD ): RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic decompression and the unilateral approach bilateral decompression in spinal stenosis
- Trial name
- NCT03302507
- Testing
- BESS, ULBD
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Lumbar Disc Herniation, Spinal Disk Injury
Decompression With ELDOA on Lumbar Disc Protrusion Patient
Decompression therapy is a result-oriented approach but it expensive and minimum availability in Pakistan. In physical therapy, we use different exercises to solve multiple spine problems.
- Conditions
- Lumbar Disc Herniation, Spinal Disk Injury, Protrusion
- Trial name
- NCT04760210
- Testing
- Control Group, Decompression Group, ELDOA
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Lumbar Radiculopathy
Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes
This randomized control trial will compare opioid use, pain, and functional outcomes following decompression surgery for single-level lumbar radiculopathy in patients who undergo placement of corticosteroid epidural injection…
- Trial name
- NCT03543033
- Testing
- Corticosteroid injection
- Where
- United States
- Sponsor
- Lahey Clinic
Failed Back Surgery Syndrome, Postlaminectomy Syndrome
Low-Dose Radiation to Prevent Complications of Back Surgery
More than 10,000 people each year in the United States have "failed back surgery syndrome" caused by scars that form around the outer surface of the spinal cord.
- Conditions
- Failed Back Surgery Syndrome, Postlaminectomy Syndrome, Postdiscectomy Epidural Fibrosis
- Trial name
- NCT00018876
- Testing
- Lumbar nerve root decompression, Preoperative low-dose external beam radiation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Pittsburgh
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center