Clinical trials: Lumbar Pain
Discogenic Pain, Low Back Pain
Intradiscal Platelet Rich Plasma
To assess changes in pain and function in patients with discogenic low back pain after a standard of care intradiscal injection of Platelet-Rich Plasma (PRP).
- Conditions
- Discogenic Pain, Low Back Pain, Chronic Pain
- Trial name
- NCT04544709
- Testing
- Low back intradiscal injection of platelet rich plasma (PRP)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Chronic Low Back Pain
Patient Engagement Via Crowdsourcing
The study aims to advance pain research by exploring feasibility of crowdsourcing patient pain data via Amazon Mechanical Turk, the largest and most studied crowdsourcing platform in the U.S.
- Trial name
- PECS (NCT03264521)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 8,193 people, healthy volunteers welcome
- Sponsor
- RAND
Chronic Low-back Pain
Brain Effects of Opiate Agonist and Antagonist
This study will look at the short-term effect of morphine on brain response to food.
- Trial name
- NCT04342130
- Testing
- Morphine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Muscle Spasm; Back Pain
Evaluation of Eperisone HCl in the Treatment of Acute Musculoskeletal Spasm Associated With Low Back Pain - A Double Blind, Randomised, Placebo Controlled Clinical Trial
The purpose of this study is to evaluate the efficacy of Eperisone HCl in the treatment of Acute Musculoskeletal spasm associated with Low-Back Pain.
- Trial name
- NCT00327730
- Testing
- Eperisone
- Where
- 4 sites in India
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Low Back Pain, Chronic Low Back Pain (CLBP)
Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain
The goal of this clinical trial is to learn whether the Spinery® RF Generator and its sterile single-use accessories can safely lower disability and pain in adults with long-term low back pain that is thought to come from changes…
- Trial name
- BASILEA (NCT07696507)
- Testing
- Single Bipolar Ablation, Double Parallel Bipolar Ablation, Double Cross Bipolar Ablation
- Where
- 3 sites in Italy
- Volunteers
- 69 people
- Sponsor
- Axon srl
Chronic Low Back Pain
A Pilot Trial of IV Pamidronate for Low Back Pain
INTRODUCTION Pamidronate and other bisphosphonates (bisph) have an anti-nociceptive effect in animals. In humans, IV pamidronate is analgesic in patients affected by numerous painful conditions, including cancer bone pain…
- Trial name
- NCT01210599
- Testing
- Pamidronate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pappagallo, Marco, M.D.
Acute Lower Back Pain
Comparative Clinical Trial: Manual Therapy With and Without Radial Extracorporeal Shockwave Therapy to Treat Acute Low Back Pain
The goal of this clinical trial is to learn if the addition of radial pulse therapy to chiropractic care will help adult patients recover faster to an acute bout of low back pain.
- Trial name
- NCT06852898
- Testing
- Chiropractic Care, Radial Extracorporeal Shockwave Therapy (ESWT) - Radial Pulse Therapy
- Where
- United States
- Sponsor
- Northeast College of Health Sciences
Low Back Pain
Postural Re-education in Low Back Pain
The Global Postural Re-Education is a global approach for the treatment of musculoskeletal disease. Using specific progressive posture for stretching particular shortened chain muscle the method wants to equilibrate the…
- Trial name
- NCT00789204
- Testing
- Global Postural Re-education, Standard Exercise Training
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bologna
Chronic Low Back Pain
Erector Spinae Plane Block With or Without Thoracolumbar Fascia Injection for Chronic Low Back Pain
This study aims to investigate whether adding a thoracolumbar fascia (TLF) interfascial injection to an erector spinae plane (ESP) block improves pain relief and functional outcomes in patients with chronic axial low back pain.
- Trial name
- ESP-TLF (NCT07900347)
- Testing
- Ultrasound-Guided ESP Block, Thoracolumbar Fascia Interfascial Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Damla Yürük
Lumbar Disc Disease
Erector Spinae Plane Block in Spine Surgeries
Aim of this study was to assess the efficacy of erector spinae plane block (ESB) for postoperative pain management in lumbar spine surgery.
- Trial name
- ESB (NCT05247021)
- Testing
- erector spinae block for group E
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Low Back Pain, Neck Pain
Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy
Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care.
- Conditions
- Low Back Pain, Neck Pain, Radiculopathy
- Trial name
- NCT07733752
- Testing
- re-visit AI symptom-checker use
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Low Back Pain, Pelvic Pain
Virtual Reality to Improve Low-back Pain and Pelvic Pain During Pregnancy
A large percentage of women suffer low back and pelvic pain both during and after pregnancy. There are several factors to which these complaints are attributed, even affecting their daily lives.
- Trial name
- NCT05571358
- Testing
- Virtual Reality (Nature Trek)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Low Back Pain
Bowen's Technique and Muscle Energy Technique on Hamstrings Tightness
The aim of this research is to find and compare the effect of Bowen's technique and Muscle energy technique on intensity of pain, active knee extension, limited forward bending and active straight leg raise on hamstrings…
- Trial name
- NCT04745858
- Testing
- Bowen's Technique, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
Tolerability, Safety and Pharmacokinetics of a Topical AB001 Patch in Healthy Subjects
The study evaluates the safety, tolerability and pharmacokinetics of single and repeated doses of topical AB001 patch and the bioavailability relative to the oral capsule and topical positive comparative patch.
- Trial name
- NCT03997734
- Testing
- AB001, oral capsule, positive comparative patch
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Low Back Pain
Identification of Risk Factors for Recurrence of Low Back Pain and Occupational Repercussions
Low back pain (LBP) is the leading cause of disability and one of the most common reasons for physician visits in primary care, with a 33 % rate of recurrence during the first year, converting LBP into a chronic condition.
- Trial name
- LORET (NCT05286333)
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Fondation Ildys
Chronic Low Back Pain
Single Session Pain Psychology Treatment: Comparative Efficacy & Mechanisms
This study aims to compare the efficacy of a single session psychological treatment, "Empowered Relief" (ER), with the current standard of care, group Cognitive Behavioral Therapy (CBT) specifically on individuals with chronic…
- Trial name
- NCT03167086
- Testing
- "Empowered Relief" (ER), Cognitive Behavioral Therapy (CBT), Health Education (HE)
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Stanford University
Low Back Pain, Chronic
A Combined Exercise Programme Involving Strengthening, Flexibility and Aerobic Exercise for Lower Back Pain
This randomised controlled trial will evaluate the effectiveness of different exercise modalities for individuals with low back pain.
- Trial name
- NCT06921694
- Testing
- Runner group, Swim/Cycle Group
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Low Back Pain
Efficacy and Safety of NVP-1203 and NVP-1203-R in Patients With Acute Low Back Pain
The purpose of this study is to evaluate the efficacy and safety NVP-1203 in patients with acute low back pain.
- Trial name
- NCT04082975
- Testing
- NVP-1203, NVP-1203-R
- Where
- South Korea
- Volunteers
- 421 people
- Sponsor
- NVP Healthcare
Low Back Pain
Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain
The purpose of this study is to evaluate efficacy, tolerability and safety of Etoreat®(Etodolac-Lidocaine Topical Patch) in the treatment of acute low back pain (LBP).
- Trial name
- NCT01968005
- Testing
- Etoreat®(Etodolac-Lidocaine Topical Patch)
- Where
- 7 sites in United States
- Volunteers
- 232 people
- Sponsor
- MEDRx USA, Inc.
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