Clinical trials: Lumbar Pain
Low Back Pain, Lumbar Spinal Fusion
Back to Life - Early Rehabilitation Therapy for Patients Undergoing Lumbar Spinal Fusion
Aim This study aims to assess the effectiveness of an early intervention comprising individually tailored physiotherapy, including dialogue, education, and graded activity, following lumbar spinal fusion surgery.
- Trial name
- Back to Life (NCT07378735)
- Testing
- SOGA - Socratic dialogue and Graded Activity, SOGA - SOcratic dialougue and Graded-Activity, SOGA - SOcratic dialogue and Graded-Activity
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Low Back Pain (CLBP), Lumbar Spondylosis
Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain.
Chronic low back pain (CLBP) due to lumbar spondylosis is a leading cause of disability, significantly impacting the quality of life in middle-aged and elderly populations.
- Trial name
- NCT07530042
- Testing
- Electroacupuncture, Auricular Acupressure
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Lumbar Spine Surgery, Chronic Low-back Pain
Telehealth Mindfulness After Spine Surgery
The goal of this pilot clinical trial is to compare two behavioral interventions for patients who are recovering from lumbar spinal surgery for a degenerative spine condition. The study aims to answer the following questions: 1.
- Conditions
- Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
- Trial name
- NCT05698914
- Testing
- Telehealth mindfulness-based intervention (MBI), Telehealth Education
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Back Pain Lower Back, Neck Pain
Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)
This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between…
- Conditions
- Back Pain Lower Back, Neck Pain, Radiculopathy Multiple Sites, Spinal Stenosis Cervicothoracic Region
- Trial name
- CORTISS (NCT07762170)
- Testing
- triamcinolone acetonide (Kenalog), Celestone Soluspan 6Mg/Ml Suspension for Injection, Depo-Medrol 40Mg/Ml Suspension for Injection
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Igor Wilderman. MD
Lumbar Radiculopathy, Sciatica
Dose Dependent Steroid Injections
This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and…
- Conditions
- Lumbar Radiculopathy, Sciatica, Back Pain With Radiation
- Trial name
- NCT07494136
- Testing
- Triamcinolone 10 Mg/mL Injectable Suspension, Triamcinolone 40 Mg/mL Injectable Suspension, Triamcinolone 80 Mg/mL Injectable Suspension
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Patients Undergoing a Lumbar Slipped Disc Surgery
Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery
The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination…
- Trial name
- DEXA-PG-HD (NCT01811251)
- Testing
- Pregabaline (150mg), Dexamethasone (20mg/5ml; 0.2mg/kg)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion
NSAIDS Following Elective Lumbar Spine Fusion
This study will compare two common approaches to pain control after lumbar spinal fusion surgery. Participants will be randomly assigned to receive either standard pain medication alone or standard pain medication plus a short…
- Conditions
- NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion, Ketorolac, Postoperative Pain
- Trial name
- NCT07743606
- Testing
- Ketorolac, Naproxen, Standard Postoperative Pain Management
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Degenerative Disc Disease, DDD
Biologic Injection For Adults With Lumbar Disc Herniation
The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar
- Trial name
- BMAC (NCT07386548)
- Testing
- Bone Marrow Aspirate Concentrate (BMAC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Weill Medical College of Cornell University
Lumbar Microdiscectomy, Nerve Block
Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery
Lumbar microdiscectomy is a commonly used surgical procedure for treating herniated discs. Effective postoperative analgesia is crucial for early mobilization and functional recovery.
- Trial name
- NCT06851533
- Testing
- Standard Analgesia (No Block), Thoracolumbar Interfascial Plane (TLIP) Block, Quadro Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Back Pain Without Radiation, Low Back Pain
Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy
Low back pain is a leading cause of disability worldwide. The lumbar zygapophyseal joints (z-joints) are estimated to be the source of low back pain between 10% and 40% of the time.
- Conditions
- Back Pain Without Radiation, Low Back Pain, Lumbar Radiofrequency Neurotomy
- Trial name
- NCT03912519
- Testing
- Parallel placement of 16 gauge electrodes, Perpendicular placement with 22 gauge electrodes
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Vanderbilt University Medical Center
Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain
SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients
SPINE-RISK VE is a prospective multicenter cohort study designed to develop and internally validate a multimodal preoperative predictive model for Failed Back Surgery Syndrome (FBSS), now classified as Persistent Spinal Pain…
- Conditions
- Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine, Chronic Low Back Pain, Postoperative Pain, Lumbar Spine Surgery
- Trial name
- SPINE-RISK VE (NCT07693517)
- Testing
- SPINE-RISK VE multimodal preoperative assessment
- Where
- Venezuela
- Volunteers
- 150 people
- Sponsor
- juan jose valero quintero,MD
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Facet-Mediated Low Back Pain, Lumbar Facet Joint Osteoarthritis
Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy
The purpose of this research study is to evaluate the safety and effect of bone marrow-derived stem cells for the treatment of low back pain.
- Trial name
- CELLKINE II (NCT06001853)
- Testing
- BM-MSC injection, DSMO Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Lumbar Disc Herniation, Mindfulness Meditation
Mindfulness-based Psychoeducation in Patients With Lumbar Disc Herniation
This study aimed to investigate the effect of mindfulness-based psychoeducation on mindfulness, automatic thoughts, and pain beliefs in patients with lumbar disc herniation.
- Trial name
- MBPE (NCT07683884)
- Testing
- Experimental Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Giresun University
Spinal Stenosis Lumbar
Coflex PS3 Actual Conditions for Use Study
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA…
- Trial name
- PAS003 (NCT02555280)
- Testing
- coflex® Interlaminar Technology, Decompression
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Companion Spine, LLC