Clinical trials: Lumbar Pain
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome
Efficacy of Pregabalin in Patients With Radicular Pain
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
- Conditions
- Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome, Spinal Stenosis, Herniated Disc
- Trial name
- NCT00908375
- Testing
- Pregabalin, Sugar Pill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Northwestern University
Low Back Pain, Pain
D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of D-cycloserine versus placebo in relieving the signs and symptoms of patients with chronic lower back pain.
- Trial name
- NCT03535688
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Northwestern University
Chronic Nonspecific Low Back Pain
Effects of SIS Therapy in Individuals With Chronic Nonspecific Low Back Pain
Brief Summary - buraya yapıştırın Chronic nonspecific low back pain is a common condition that can cause pain, limitations in daily activities, and reduced quality of life.
- Trial name
- NCT07839169
- Testing
- SIS Therapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Back Pain, Low, Degenerative Disc Disease
Protocol for an Analytical Study With Microbiological, Phenotypic, Genotypic and Multiomics Techniques
The study aims to identify metabolites present in intervertebral discs colonized by C. acnes from patients with low back pain and degenerative disc disease, correlating them with their clinical, radiological and demographic…
- Trial name
- NCT05090553
- Testing
- Lumbar Spinal Fusion Surgery, Bacterial culture, Phenotypic and genotypic characterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Gaffree & Guinle Universitary Hospital
Chronic Pain, Low Back Pain
Searching for the Optimal tDCS Target Combined With Peripheral Electrical Stimulation in Chronic Low Back Pain
Low back pain (LBP) has been associated with severe impairments, primarily related to activities of daily living, functional ability and quality of life.
- Trial name
- NCT04496661
- Testing
- Transcranial Direct Current Stimulation on M1 and Peripheral Electrical Stimulation, Transcranial Direct Current Stimulation on DLPFC and Peripheral Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Lumbar Disc Herniation
Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine
This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.
- Trial name
- NCT03236753
- Testing
- Thread-embedding Acupuncture (TEA)
- Where
- 4 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Kyunghee University Medical Center
Low Back Pain
Effects of a Mat Pilates Exercise Program on Elderly Women With Chronic Nonspecific Low Back Pain
The technique of Pilates exercises on a mat has proven to be effective and practically applicable to patients with chronic back pain. However, its application in women over 65 years has not been adequately studied.
- Trial name
- NCT04752579
- Testing
- Pilates exercise program
- Where
- Greece
- Volunteers
- 63 people
- Sponsor
- Aristotle University Of Thessaloniki
Post-Operative Pain, Lumbar Laminectomy
HTX-011 in Spinal Surgery
This is a Phase 2, multicenter study in subjects undergoing an open lumbar decompression surgery.
- Trial name
- NCT04911062
- Testing
- Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator
- Where
- 12 sites in United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Low Back Pain
Relaxation Exercises for Low Back Pain and Insomnia in the Third Trimester of Pregnancy
The role of progressive muscle exercises has been widely explored. However, limited studies report its effectiveness in pregnant women in their third trimester suffering from pain and insomnia that may or may not be due to that…
- Trial name
- NCT05475327
- Testing
- Conventional Physical Therapy, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Chronic Low Back Pain (CLBP)
Art Therapy for Adults With Chronic Low Back Pain
This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).
- Trial name
- NCT07141069
- Testing
- Art therapy combined with Exercise, Exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Low Back Pain
Study of the Efficacy of Manual Therapy for a Subgroup of Acute Non-specific Low Back Pain
The purpose of this study is: To validate or not the interest of the classification using the pragmatic application of clinical predictive rule for low back pain to identify patients with good prognosis following a brief spinal…
- Trial name
- NCT01801553
- Testing
- Spinal manipulation, Usual medical care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Overweight or Obesity, Chronic Low-back Pain
Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Chronic low back pain (CLBP) is the most expensive cause of workrelated disability: it causes the highest number of years lived with disability.
- Trial name
- BO2WL (NCT05811624)
- Testing
- Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy., Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
- Where
- 2 sites in Belgium, Switzerland
- Volunteers
- 252 people
- Sponsor
- Vrije Universiteit Brussel
Spondylosis Lumbar
Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine Osteoarthritis
Chronic low back pain due to lumbar spine osteoarthritis is a common and disabling condition. Many patients do not get enough relief from standard treatments.
- Trial name
- NCT06874959
- Testing
- Battlefield Acupuncture (BFA), Electroacupuncture, Paracetamol 500 mg (as-needed)
- Where
- 2 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- Bui Pham Minh Man
Low Back Pain
Telehealth Physical Therapy for Chronic Back Pain - Ancillary Study to NCT03859713
This study evaluated the feasibility of an 8-week physical therapy program for persons with chronic low back pain provided entirely using telehealth with real-time, interactive video sessions with a physical therapist.
- Trial name
- TeleOPT (NCT05103462)
- Testing
- Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of Utah
Chronic Low Back Pain
MBM and taVNS for Low Back Pain and Depressive Symptoms
This two-arm randomized controlled trial aims to test the preliminary effect of home-based mindfulness-based meditation and transcutaneous auricular vagus nerve stimulation on managing pain and depressive symptoms among…
- Trial name
- NCT07415941
- Testing
- MBM, VNSM
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Florida State University
Low Back Pain
Thoraco-Lumbar Fascia Mobility
The purpose of the Thoraco-Lumbar Fascial Mobility (TLFM) study is to use ultrasound to measure the movement of connective tissue in the low back area of individuals with chronic low back pain (lasting more than 1 year).
- Trial name
- TLFM (NCT03916705)
- Testing
- High Velocity Low amplitude spinal manipulation (HVLA-SM)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic
Pain Measurement
Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints
The emotion Egg, or "eEgg" for short, is a sample series of a device for testing a new pain measurement method that is not yet on the market.
- Trial name
- SMeEgg (NCT05881551)
- Testing
- eEgg, NRS
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University of Witten/Herdecke
Regional Anesthesia, Pediatric Anesthesia
Continous Lumbar Plexus Block in Children
Randomised controlled prospective trial with 2 groups (active group with Lumbar plexus block (LPB)-catheter vs control group). In a randomized controlled trial, the investigators will investigate under controlled circumstances…
- Conditions
- Regional Anesthesia, Pediatric Anesthesia, Pain, Postoperative
- Trial name
- NCT03450096
- Testing
- LPB
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Low-back Pain, Neck Pain
Turkish Version of Revised Neurophysiology of Pain Questionnaire
The Neurophysiology of Pain Questionnaire was first developed in English to test whether healthcare staff and patients could exactly understand pain neurophysiology.
- Trial name
- NCT04099160
- Testing
- Evaluation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 182 people
- Sponsor
- Akdeniz University
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