Clinical trials: Lumbar Pain
Chronic Low Back Pain
CLBP Single-Arm Long-Term Follow-up Study
This is a prospective, noninterventional, observational post market data collection of long-term effectiveness and satisfaction outcomes for "A Prospective, Open-Label, Single-Arm Study of Intraosseous Basivertebral Nerve…
- Trial name
- NCT05207813
- Testing
- Intracept Procedure
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Boston Scientific Corporation
Chronic Non-specific Low Back Pain
Comparison of the Effectiveness of Myofascial Release Technique and Pilates Exercises in Chronic Non-Specific Low Back Pain
Objective: To evaluate the effectiveness of adding Myofascial Release Technique (MRT) to Clinical Pilates in adults with chronic non-specific low back pain (CNSLBP).
- Trial name
- NCT07551323
- Testing
- Myofascial Release Technique (MRT), Clinical Pilates Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
Postoperative Pain
Open-Label Placebo Treatment for Acute Postoperative Pain
This study is to evaluate whether the amount of morphine intake in acute postoperative pain following minimally invasive Transforaminal Lumbar Interbody Fusion (TLIF) can be decreased with an Open-Label Placebo (OLP) intervention…
- Trial name
- OLP-POP (NCT04339023)
- Testing
- treatment as usual
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Low Back Pain
Epigenetic and Molecular Biomarkers in Chronic Low Back Pain and Modic Changes
In the present study the investigators aim to examine the presence of bacteria in the disc and Modic Changes (MCs) (bone). A prospective study with 1-year follow-up of two patient populations undergoing elective spinal surgery…
- Trial name
- NCT03406624
- Testing
- Biopsy
- Where
- 4 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Chronic Low Back Pain
Clinical Outcome After Lumbar Fusion
The main objective of this prospective study is to compare the clinical outcomes after lumbar fusion for chronic low back pain using the four techniques commonly employed in our surgical practice.
- Trial name
- NCT03155789
- Testing
- Lumbar Fusion
- Volunteers
- 90 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Low Back Pain, Spondylolisthesis
Effects of Exercise Intervention in Patients With Spondylolisthesis Related LBP
The first purpose of this study is to define parameters of the trunk neuromuscular functions that are pathologically altered in patients with low back pain due to spondylolytic spondylolisthesis.
- Trial name
- EXER-SPO-TNC (NCT01985776)
- Testing
- Exercise intervention, Exercise and e-stim
- Where
- 4 sites in Slovenia
- Volunteers
- 48 people
- Sponsor
- University of Primorska
Central Sensitisation, Fibromyalgia
The Nociceptive Flexion Reflex as a Diagnostic Tool of Central Sensitization
This experimental study will investigate whether the decreased NFR threshold and increased NFR temporal summation, which are frequently observed in chronic pain patients, are only symptomatic manifestations that occur in the…
- Conditions
- Central Sensitisation, Fibromyalgia, Neck Pain, Low Back Pain
- Trial name
- NFR-CS (NCT05321550)
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Ghent
Low Back Pain
Effects of Kinesio Tape on Chronic Low Back Pain
This clinical trial aims to examine kinesiotape's (KT) short-term effect on individuals with nonspecific chronic LBP (CLBP), including back-specific body perception, pain, functional disability, and physical activity.
- Trial name
- NCT05866159
- Testing
- Kinesiotape using Rocktape®
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Low Back Pain
Nucleotides and B Vitamins in the Treatment of Low Back Pain
This is a double-blind, randomized study in parallel groups of subjects presenting with low back pain. Randomized subjects will receive treatment for 60 days with either a combination of nucleotides and vitamin B12 or vitamin…
- Trial name
- NCT02640417
- Testing
- Nucleotides + B12, B Vitamins
- Volunteers
- 300 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Chronic Low Back Pain
Investigation of Immediate, Short and Long Term Effects of Mulligan Mobilization With Movement Techniques in Nonspesific Chronic Low Back Pain
Introduction: Although the effectiveness of many mobilization methods in chronic low back pain (CLBP) was shown, these effects were not monitored in the long term.
- Trial name
- NCT04802850
- Testing
- Mulligan mobilization with movement
- Volunteers
- 36 people
- Sponsor
- Suleyman Demirel University
Chronic Low-back Pain
Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment
This study will identify unique signatures that people have which can cause pain by evaluating biological, psychological, and social markers using artificial intelligence.
- Trial name
- IMPACT (NCT06106191)
- Testing
- Mindfulness meditation, Perspectives on pain, Discussion
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Boston Medical Center
Lumbar Spine Degenerative Changes, Lumbar Spine Surgery
Rehabilitation With Empowered STrategies to Optimize REcovery
The main goal of this clinical trial is to understand the benefits of remotely delivered Empowered Relief in patients undergoing lumbar spine surgery.
- Trial name
- RESTORE (NCT07406997)
- Testing
- Empowered Relief, Education
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Sedentary Behavior, Motor Control Impairment
Lumbar Stabilization Exercises in Sedentary Adults
This pilot randomized controlled trial will examine the effects of a four-week lumbar spine stabilization exercise program on motor control, dynamic balance, and quality of life in healthy sedentary adults.
- Conditions
- Sedentary Behavior, Motor Control Impairment, Quality of Life
- Trial name
- NCT07447167
- Testing
- Ergonomic and Stretching Instructions, Lumbar Stabilization Exercise Program
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Chronic Low Back Pain
Aging Back Clinics
The purpose of this study is to compare two different ways to treat chronic low back pain. The two types of treatment that the investigators will compare are called Usual Care and ABC Care. Usual Care tends to focus on the spine.
- Trial name
- NCT03564600
- Testing
- Aging Back Clinics management
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Radiculopathy, Low Back Pain
Low Back Study to Compare Traditional Physical Therapy With Combined Therapy Protocol
The most common chronic low back pain conditions are a consequence of disc disease as well as muscular and bony etiologies. The discs degenerate and weaken, bulge and are pushed into the space containing the spinal cord or a…
- Trial name
- NCT01236092
- Testing
- conservative therapy - traction, vibration, exercise
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Michael Wilson & Associates Health Care Consulting, LLC
Low Back Pain
Investigation of the Effects of Classical Massage Application on Individuals With Chronic Low Back Pain
The aim of this study is to examine the effects of classical massage on pain, spinal mobility, functional and psychological state, and life quality in individuals with chronic low back pain.
- Trial name
- NCT05769192
- Testing
- Classical physiotherapy and classical massage
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Opioid Use, Low Back Pain
Impact of DuoTherm on Opioid Use and Low Back Pain
Evaluate the difference in opioid use, pain intensity and pain interference in patients with moderate to severe low back pain using DuoTherm multimodal harmonic mechanical stimulation (M-Stim) unit compared to Transcutaneous…
- Trial name
- NCT04491175
- Testing
- M-Stim, TENS
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Back Pain Lower Back Chronic
Virtual Reality for the Treatment of Chronic Low Back Pain
Chronic low back pain is highly prevalent in US adults and is a major cause of missed work days and disability. While several treatment options exist, chronic opioids are commonly used for these conditions even though there are…
- Trial name
- VR (NCT04273919)
- Testing
- HTC Vive with Karuna Virtual Reality Program, HTC Vive with Lumen Program
- Where
- United States
- Sponsor
- University of Pennsylvania
Disk Herniated Lumbar, Radicular Pain
Percutaneous Intradiscal Radiofrequency as A Treatment for Radicular Pain From Lumbar Disc Herniation
The goal of this clinical trial is to demonstrate the efficacy of percutaneous intradiscal radiofrequency as a treatment for radicular pain from lumbar disc herniation.
- Conditions
- Disk Herniated Lumbar, Radicular Pain, Intradiscal Radiofrequency
- Trial name
- NCT05747807
- Testing
- Percutaneous intradiscal radiofrequency treatment
- Where
- Thailand
- Volunteers
- 18 people
- Sponsor
- Chulalongkorn University