Clinical trials: Lumbar Pain
Degenerative Disc Disease
Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV)
This trial pretends to validate for clinical use a bioengineered product composed of mesenchymal stem cells produced by the Instituto de Biologia y Genetica Molecular (IBGM), Valladolid (MSV, which have already been approved by…
- Trial name
- MSV-DISC (NCT02440074)
- Testing
- Autologous bone marrow mesenchymal stem cells
- Sponsor
- Red de Terapia Celular
Acute Low Back Pain
Psychosocial Treatment for Acute Low Back Pain
Acute low back pain (severe pain that comes on suddenly and lasts a relatively short time) is very common in the United States, and accounts for substantial illness, functional limitations, pain, and health care costs.
- Trial name
- NCT00000418
- Testing
- Psychosocial intervention
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Indiana University
Low Back Pain, Recurrent, Low Back Pain
Back2LiveWell: Community Based Prevention of Back Pain Flare-ups
The primary objective of this study is to compare the effectiveness and cost-effectiveness of an individualized group based exercise and education program supported in the community to a control group of usual care in preventing…
- Trial name
- Back2LiveWel (NCT03328689)
- Testing
- Physical activity program, Control group standard care
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- McMaster University
Chronic Low Back Pain, Type 2 Diabetes Mellitus
OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus
The study hypothesis is based on osteopathic medical philosophy that: 1) the body is a unit; 2) the body has inherent self-regulatory mechanisms; 3) structure and function are interrelated; and 4) rational treatment is based on…
- Trial name
- NCT02054650
- Testing
- Osteopathic Manual Treatment (OMT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Texas Health Science Center
Herniated Lumbar Disk
Confirmatory Clinical Study of Oxiplex
This is a prospective, multi-center, randomized, controlled, patient and evaluator-blinded clinical study to assess the safety and effectiveness for the reduction of pain and symptoms following lumbar surgery.
- Trial name
- NCT03433391
- Testing
- Oxiplex, Surgery Only
- Where
- 17 sites in United States
- Volunteers
- 135 people
- Sponsor
- FzioMed
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative, Anesthesia, Regional
Comparison of the Efficiency of PENG Block and ESP Block Used for Postoperative Analgesia in Elective Hip Surgery
The aim of the study is to determine whether the traditional intravenous analgesia technique or the ultrasound-guided pericapsular nerve group block or the unilateral erector spina plane block technique is superior in…
- Conditions
- Pain, Postoperative, Anesthesia, Regional, Hip Surgery, Ultrasound-Guided
- Trial name
- NCT05802589
- Testing
- Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block, no peripheral block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Osteoarthritis of the Lumbar Spine, Pain, Back
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis of the Lumbar Spine
This is a Phase 3, Multicenter, Randomized, 22 Week, Double-Blind, Placebo Controlled and 3-Week, Open-Label Study to Evaluate the Efficacy and Safety of X0002 Spray in relief of the signs and symptoms of Subjects with…
- Trial name
- NCT03110523
- Testing
- X0002
- Sponsor
- Techfields Pharma Co. Ltd
Cancers, Pain, Lower Back Pain
Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy
The purpose of this study is to evaluate the long-term safety and tolerability of oxymorphone ER as an analgesic in cancer and lower back pain subjects having chronic moderate to severe pain.
- Trial name
- NCT00904280
- Testing
- Oxymorphone ER
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Low Back Pain, Non Specific Chronic Low Back Pain
Effects of Multifidus Lift Exercise on Endurance, Pain, and Disability in University Students With Low Back Pain
Nonspecific low back pain is a common musculoskeletal problem that also affects many young adults, including university students. It can negatively impact academic performance, daily life, and overall well-being.
- Conditions
- Low Back Pain, Non Specific Chronic Low Back Pain, Healthy Vollunteer
- Trial name
- LBP-MULEX (NCT07182825)
- Testing
- Modified Multifidus Lift Exercise (MLE)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Guler
Low Back Pain
Ultrasound-CT Fusion Image-guided Minimally Invasive Interventional Treatment of Lumbosacral Nerve Roots
The study is aimed at patients with low back and leg pain. The patients in the experimental group were guided by ultrasound-CT fusion imaging to insert the lumbar nerve root puncture needle.
- Trial name
- NCT04953520
- Testing
- ultrasound-CT fusion imaging, pure ultrasound guidance
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Non-specific Low Back Pain (NSLBP)
Erector Spinae Plane Block for Acute Low Back Pain
Non-Specific low back pain (NSLB) is an important public health problem with a major economic and social impact. It is defined by the location of pain, between the lower rib margins and the lumbar vertebrae.
- Trial name
- ESP-BACK (NCT07434024)
- Testing
- Erector Spinae Plane Block with isotonic saline, Erector Spinae Plane Block with local anesthetic
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Low Back Pain, Recurrent
Treatment and Companion Diagnostics of Lower Back Pain Using SCENAR and Passive Medical Radiometry (MWR)
Evaluation of the effectiveness of treatment of nonspecific pain in the lower back (LBP) is currently largely based on the patient's subjective feelings.
- Trial name
- SCENAR/MWR (NCT05223946)
- Testing
- Microwave Radiometry, SCENAR-CHENS-01, Traditional Combination Therapy
- Where
- 2 sites in Kyrgyzstan
- Volunteers
- 55 people
- Sponsor
- Kyrgyz State Medical Academy
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Lower Back Pain
Restorative Exercise for Strength Training and Operational Resilience (RESTORE) for Chronic or Recurrent Low Back Pain
The purpose of the study is to learn about the effect of integrative therapies on chronic or recurrent low back pain. The intervention called RESTORE (Restorative Exercises for Strength Training and Operational Resilience) is…
- Trial name
- RESTORE (NCT02132910)
- Testing
- RESTORE Intervention
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Low Back Pain, Core Stability
Lumbar School Training or Core Stabilization Exercises on Pain, Mobilization and Quality of Life Low Back Pain
Chronic low back pain (CLBP) is defined as low back pain lasting longer than three months. CLBP is one of the most common and expensive diseases in terms of both labour loss and treatment costs, and it is very important to treat…
- Conditions
- Low Back Pain, Core Stability, Core-based Exercise, Back School
- Trial name
- Lowbackpain (NCT06203340)
- Testing
- Core stabilizasyon and lumbal back school
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Pain, Postoperative
TAP Block Efficacy After Lumbar Spine Surgery Through Anterior Approach: a Randomized, Placebo-controlled Study
Anterior Lumbar Interbody Fusion (ALIF) as well as Direct Lateral Interbody Fusion (DLIF) are established techniques for lumbar interbody fusion.
- Trial name
- TAP-LIF (NCT02778178)
- Testing
- ropivacaine plus clonidine, ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Acute Pain
OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department
Patients 18 to 65 years old who present within 72 hours of onset pain will be considered for study enrollment. Patients with the acute musculoskeletal low back or neck pain based on ED history and structural physical exam will be…
- Trial name
- NCT06987578
- Testing
- OMT vs. Ibruprofen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- St. Joseph's Regional Medical Center, New Jersey
Athletic Injury, Low Back Pain
Postural Control and Trunk Neuromuscular Activation in Athletes With Chronic Low Back Pain
The relevance of this study is given by the feasibility to assess the effect of an intervention program based on the postural control and trunk neuromuscular activity, comparing two methods: stabilization exercises vs.
- Trial name
- PCMALBP (NCT02969785)
- Testing
- G1: exercises for lumbar stabilization, G2: back strengthening exercises
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Low Back Pain
Transpubic Symphysis Reset for Treatment of Low Back Pain
To verify the efficacy of transpubic symphysis reset therapy for low back pain, and provide support for the clinical application of this treatment.
- Trial name
- NCT02906540
- Testing
- Transpubic symphysis reset therapy group, Physiotherapy group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
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