Clinical trials: Lumbar Puncture
Leukemia-Lymphoma
Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures
A common procedure in children with cancer is the spinal tap, or lumbar puncture (LP), in which a needle is inserted into the spinal canal.
- Trial name
- NCT04003012
- Testing
- EMLA, Lidocaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CAMC Health System
Febrile Convulsions
The Relevance of Performing Lumbar Puncture in Infants Aged 3 to 12 Months With First Episode of Febrile Convulsion
The actual recommendations for infants aged 3 to 12 months presented with first episode of Febrile Convulsions highly recommend performing lumbar puncture in order to rule out Bacterial Meningitis.
- Trial name
- NCT01443611
- Where
- Israel
- Volunteers
- 122 people
- Sponsor
- HaEmek Medical Center, Israel
HIV Positive
Thinking and Memory Problems in People With HIV
Background: People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration.
- Trial name
- NCT01875588
- Where
- United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lumbar Puncture
Ultrasound-assisted vs Palpation-guided Lumbar Punctures
The goal of this randomized clinical trial is to determine whether ultrasound-assisted lumbar puncture improves first-needle insertion success compared with the standard palpation technique in adults undergoing a clinically…
- Trial name
- NCT07824284
- Testing
- Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- The Cooper Health System
Meningitis in Children
The Use of an Audio-visual Method in Counseling for Pediatric Lumbar Puncture Procedure
The goal of this clinical trial is to compare the use of usual verbal counseling supported by a video illustration comparing to the use of usual verbal counseling alone prior to obtaining spinal fluid ( Lumbar puncture - LP )…
- Trial name
- NCT07409220
- Testing
- Audio-visual tool/ Video
- Where
- Oman
- Volunteers
- 154 people
- Sponsor
- Oman Ministry of Health
Pain
Contribution of Hypnosis During a Lumbar Puncture.
The purpose of this study is to assess the effect of hypnosis, as add on therapy, on patients requiring a lumbar puncture (LP) as part of their medical management.
- Trial name
- HYPNOPLUS (NCT05092906)
- Testing
- LP with complementary hypnoanalgesia, LP with standard of care
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Lumbar Puncture
Ultrasound Assisted Lumbar Puncture in the Neonate
Clinicians are often unable to successfully do a spinal tap. Ultrasound has been proposed as a method to improve success but it is not known if it helps. This study is designed to see if ultrasound improves the success rate.
- Trial name
- NCT02918149
- Testing
- Palpation Landmark Technique, Ultrasound-Assisted Technique LP
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Children's Hospital of Philadelphia
Chronic Low Back Pain (CLBP)
Disc Puncture Does Not Accelerate Degenerative Changes in Lumbar Discs of Patients With Discogenic Pain
Procedures 10 years ago performed included intradiscal nucleoplasty (ACUTHERM) and intradiscal electrothermal therapy (IDET). At follow up MRI scans evaluated by two blinded specialists for disc degeneration were carried out.
- Trial name
- NCT07567404
- Testing
- Intradiscal electrothermal Therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb
Neonate, Meningitis
Repeat Lumbar Puncture at 24 Versus 48 Hours After Traumatic Lumbar Puncture in Neonates
Visibly traumatic as well as microtraumatic lumbar punctures (LP) are very common in the neonatal period. The presence of blood makes it difficult to interpret cerebro-spinal fluid (CSF) findings.
- Conditions
- Neonate, Meningitis, Spinal Puncture
- Trial name
- NCT04794881
- Testing
- 24 hours, 48 hours
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Spinal Puncture
Identification of Spine Structures by Using BIP-Needles
The main purpose of the study is to assess the feasibility and clinical performance of impedance based tissue identification in various spine structures.
- Trial name
- NCT02602912
- Testing
- Injeq Bioimpedance Probe (BIP) Needle
- Where
- Finland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Injeq Ltd
Anesthesia, Local, Nerve Pain
SEQ Block for Perioperative Analgesia in Acetabular Surgery
The study will evaluate ultrasound guided SEQ block: single puncture combined lumbar erector spinae plane block and paraspinous sagittal shift (PSSS) quadratus lumborum block when compared with conventional intravenous morphine…
- Conditions
- Anesthesia, Local, Nerve Pain, Pain, Postoperative, Acetabular Fracture
- Trial name
- NCT04688814
- Testing
- Single puncture combined lumbar erector spinae plane block and quadrates lumborum block, Morphine Sulfate
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Alexandria University
HIV - Human Immunodeficiency Virus, Cognitive Symptoms
COMO: Cognition Study With HIV+ Patients (CTNPT 015)
The purpose of this study is to contribute evidence towards the potential to improve cognition in HIV+ individuals experiencing cognitive decline through personalized change in antiretroviral (ARV) medication.
- Trial name
- COMO (NCT02144688)
- Testing
- Change in antiretrovirals
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Marie-Josée Brouillette
Pediatric Lumbar Puncture
Identification of Cerebrospinal Fluid With Injeq IQ-Needle During Paediatric Lumbar Puncture
This is clinical feasibility study on the device performance with paediatric patients. The main objective is to validate the performance of investigational device in distinguishing and identifying the cerebrospinal fluid (CSF)…
- Trial name
- NCT02792660
- Testing
- Injeq IQ-Needle
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Injeq Ltd
Meningitis, Pediatric Disorder
Bedside Ultrasound on the Effectiveness of Lumbar Puncture in Children.
The aim of the study is to assess the influence of ultrasound examination of the lumbar spinal canal on the effectiveness of lumbar puncture. An open-label, randomized interventional study.
- Trial name
- NCT06584864
- Testing
- bedside ultrasound examination of the lumbar spinal canal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
a Randomized Controlled Trial
Randomized Control Trial Comparing CMPAT and MAT for Lumbar Puncture
The lumbar puncture (LP) technique is a widely utilized method for diagnosis and treatment purposes. Recently, the paramedian approach technique (PAT) has garnered increasing interest due to its advantages over the midline…
- Trial name
- NCT05795075
- Testing
- Computerized Modified Paramedian Approach Technique, Conventional Midline Approach Technique
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Fujian Medical University Union Hospital
Late Infantile Neuronal Ceroid Lipofuscinosis, Batten Disease
Collection of Cerebrospinal Fluid in Healthy Children
The purpose of this study is to obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late…
- Trial name
- NCT01698229
- Testing
- Group 1
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Intracranial Pressure
Intracranial Pressure vs Percentage Body Fat
Background: It has already been established that there is a weak positive relationship between increased intracranial pressure (ICP), as measured by lumbar puncture manometry, and increased Body Mass Index (BMI).
- Trial name
- NCT03144297
- Testing
- Lumbar puncture, BOD POD (air-displacement plethysmography)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Spinal Puncture
A Prospective Observational Study Comparing Computer-Assisted Paramedian Approach Versus Conventional Midline Approach for Lumbar Puncture
The goal of this clinical trial is to compare the effects of CMPAT and MAT in patients undergoing LP. Participants will be randomly assigned to either the CMPAT treatment group (group A) or the MAT treatment group (group B).
- Trial name
- NCT06418841
- Testing
- Computer-Assisted Paramedian Approach Technique, Conventional Midline Approach Technique
- Volunteers
- 84 people
- Sponsor
- Fujian Medical University Union Hospital
Spinal Puncture Complications, Simulation-based Training
The Effect of Simulation-Based Training on Performance and Stress in the Clinical Setting
This study will investigate the effect of simulation-based training with mastery learning (SBML) on novice performers' lumbar puncture (LP) performance in a clinical setting.
- Conditions
- Spinal Puncture Complications, Simulation-based Training, Stress, Emotional
- Trial name
- NCT03163927
- Testing
- Simulation-based training
- Where
- 3 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-Lumbar Puncture Headache
A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients
The purpose of this study is to o determine whether the modified LP procedure reduces the incidence of PLPH to 5% or lower, to determine whether the modified LP procedure reduces the frequency of epidural blood patch (EBP) usage…
- Trial name
- NCT06062446
- Testing
- Modified Lumbar Puncture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston