Clinical trials: Lumbar Radicular Pain
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
Lumbar Disk Herniation
Effectiveness of Lumbar Traction in Lumbar Disk Herniation
The purpose of this study is to compare the clinical outcome of medical treatment associated with lumbar traction and medical treatment alone in the treatment of lumbar disk herniation.
- Trial name
- NCT02793440
- Testing
- cortivazol treatment, lumbar traction
- Where
- France
- Volunteers
- 412 people
- Sponsor
- CHU de Reims
Lumbar Radiculopathy
Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain
To evaluate the efficacy of usage of High-voltage pulsed radiofrequency on DRG in comparison to standard-voltage pulsed radiofrequency intervention in patients with chronic lumbosacral radicular pain
- Trial name
- NCT05713032
- Testing
- Pulsed radiofrequency on lumbar dorsal root ganglion
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Alexandria University
Radiculopathy Lumbar
Spinal Decompression Therapy in Radicular Chronic Low Back Pain
The study design was randomized control trial and sampling technique was lottery method. After inclusion and exclusion criteria, sample populations were divided into experimental (group A) and control group (group B).
- Trial name
- NCT04701879
- Testing
- Spine decompression with core stability exercises, Spine decompression
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Radiculopathy Lumbar
Glucocorticoid Injection in Patients With Lumbar Radicular Pain
The purpose of this study is to demonstrate the efficacy of intramuscular betamethasone injection on pain and other clinical parameters in patients with radicular pain due to lumbar disc herniation.
- Trial name
- NCT05571046
- Testing
- Glucocorticoids
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Lumbosacral Radicular Pain
Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
This is a research study of SP-102, an experimental medication designed to relieve pain in patients with a specific type of leg pain.
- Trial name
- NCT03372161
- Testing
- SP-102
- Where
- 37 sites in United States
- Volunteers
- 401 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region
Radiofrequency for Chronic Radicular Lumbar Pain: Geriatric vs. Young Patients
This study aims to evaluate the treatment response and lumbar magnetic resonance imaging (MRI) findings of patients who have undergone pulsed radiofrequency therapy for chronic radicular lumbar pain at the dorsal root ganglia.
- Conditions
- Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region, Chronic Pain
- Trial name
- NCT06903949
- Testing
- Lumbar Dorsal Root Ganglia Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Radicular Pain
Interest of Virtual Reality Headset During Injection in Patients With Back Pain and Sciatica
For a few years, publications have been published concerning the use of virtual reality headsets in the field of medicine and particularly in various specialities.
- Trial name
- Epi-RéV (NCT05505968)
- Testing
- Virtual Reality Headset
- Where
- France
- Volunteers
- 116 people
- Sponsor
- CHU de Reims
Radiculopathy Lumbar, Radiculopathy Sacral
The Selective Intraperineural Nerve Root Block Study
Before lumbosacral decompression surgery for radicular pain, selective nerve root block(SNRB) is a common procedure to identify the responsible compressed nerve root(RCNR) and predict surgical outcomes.
- Conditions
- Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites, Herniated Disc
- Trial name
- SINRBS (NCT07531485)
- Testing
- Selective Intraperineural Nerve Root Block(SINRB), single-level lumbar decompression surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'an Honghui Hospital
Herniated Disc
Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain
The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications.
- Trial name
- NCT07036445
- Testing
- Epidural Steroid Injection, Epidural platelet-rich plasma injection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Lumbar Disc Herniation
Barricaid EU Post Market Study for Primary Lumbar Disc Herniation
The purpose of this multi-center post marketing surveillance study is to monitor the safety and performance of the Barricaid® ARD when used to surgically reconstruct the anulus of the L1 - S1 spinal disc.
- Trial name
- NCT01534065
- Testing
- Barricaid
- Volunteers
- 45 people
- Sponsor
- Intrinsic Therapeutics
Low Back Pain (LBP), Lumbar Radiculopathy
The Effect of Needle Insertion Angle on Contrast Distribution and Treatment Outcomes in S1 Transforaminal Epidural Steroid Injections
Nerve compression due to lumbar disc herniation (lumbosacral radiculopathy) is a condition characterized by pain in the lower back and legs and restricted lumbar joint movement due to the compression of nerves emerging from the…
- Conditions
- Low Back Pain (LBP), Lumbar Radiculopathy, Intravascular Injection
- Trial name
- Transforaminal (NCT06801990)
- Testing
- S1 transforaminal epidural steroid(dexamethasone) injection
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Marmara University
Radiculopathy Lumbar, Low Back Pain
Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification
Low back pain is a common disease in all ages and it effects seriously quality of life. Medical treatment,interventional methods and surgery are the treatment options.
- Conditions
- Radiculopathy Lumbar, Low Back Pain, Disc Herniation, Injections, Epidural
- Trial name
- NCT06275529
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Lumbosacral Radicular Pain
Corticosteroid Lumbar Epidural Analgesia for Radicular Pain 2
This is a research study of SP-102, an experimental medication designed to relieve pain in patients with moderate to severe sciatica (pain in the lower back, hips, buttocks and legs).
- Trial name
- CLEAR 2 (NCT07579351)
- Testing
- SP-102, Dexamethasone Sodium Phosphate 10 MG/ML
- Volunteers
- 755 people
- Sponsor
- Semnur Pharmaceuticals, Inc.
Low Back Pain
Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population
Subjects (N=120) who have had non-radicular low back pain, believed by clinical assessment and imaging to be consistent with lumbar zygapophysial joint (Z-joint) generated pain, who have failed conservative therapy including…
- Trial name
- NCT01382771
- Testing
- Intra-articular corticosteroid injection, Intra-articular saline injection
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Florida
Lumbar Disc Herniation
Effect of Pulsed Mode Radiofrequency as a Treatment of Lumbar Disc Related Radicular Pain on Tumor Necrotic Factor α Level
Lumbar radiculopathy is a term that describes symptoms of pain, numbness, and/or weakness that radiate along the sciatic nerve from the lower back to the buttocks and leg (1).
- Trial name
- NCT05288920
- Testing
- Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection, Transforaminal injection of Steroids alone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Radiculopathy Lumbar
A Two-part Proof-of-Concept Study Assessing the Safety and Efficacy of LAT8881 in Lumbar Radicular Pain
The study consists of two parts. Part A will evaluate the safety and tolerability of intravenous LAT8881 in healthy volunteers using an ascending dose schedule.
- Trial name
- NCT05298306
- Testing
- LAT8881
- Where
- Australia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lateral Pharma Pty Ltd
Acute Sciatica
A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain
Aim: In subjects with acute sciatica (≤ 4 weeks duration), this is a pilot comparative effectiveness study to evaluate feasibility and to determine final sample size for a future adequately powered randomised controlled trial of…
- Trial name
- SCIATICA (NCT03240783)
- Testing
- Betamethasone OR Dexamethasone Injectable, Normal Saline Flush, 0.9% Injectable Solution, Dexamethasone Oral Tablet
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- St George Hospital, Australia